Genomics

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Researchers develop new method to make rare cell types and disease patterns visible in tissue

The human body contains more than 30 trillion cells. Until recently, the sheer number of cells in the organism meant that approaches to understanding human diseases and developmental processes based on the analysis of single cells were a futuristic vision.

31 Mar 2023

BGI Genomics and Zentya collaborate to launch first-ever fecal DNA tests for colorectal cancer in Slovakia

BGI Genomics is pleased to announce the launch of COLOTECTTM 1.0 in Slovakia, in collaboration with its local partner, Zentya.

30 Mar 2023

Riboswitch may be the key to advance gene therapy, regenerative medicine

The Okinawa Institute of Science and Technology, in collaboration with Astellas Pharma Inc., has developed a new toolkit that uses small molecules to control the activity of a piece of synthetic RNA, and ultimately regulate gene expression.

30 Mar 2023

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

Engineers at MIT and the University of Massachusetts Medical School have designed a new type of nanoparticle that can be administered to the lungs, where it can deliver messenger RNA encoding useful proteins.

30 Mar 2023

SARS-CoV-2 infection disrupts the RNA modifications, study reports

Coronavirus disease (COVID-19) hijacks parts of infected cells' vital RNA machinery, thereby blocking important functions in the cells. These damaging changes in the RNA can likely be reversed, potentially leading to new drugs against COVID-19, University of Gothenburg researchers show.

29 Mar 2023

COVID-19 activates endogenous retroviruses within our genome

Researchers assess the impact of SARS-CoV-2 infection on endogenous retroviruses of the LTR69 subfamily.

28 Mar 2023

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Excessive cholesterol absorption from intestinal lumen contributes to the pathogenesis of hypercholesterolemia, which is a well-established risk factor for atherosclerotic cardiovascular disease.

28 Mar 2023

Researcher calls evolutionary meddling with genes as "genetic welding"

With CRISPR-Cas9 technology, humans can now rapidly change the evolutionary course of animals or plants by inserting genes that can easily spread through entire populations.

28 Mar 2023

VR imaging system illuminates functional brain network dynamics in autism model

An international research collaboration has developed a VR imaging system that can measure a wide range of neural activity in the cortices of mice during active behavior.

28 Mar 2023

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Looking to learn more from genomics sequencing about DNA mutations and cancer, researchers applied a long-read approach to get a broader genomic view.

27 Mar 2023

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

Researchers from the University of Seville and the Seville Institute of Biomedicine (IBiS), in collaboration with the University of Cambridge, have identified a new role for one of the genes related to hereditary spastic paraplegia.

27 Mar 2023

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Increasing use of genetic testing means people may discover they have a gene variant associated with some types of cardiovascular disease (CVD).

27 Mar 2023

Forward genetic screening reveals important pathways for sleep regulation in C. elegans

Although the regulation of sleep—how much, when, and how sleep occurs—is mainly considered to be controlled by the brain, sleep deprivation also affects the body, and signals from the body can affect sleep.

27 Mar 2023

Microbes living in the human body may be acting as a reservoir for antibiotic resistance

The community of microbes living in and on our bodies may be acting as a reservoir for antibiotic resistance, according to new research from the Earlham Institute and Quadram Institute in Norwich.

27 Mar 2023

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

To develop treatments that may one day entirely rid the body of HIV infection, scientists have long sought to identify all of the places that the virus can hide its genetic code.

27 Mar 2023

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

More than half amount in adult human brain is made up of white matter. Lipid-rich myelin is a special structure formed by oligodendrocytes wrapping neuronal axons to form the major components of white matter.

27 Mar 2023

Circadian rhythms govern cancer progression and metastasis

Your circadian rhythm doesn't just govern your sleeping schedule; it can also impact cancer development, diagnosis, and treatment.

24 Mar 2023

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Induced pluripotent stem cells offer great therapeutic potential and are a valuable tool for understanding how different diseases develop.

24 Mar 2023

Genes known to control eye color are essential for retinal health

Metabolic pathways consist of a series of biochemical reactions in cells that convert a starting component into other products.

23 Mar 2023

Biological BMI measures metabolic health more accurately

Researchers analyze longitudinal and cross-sectional changes in blood analytes associated with variations in body mass index.

23 Mar 2023

Genomics

Researchers develop new method to make rare cell types and disease patterns visible in tissue

BGI Genomics and Zentya collaborate to launch first-ever fecal DNA tests for colorectal cancer in Slovakia

Riboswitch may be the key to advance gene therapy, regenerative medicine

New type of nanoparticle can deliver messenger RNA encoding useful proteins to the lungs

SARS-CoV-2 infection disrupts the RNA modifications, study reports

COVID-19 activates endogenous retroviruses within our genome

NPC1L1-EGFP mice enable researchers to fluorescently visualize, evaluate vesicular endocytosis

Researcher calls evolutionary meddling with genes as "genetic welding"

VR imaging system illuminates functional brain network dynamics in autism model

Using a long-read approach to gain better understanding of DNA mutations in cancer genomes

Researchers discover a new role for one of the genes linked to hereditary spastic paraplegia

New statement suggests next steps to interpret incidentally identified gene variants related to heart disease

Forward genetic screening reveals important pathways for sleep regulation in C. elegans

Microbes living in the human body may be acting as a reservoir for antibiotic resistance

Monocytes may be a stable reservoir of HIV in patients taking antiretroviral therapy

Mea6 elimination in oligodendrocytes impairs white matter structure and lipid content

Circadian rhythms govern cancer progression and metastasis

Screening cultured stem cells for genetic mutations could ensure the accuracy of disease models

Genes known to control eye color are essential for retinal health

Biological BMI measures metabolic health more accurately

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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