Genomics

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Researchers use guide RNAs to improve base editing system

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

1 Aug 2018

Father’s genes can affect quality of maternal care received by a newborn

A father’s genes are no longer thought to just provide a blueprint for the growth and development of their offspring.

1 Aug 2018

New DNA test predicts how humans may respond to cannabis

Today marks the launch of the Endocanna Health "Cannabinoid DNA Variant Test" the most comprehensive personalized cannabis DNA test available on the market today.

1 Aug 2018

Mutation 'hotspots' in DNA could help determine cancer risk

Researchers have identified DNA 'hotspots' where gene mutations are significantly more likely to arise. The findings will be used to determine cancer risk.

31 Jul 2018

Researchers sequence complete mitochondrial genome of malaria mosquitoes

A team led by scientists from the Johns Hopkins Bloomberg School of Public Health has sequenced and annotated the first complete mitochondrial genome of Anopheles funestus, one of the main vectors of malaria in sub-Saharan Africa.

31 Jul 2018

Gene linked to hair loss could be exploited to improve cancer immunotherapy

A gene that's associated with an autoimmune form of hair loss could be exploited to improve cancer immunotherapy, suggests a new mouse study by Columbia University Irving Medical Center (CUIMC) researchers.

31 Jul 2018

New study explores human T cell function under inflammatory conditions

The Marshall University School of Pharmacy, in collaboration with the Marshall University Joan C. Edwards School of MedicineGenomics Core, recently released a new study that explores human T cell function under inflammatory conditions.

31 Jul 2018

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Despite high hopes and high investment in CRISPR-Cas9 gene editing, scientists still have a lot to learn about how it works in humans.

31 Jul 2018

Bt modification in maize does not affect beneficial microorganisms

Bt modification in maize does not affect non-target beneficial microorganisms such as endophytes. Although Bt maize is one of the most popular GM crops in the world, little is known about potential impacts on ecosystem functionalities.

30 Jul 2018

Researchers discover how breast cells prevent cancer invasion

Researchers have shown that the cell layer surrounding breast milk ducts reaches out and engulfs cancerous cells to stop their spread.

30 Jul 2018

Computational platform predicts how to convert one cell type into another

Researchers have developed a computational platform that predicts how one subtype of cells can be converted into another subtype.

30 Jul 2018

Major genome science study offers insights into cardiac electrical diseases

New knowledge about biological processes related to the heart's electrical activity has been gained through a major genome science study. The research had the largest sample size ever of a project of this type.

28 Jul 2018

New approach shows important role of microRNAs in papillomavirus life cycle

The discovery of microRNAs encoded by papillomaviruses supports the important role of these small molecules in persistent infection, according to a study published July 26 in the open-access journal PLOS Pathogens.

27 Jul 2018

Researchers identify genes linked to childhood nephrotic syndrome

Childhood nephrotic syndrome is the most frequently occurring chronic kidney disease among children. A Japanese research team has identified a group of genes that are strongly related to the development of childhood nephrotic syndrome.

27 Jul 2018

Answer to decades-old mystery may allow some children to avoid bone marrow transplantation

Researchers have helped solve a decades-old mystery about which mutations are responsible for an inherited bone marrow disorder.

27 Jul 2018

Study shares public views of using gene editing to change unborn baby’s genetic makeup

A majority of Americans support the idea of using gene editing with the goal of delivering direct health benefits for babies.

27 Jul 2018

Mutations of IRF2BPL gene associated with previously undiagnosed neurological disorder

An international team of scientists, including researchers from Baylor College of Medicine, has discovered mutations of gene IRF2BPL that are associated with a previously undiagnosed neurological disorder in seven unrelated individuals.

27 Jul 2018

Scientists discover gene that predicts arthritis severity

Scientists have discovered a new gene that is associated with disease severity in rheumatoid arthritis. HIP1 produces an inflammatory molecule which drives RA.

26 Jul 2018

Anti-cancer gene may switch side and promote cancer growth, shows study

It doesn't often happen that army generals switch sides in the middle of a war, but when cancer's attack is underway, it may even cause a gene that acts as the body's master defender to change allegiance.

26 Jul 2018

Researchers identify gene from Ebola virus in Myotis bats

A gene from the deadly Ebola virus that allows the virus to escape from the human immune system has been identified in the genome of a group of bats that is found worldwide, including North America.

25 Jul 2018