Genomics

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Stowers researchers solve 3D structure of critical protein complex using microscopy techniques

Researchers at the Stowers Institute for Medical Research have solved the three-dimensional structure of a complex that is essential for the correct sorting of chromosomes into eggs and sperm during reproductive cell division or meiosis.

2 Aug 2017

Research shows great potential of embryonic gene editing to prevent inherited diseases

Scientists have, for the first time, corrected a disease-causing mutation in early stage human embryos with gene editing.

2 Aug 2017

Expert outlines pros and cons of ordering various genetic tests

The amount of information gathered via next-generation sequencing has made the diagnosis of genetic disorders quicker and more accessible to clinicians than ever before, but with expanded testing options come questions about ordering the correct type of testing.

2 Aug 2017

Mathematical modeling can guide design and distribution of genetically modified genes

So, you've genetically engineered a malaria-resistant mosquito, now what? How many mosquitos would you need to replace the disease-carrying wild type? What is the most effective distribution pattern? How could you stop a premature release of the engineered mosquitos?

1 Aug 2017

New partnership uses artificial intelligence methods to develop solutions for preventing early aging

Center for Healthy Aging at the University of Copenhagen today announced a research collaboration with a company specializing in artificial intelligence (AI) to develop solutions for preventing early aging.

1 Aug 2017

Inflammatory biomarkers may help diagnose chronic fatigue syndrome

Researchers have discovered inflammation biomarkers that could help scientists to research, diagnose and even treat chronic fatigue syndrome (CFS). Also referred to as myalgic encephomyelitis, CFS is a poorly-understood condition characterized by profound, long-term tiredness.

1 Aug 2017

Scientist offers evidence to challenge mutation accumulation theory of oncogenesis

What causes cancer? Smoking, certainly, and also things like sun and chemical exposure. Cancer risk also increases with some genetic predispositions and in old age.

1 Aug 2017

DNA-sensing mechanism of innate immune system controls cellular senescence

Cells in the body or in cultures eventually stop replicating. This phenomenon is called "senescence" and is triggered by shortening of telomeres, oxidative stress or genetic damage to the cells, either acute or simply due to the cell growing "old".

31 Jul 2017

Physiology-driven genetic changes have positive influence on brain development

SCIENTISTS in the UK and India have discovered more evidence that positive stimuli in early childhood can benefit the infant brain.

31 Jul 2017

Bringing highly potent cell therapy products to market

There are two main challenges and both relate to manufacturing. The first one is to make sure you can manufacture therapies with reasonable costs and the second one is to make sure that you can balance the capacity you need with the demands.

31 Jul 2017

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

How can six and half feet of DNA be folded into the tiny nucleus of a cell? Researchers funded by the National Institutes of Health have developed a new imaging method that visualizes a very different DNA structure, featuring small folds of DNA in close proximity.

27 Jul 2017

Gene editing technology shines light on rare dyskeratosis congenita

Using the gene editing technology CRISPR, scientists have shed light on a rare, sometimes fatal syndrome that causes children to gradually lose the ability to manufacture vital blood cells.

27 Jul 2017

Researchers uncover 16 genetic markers linked to decreased lifespan

The answer to how long each of us will live is partly encoded in our genome. Researchers have identified 16 genetic markers associated with a decreased lifespan, including 14 new to science. This is the largest set of markers of lifespan uncovered to date.

27 Jul 2017

US scientists make advances in modifying human embryos

American Scientists have managed to edit and improve the DNA of human embryos in an effort to correct the gene defects that cause inherited diseases.

27 Jul 2017

Genetic test that predicts prognosis could benefit early-stage colon cancer patients

Early-stage colon cancer patients could benefit in the future from specific genetic tests that forecast their prognosis and help them make the right decision regarding chemotherapy.

26 Jul 2017

Study provides fresh insights into how the body detects early signs of cancer

Fresh insights into how cells detect damage to their DNA - a hallmark of cancer - could help explain how the body keeps disease in check.

26 Jul 2017

People with family history of bipolar disorder may 'age' more quickly than others

New King's College London research suggests that people with a family history of bipolar disorder may 'age' more rapidly than those without a history of the disease.

26 Jul 2017

Scientists build DNA from scratch using yeast

Researchers are rewriting the yeast genome from scratch as part of a controversial project aiming to create custom-made chunks of DNA codes. One goal of the project is to create codes that can be inserted into cells to alter their function or even improve drug development.

26 Jul 2017

Genetic test to predict IBD severity in children

Inflammatory bowel disease (IBD) is a chronic relapsing inflammation of the gastrointestinal tract with abdominal pain and diarrhea being the most common symptoms. It can be challenging to diagnose as gastrointestinal complaints mimicking IBD are common.

26 Jul 2017

Gene's position on chromosome influences mutations, study shows

Genes do not exist in isolation. Like beads on a string, they sit next to each other on long DNA molecules called chromosomes.

25 Jul 2017

Genomics

Stowers researchers solve 3D structure of critical protein complex using microscopy techniques

Research shows great potential of embryonic gene editing to prevent inherited diseases

Expert outlines pros and cons of ordering various genetic tests

Mathematical modeling can guide design and distribution of genetically modified genes

New partnership uses artificial intelligence methods to develop solutions for preventing early aging

Inflammatory biomarkers may help diagnose chronic fatigue syndrome

Scientist offers evidence to challenge mutation accumulation theory of oncogenesis

DNA-sensing mechanism of innate immune system controls cellular senescence

Physiology-driven genetic changes have positive influence on brain development

Bringing highly potent cell therapy products to market

DNA-protein structure more diverse and flexible chain than previously thought, study reveals

Gene editing technology shines light on rare dyskeratosis congenita

Researchers uncover 16 genetic markers linked to decreased lifespan

US scientists make advances in modifying human embryos

Genetic test that predicts prognosis could benefit early-stage colon cancer patients

Study provides fresh insights into how the body detects early signs of cancer

People with family history of bipolar disorder may 'age' more quickly than others

Scientists build DNA from scratch using yeast

Genetic test to predict IBD severity in children

Gene's position on chromosome influences mutations, study shows

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