Genomics

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10 years of CRISPR genome editing: Advances, limitations, and future potential

In the decade since the publication of CRISPR-Cas9 as a genome editing technology, the CRISPR toolbox and its applications have profoundly changed biological research, enabling advances through applications in plants, animals, and humans.

20 Jan 2023

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Researchers have designed the first 'living medicine' to treat lung infections. The treatment targets Pseudomonas aeruginosa, a type of bacteria which is naturally resistant to many types of antibiotics and is a common source of infections in hospitals.

19 Jan 2023

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Several genes that cause sarcoma have been identified in the first comprehensive genetic map of sarcomas, generated by research led by Omico, the Garvan Institute of Medical Research and UNSW Sydney.

19 Jan 2023

Study reveals how neural networks play a key role in the regulation of circadian rhythms

Circadian rhythms are inherent cycles of approximately 24 hours that regulate various biological processes, such as sleep and wakefulness.

19 Jan 2023

Scientists decipher comprehensive deer tick genome

A University of Maryland-led team of scientists has deciphered the first comprehensive, continuous genome for a parasite responsible for transmitting Lyme disease and other serious infections to hundreds of thousands of Americans yearly.

19 Jan 2023

Comprehensive analysis of genome sequences unravels the elusive origins of bubonic plague

Seeking to better understand more about the origins and movement of bubonic plague, in ancient and contemporary times, researchers at McMaster University, University of Sydney and the University of Melbourne, have completed a painstaking granular examination of hundreds of modern and ancient genome sequences, creating the largest analysis of its kind.

19 Jan 2023

Several genes and individual genetic variations associated with atrial fibrillation discovered

In the largest genetic study of heart arrhythmia to date, researchers led by Kazuo Miyazawa and Kaoru Ito at the RIKEN Center for Integrative Medical Sciences (IMS) in Japan report the discovery of several genes and individual genetic variations that are associated with atrial fibrillation.

19 Jan 2023

Using the power of light to transform analytical workflows in the life sciences

In this interview, we speak to Svea Cheeseman at Refeyn about their SamuxMP products used for the analysis of adeno-associated viruses (AAV) capsids.

From Refeyn 17 Jan 2023

First-ever method for analyzing RNA sequencing data genome-wide using a 'pantranscriptome'

Analyzing a person's gene expression requires mapping their RNA landscape to a standard reference to gain insight into the degree to which genes are "turned on" and perform functions in the body.

16 Jan 2023

Researchers unveil new methods for DNA mosaic recognition

As humans, we each have trillions of cells. And each cell has a nucleus with individual genetic information –DNA – that can mutate to create an abnormality.

13 Jan 2023

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

A new research paper was published in Genes & Cancer on December 14, 2022, entitled, "Slit2 signaling stimulates Ewing sarcoma growth."

13 Jan 2023

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Scientists from the Institut Pasteur, Université Paris Cité, the CNRS and the Collège de France have used paleogenomics to trace 10,000 years of human immune system evolution.

13 Jan 2023

Machine learning tools help unravel why human accelerated regions evolved so quickly

Humans and chimpanzees differ in only one percent of their DNA. Human accelerated regions (HARs) are parts of the genome with an unexpected amount of these differences.

13 Jan 2023

Machine learning tool can enhance the inference of complex cell identities

When genes are activated and expressed, they show patterns in cells that are similar in type and function across tissues and organs.

13 Jan 2023

New breakthrough in understanding the genetic causes of "malformations of cortical development"

Epilepsy is present in 4% of the population, and is among the most common brain disorders in children. Modern medicine can prevent most seizure recurrences, but approximately 20% of patients do not respond to treatment.

12 Jan 2023

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

A new CRISPR-Cas9 approach that targets a detrimental signaling pathway in the heart confers protection from ischemia/reperfusion injury, according to a study in mice.

12 Jan 2023

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Immune checkpoint inhibitors are important medications that boost the immune system's response against various cancers, but some patients' cancer cells are unaffected by the drugs or develop resistance during treatment.

12 Jan 2023

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

The male reproductive system serves as a hotspot for the emergence of new genes. Perhaps that explains why more new mutations are inherited from fathers than from mothers.

12 Jan 2023

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

BioGrad is to open the UK's second largest biobank facility in Liverpool, as part of a £7.6m investment into a new headquarters at Wavertree Technology Park.

From BioGrad 12 Jan 2023

Three genes found to be directly associated with cleft lip and palate

Researchers are finding more genes directly associated with cleft lip and palate.

11 Jan 2023

Genomics

10 years of CRISPR genome editing: Advances, limitations, and future potential

Researchers create the first 'living medicine' to treat drug-resistant lung infections

Study generates a comprehensive genetic map to identify important genes that cause sarcoma

Study reveals how neural networks play a key role in the regulation of circadian rhythms

Scientists decipher comprehensive deer tick genome

Comprehensive analysis of genome sequences unravels the elusive origins of bubonic plague

Several genes and individual genetic variations associated with atrial fibrillation discovered

Using the power of light to transform analytical workflows in the life sciences

First-ever method for analyzing RNA sequencing data genome-wide using a 'pantranscriptome'

Researchers unveil new methods for DNA mosaic recognition

Study uncovers a new role for Slit2 signaling in stimulating Ewing sarcoma growth

Scientists use paleogenomics to trace 10,000 years of human immune system evolution

Machine learning tools help unravel why human accelerated regions evolved so quickly

Machine learning tool can enhance the inference of complex cell identities

New breakthrough in understanding the genetic causes of "malformations of cortical development"

New CRISPR-Cas9 approach confers protection from ischemia/reperfusion injury

Silencing the immune evasion gene enhances cancer cells' susceptibility to immunotherapy

Study reveals why older male fruit flies are more likely to pass mutations onto their offspring

BioGrad to open the UK's second largest biobank facility in Liverpool as part of a £7.6m investment into new headquarters

Three genes found to be directly associated with cleft lip and palate

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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