Genomics

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Study reveals mechanism behind eye loss in blind cavefish

Blind cavefish lose critical eye tissues within a few days after their eyes begin to develop.

7 Jun 2018

Study finds how colon cancer alters its genes to escape the immune system

A UCLA-led study has found how colon cancer alters its genes during development in order to avoid detection by the immune system, creating a specific genetic imprint in the process.

6 Jun 2018

Researchers develop novel tool to analyze millions of single cells simultaneously

New research led by Holger Heyn at the Centro Nacional de Análisis Genómico of the Centre for Genomic Regulation, presents a sophisticated computational framework to analyze single-cell gene expression levels, scalable to process millions of individual cells.

From 10x Genomics, Inc. 6 Jun 2018

Finnish research solves family blood mystery

It's the late 1970s, and a man with an unexplained high hemoglobin level (Hb) is referred to Namsos Hospital north of Trondheim, Norway. It turns out that four members of his family have the same condition. Doctor Kjell Kanelønning is the physician who treats the family.

6 Jun 2018

Genopole opens application process for Shaker and Booster programs to international candidates

Genopole, a French biocluster dedicated to research in the fields of genetics and biotechnology, today announces that it is now accepting applications for the third intake of its support programs titled Shaker, designed for people running innovative projects, and Booster, aimed at companies that are less than two years old.

5 Jun 2018

Study identifies four tumor survival strategies in childhood cancer

Researchers have identified four main trajectories for the development of childhood cancer, two of which have been linked to disease relapse.

5 Jun 2018

New findings shed light on biological mechanisms of gene regulation

A team led by Prof. Stein Aerts uncovers how access to relevant DNA regions is orchestrated in epithelial cells.

5 Jun 2018

Altering bacteria’s genetic code may pave way for long-lasting drugs, shows study

By altering the genetic code in bacteria, researchers at The University of Texas at Austin have demonstrated a method to make therapeutic proteins more stable, an advance that would improve the drugs' effectiveness and convenience, leading to smaller and less frequent doses of medicine, lower health care costs and fewer side effects for patients with cancer and other diseases.

5 Jun 2018

Researchers discover how the heart becomes fully developed

Researchers have discovered how the heart develops from a simple tube into its characteristic S-shape and forms ventricles and atria.

4 Jun 2018

Researchers use 'multiomics' approach to study newborn mouse heart

During the first days of life, the heart of a newborn mouse adapts to entirely new physiological conditions, larger volume loads and an increased energy demand. As a result, fundamental changes occur in the heart. Studies have shown that the heart of neonate mouse retains its ability to effectively repair tissue damage.

4 Jun 2018

Genomic markers can predict lynch syndrome across tumor types

Microsatellite instability and DNA mismatch repair deficiencies can predict Lynch syndrome across tumor types, according to researchers from Memorial Sloan Kettering Cancer Center, who presented this retrospective data analysis in a press conference at the annual meeting of the American Society of Clinical Oncology.

4 Jun 2018

Researchers use magnets to control tiny DNA-based robots

Researchers have devised a magnetic control system to make tiny DNA-based robots move on demand-;and much faster than recently possible.

4 Jun 2018

Free-floating DNA analysis test may help detect early-stage lung cancer

A test that analyzes free-floating DNA in the blood may be able to detect early-stage lung cancer, a preliminary report from the ongoing Circulating Cell-Free Genome Atlas study suggests.

4 Jun 2018

Researchers discover three genes that may have contributed to evolution of large human brain

Three genes involved in nerve cell generation in the brain emerged roughly 3.5 million years ago and may have contributed to the rapid evolution of the large human brain, Howard Hughes Medical Institute (HHMI) Investigator David Haussler and colleagues report on May 31, 2018, in the journal Cell.

1 Jun 2018

Study reveals 133 genetic variants that may improve risk prediction for glaucoma

Researchers funded by the National Eye Institute have identified 133 genetic variants that predict with 75-percent accuracy a person's risk for developing glaucoma related to elevated pressure within the eye.

31 May 2018

Research sheds light on genetic characteristics of Indonesia's rotavirus

Rotavirus A causes acute diarrhea in young children, and infects both animals and humans worldwide. A Japanese research group has found that the acute gastroenteritis infecting children in Indonesia between 2015 and 2016 was caused by dominant strains of equine-like G3 rotavirus, genetically different from human strains of the virus.

31 May 2018

Highly stable DNA origami nanostructures may pave way for a plethora of biomedical applications

The DNA origami technique is a widely used method for making complex, yet well-defined nanostructures, with applications in biophysics, molecular biology, as well as drug and enzyme delivery.

31 May 2018

New RNA deletion tool could help create drugs that correct genetic diseases

As scientists gain insights into which genes drive diseases, they are pursuing the next logical question: Can gene editing technologies be developed to treat or even cure those diseases? Much of that effort has focused on developing technologies such as CRISPR-Cas9, a protein-based system.

30 May 2018

New study shows that epigenetic silencing of genes limits eye development of cave fish

Loss of eye tissue in blind cavefish (Astyanax mexicanus), which occurs within a few days of their development, happens through epigenetic silencing of eye-related genes, according to a study led by the National Institutes of Health. Epigenetic regulation is a process where genes are turned off or on, typically in a reversible or temporary manner.

29 May 2018

Researchers develop innovative tool for female reproductive genetics

The fruit fly Drosophila melanogaster is a powerful model organism for studying animal and human development and disease. It is low cost, generates rapidly, and there are many tools to genetically modify its cells.

29 May 2018