Genomics

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Findings confirm analytical principle that describes mutational processes and cancer development

When a cell develops into a tumor, something has gone terribly wrong: the uncontrolled growth, invasion of nearby tissues and finally metastasis are the result of many consecutive DNA mutations.

9 May 2018

Researchers harness the precision of CRISPR to knock out single genes in yeast

Researchers have used CRISPR-Cas9 to develop a technology that can precisely target any gene in the yeast species Saccharomyces cerevisiae.

8 May 2018

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Not all of your genome needs to be active at any given time. Some regions are prone to hopping around the genome in problematic ways if left unchecked; others code for genes that need to be turned off in certain cells or at certain times.

8 May 2018

Genes that control the immune system may play role in hair graying

A study has found a link between genes that warn our bodies of a pathogenic infection and genes that play a role in determining hair color.

4 May 2018

Researchers discover glutamine-dependent activation of cell growth and autophagy

The human body consists of about 35 trillion cells, so it could be said that overall body growth is the growth of individual cells.

3 May 2018

New GP-write project to develop ultra-safe cells resistant to natural viruses

The Center for Excellence in Engineering Biology and the leadership of Genome Project-write today announced its first grand-scale community-wide project, to develop "ultra-safe cells" that resist natural viruses and potentially radiation, freezing, aging and cancer.

2 May 2018

NASA finds new solutions for rapid in-flight molecular testing aboard the space station

What do astronauts, microbes, and plants all have in common? Each relies on deoxyribonucleic acid (DNA) - essentially a computer code for living things - to grow and thrive.

2 May 2018

Scientists discover new target in the treatment of pulmonary hypertension

In a recent study, scientists found that eliminating the FoxM1 gene could improve outcomes for patients with pulmonary hypertension.

1 May 2018

New studies show potential for using genetic information to create personalized vision care

Two new studies demonstrate potential future opportunities to use genetic information to treat vision conditions. The new studies are being presented at the 2018 Annual Meeting of the Association for Research in Vision and Ophthalmology in Honolulu, Hawaii, Sunday, April 29 – Thursday, May 3.

30 Apr 2018

Gene therapy is the best stratagem to impact the course of GM2 gangliosidosis

Since its clinical description in 1881, Tay-Sachs disease has had almost totemic significance as a cruel and relentless genetic condition that destroys the developing brain of babies and young children.

28 Apr 2018

BIO announces programming information for gene editing and synthetic biology at 2018 World Congress

The Biotechnology Innovation Organization (BIO) today announced programming information for gene editing and synthetic biology at the 2018 World Congress on Industrial Biotechnology.

28 Apr 2018

Telomerase discovery paves way for drugs to combat aging and cancer

Researchers have published the first detailed image of the molecular structure of human telomerase, the enzyme that lengthens chromosomes and extends the lifespan of a cell.

27 Apr 2018

Cell lineage is not pre-determined, finds new study

Scientists have mapped the developmental trajectories of more than 40,000 individual cells and found that cell fates are determined much later than previously thought.

27 Apr 2018

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression lasting for six months after a single treatment.

27 Apr 2018

New study identifies 44 genomic variants linked to depression

A new meta-analysis of more than 135,000 people with major depression and more than 344,000 controls has identified 44 genomic variants, or loci, that have a statistically significant association with depression.

26 Apr 2018

Advances in genetic testing give new insights to parents of children with epileptic encephalopathy

Advances in genetic testing offer new insights to parents who have a child with a rare but serious form of epilepsy, epileptic encephalopathy (EE), found in one of about every 2,000 births and characterized by developmental disabilities as well as horrible seizures.

26 Apr 2018

Researchers uncover how obesity leads to cancer in epithelial cells

A new study led by researchers at Hokkaido University has shown that obesity may enhance the progression of cancer, while aspirin may protect against it.

26 Apr 2018

Doctors cure sickle cell patients using allogeneic stem cells

Seven adults with sickle cell disease have been cured by doctors at the University of Illinois Hospital, thanks to the development of a new protocol for stem cell transplantation.

25 Apr 2018

Researchers discover significant distortions in leading genetics study method

Many conclusions drawn from a common approach to the study of human genetics could be distorted because of a previously overlooked phenomenon, according to researchers at the Department of Genetics and Genomics Sciences at the Icahn School of Medicine at Mount Sinai and collaborators from Massachusetts General Hospital and the Broad Institute.

25 Apr 2018

Salk researchers develop new glioblastoma model using gene-edited organoids

Glioblastoma multiforme (GBM) is an incredibly deadly brain cancer and presents a serious black box challenge. It's virtually impossible to observe how these tumors operate in their natural environment and animal models don't always provide good answers.

25 Apr 2018

Genomics

Findings confirm analytical principle that describes mutational processes and cancer development

Researchers harness the precision of CRISPR to knock out single genes in yeast

Scientists discover a small family of proteins that control inclusion of DNA methylation marks in genome

Genes that control the immune system may play role in hair graying

Researchers discover glutamine-dependent activation of cell growth and autophagy

New GP-write project to develop ultra-safe cells resistant to natural viruses

NASA finds new solutions for rapid in-flight molecular testing aboard the space station

Scientists discover new target in the treatment of pulmonary hypertension

New studies show potential for using genetic information to create personalized vision care

Gene therapy is the best stratagem to impact the course of GM2 gangliosidosis

BIO announces programming information for gene editing and synthetic biology at 2018 World Congress

Telomerase discovery paves way for drugs to combat aging and cancer

Cell lineage is not pre-determined, finds new study

Researchers use CRISPR/Cas9 technique to turn off gene that regulates cholesterol levels in adult mice

New study identifies 44 genomic variants linked to depression

Advances in genetic testing give new insights to parents of children with epileptic encephalopathy

Researchers uncover how obesity leads to cancer in epithelial cells

Doctors cure sickle cell patients using allogeneic stem cells

Researchers discover significant distortions in leading genetics study method

Salk researchers develop new glioblastoma model using gene-edited organoids

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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