Genomics

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Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Henry Ford Health research teams are launching a series of clinical studies in partnership with Illumina Inc., a global leader in DNA sequencing and array-based technologies, to assess the impact of comprehensive genomic testing in various disease areas.

11 Apr 2023

Study expands the knowledge about gut viral diversity in healthy infants

Viruses are usually associated with illness. But our bodies are full of both bacteria and viruses that constantly proliferate and interact with each other in our gastrointestinal tract.

11 Apr 2023

Genetically-engineered probiotic could be a new way to reduce alcohol-induced health problems

Excessive alcohol consumption leads to painful hangovers and accompanying headaches, fatigue, and nausea.

11 Apr 2023

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

A study led by Mount Sinai researchers Dr. Bin Zhang, the Willard T.C. Johnson Research Professor of Neurogenetics, and Dr. Christian Forst, an Associate Professor in the Department of Genetics and Genomic Sciences, have identified potential novel receptors for SARS-CoV-2 and unveiled their tissue-specific and age-dependent expression.

11 Apr 2023

Urban light pollution may disrupt winter dormancy period for disease-carrying mosquitoes

A new study's finding that urban light pollution may disrupt the winter dormancy period for mosquitoes that transmit West Nile virus could be considered both good news and bad news.

10 Apr 2023

Using the gene-editing tool to model certain liver tumor subtypes

Mutations in our genes can lead to severe problems, like colon or liver cancer. But cancer is very complex.

10 Apr 2023

Genetic discovery may pave the way for precision medicine approaches to treat depression

A team of scientists at the Medical University of South Carolina (MUSC) has identified a stress-regulated gene that plays a role in the link between long-term stress and a common type of depressive behavior in mice.

7 Apr 2023

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

Gene editing is one of the latest breakthroughs in biology. The widely known CRISPR-Cas gene editing system provided prokaryotes (organisms that lack cell nuclei) an immunity against foreign DNA. Since the discovery of the CRISPR gene editing technology, scientists are revealing the evolution of the CRISPR-Cas proteins from their precursors.

7 Apr 2023

New method estimates mutation risks due to residual radiation from the Fukushima nuclear disaster

Ionizing radiation from nuclear disasters are known to be harmful to the natural environment. The Fukushima Dai-ichi Nuclear Power Plant meltdown that occurred in 2011 is a prominent example of such a disaster in recent memory.

7 Apr 2023

Virginia Tech to study the regulation of genes responsible for cannabinoid biosynthesis

Industrial cultivation of hemp is seeing a massive expansion in the United States due to new federal laws and consumer demand.

6 Apr 2023

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how cancer develops is critical for designing effective, personalized cancer therapies. Researchers have known for years that cancer begins with mutations in certain types of genes.

6 Apr 2023

Understanding how surface factors influence or inhibit biofilm formation in the presence of antibiotics

Similar to how cells within human tissues communicate and function together as a whole, bacteria are also able to communicate with each other through chemical signals, a behavior known as quorum signaling (QS).

5 Apr 2023

SFU researchers study pathogen genes to develop new drugs against bacterial infections

Researchers at Simon Fraser University are studying the genes of superbugs to aid the development of new and effective treatments for drug-resistant bacterial infections.

5 Apr 2023

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

The scientific foundation needed to work on curing a class of cancer-causing mutations is here, in the form of a tool from St. Jude Children's Research Hospital.

5 Apr 2023

Researchers develop a method for making “mini-heart” using pluripotent stem cells

A team at the Technical University of Munich has induced stem cells to emulate the development of the human heart.

5 Apr 2023

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

Mosaic Therapeutics, an oncology therapeutics company dedicated to resolving cancer’s complexity to power new treatments for patients, today announced the close of its $28 million series A funding round.

From Mosaic Therapeutics 4 Apr 2023

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

Prostate cancer tumors harboring BRCA1/2 mutations are exceptionally sensitive to PARP inhibitors, while genomic alterations in other DNA damage response (DDR) genes are less responsive.

4 Apr 2023

New software tool uses genetic data to improve cancer modeling technology

Lifestyle behaviors such as eating well and exercising can be significant factors in one's overall health. But the risk of developing cancer is predominantly at the whim of an individual's genetics.

4 Apr 2023

Unique brain proteins may be critical regulators of body weight

Genetic factors could contribute to up to 50-75% of the variance in body mass index, or BMI, in the population.

4 Apr 2023

Endothelial deletion of the Wt1 gene affects coronary vessel formation and myocardial development

How is the mammals' heart formed? What role do endothelial cells play? Do the same pathways and genes involved in the formation of the embryonic heart also play a role in repair processes?

4 Apr 2023

Genomics

Study to measure the impact of whole genome sequencing in patients with cardiovascular disease

Study expands the knowledge about gut viral diversity in healthy infants

Genetically-engineered probiotic could be a new way to reduce alcohol-induced health problems

SARS-CoV-2 may exploit multiple receptors and pathways across various tissues, age groups

Urban light pollution may disrupt winter dormancy period for disease-carrying mosquitoes

Using the gene-editing tool to model certain liver tumor subtypes

Genetic discovery may pave the way for precision medicine approaches to treat depression

3D structure of a probable precursor to the CRISPR-Cas12 enzyme revealed

New method estimates mutation risks due to residual radiation from the Fukushima nuclear disaster

Virginia Tech to study the regulation of genes responsible for cannabinoid biosynthesis

Researchers discover and characterize a novel protein involved in tumor suppression mechanism

Understanding how surface factors influence or inhibit biofilm formation in the presence of antibiotics

SFU researchers study pathogen genes to develop new drugs against bacterial infections

St. Jude computational biologists characterize the full spectrum of oncogenic fusions in pediatric cancer

Researchers develop a method for making “mini-heart” using pluripotent stem cells

Mosaic Therapeutics closes $28m series A funding and appoints Brian Gladsden as CEO

CRISPR screens reveal genetic determinants of PARP inhibition in prostate cancer

New software tool uses genetic data to improve cancer modeling technology

Unique brain proteins may be critical regulators of body weight

Endothelial deletion of the Wt1 gene affects coronary vessel formation and myocardial development

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