Genomics

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Circadian clock can preserve fitness even under long-term nutritional stress

Cells with a functioning molecular clock are better able to adapt to changes in glucose supply and can recover faster from long-term starvation, according to a study published today in eLife.

10 Jan 2023

Developing new tools to accelerate spatial genomics and drug discovery

We speak to Dr. George Emanuel from Vizgen about their new MERSCOPE Platform and how it is accelerating the field of drug discovery by combining both single-cell and spatial genomics.

From Vizgen 10 Jan 2023

Complete Genomics Launches Full Sequencing Platforms at Biotech Showcase™ 2023

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From MGI 10 Jan 2023

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Investigators at Cedars-Sinai have created a unique and detailed molecular profile of endometriosis to help improve therapeutic options for the millions of women suffering from the disease.

9 Jan 2023

Comparison of genetic codes reveals how humans and other mammals lost their hair

Orangutans, mice, and horses are covered with it, but humans aren't. Why we have significantly less body hair than most other mammals has long remained a mystery.

5 Jan 2023

Irish study demonstrates a genetic effect on the response to obesity treatments

Collaborative research between University of Galway and Brunel University London has found that patients with severe and complicated obesity respond differently to a dietary weight loss program based on their genes.

5 Jan 2023

Genotype-first approach uncovers new relationships between genes and clinical conditions

National Institutes of Health researchers have published an assessment of 13 studies that took a genotype-first approach to patient care.

5 Jan 2023

Evolutionary advantage of jumping genes in a fungus discovered

A fungus that infects salamanders contains multiple copies of the same "jumping genes", scientists have discovered.

4 Jan 2023

Recently discovered protein holds potential for the development of new tests for infectious diseases

In a first for the genetic toolset known as CRISPR, a recently discovered protein has been found to act as a kind of multipurpose self-destruct system for bacteria, capable of degrading single-stranded RNA, single-stranded DNA and double-stranded DNA.

4 Jan 2023

Structure and function of a newly discovered CRISPR immune system revealed

In a rare feat, Utah State University biochemists Thomson Hallmark and Ryan Jackson, along with collaborators, published not one, but two seminal papers in a top-tier, peer-reviewed journal this week.

4 Jan 2023

New type of CRISPR gene scissors discovered

Like humans, bacteria and archaea can be attacked by viruses. These microorganisms have developed their own immune defense strategies against their pathogens.

4 Jan 2023

Antibiotic perseverance increases the risk of antibiotic resistance development

Bacterial perseverance is a new phenomenon that helps explain how bacteria adapt to survive antibiotic treatments.

4 Jan 2023

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

A clinical research team from the Department of Paediatrics and Adolescent Medicine and the Department of Obstetrics and Gynaecology, School of Clinical Medicine, LKS Faculty of Medicine, The University of Hong Kong (HKUMed) leads the discovery of applying amniotic fluid cells obtained during 16-24 weeks of pregnancy as a novel sample type for RNA-sequencing in prenatal diagnosis to help more families with tailored clinical management.

4 Jan 2023

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Announcing a new article publication for Zoonoses journal. This study was aimed at screening differentially expressed genes (DEGs) and exploring the potential immune mechanism induced by the Bacillus Calmette-Guerin (BCG) vaccine in a humanized mouse model.

3 Jan 2023

Researchers discover new role of small RNAs in Salmonella infections

Salmonella are food-borne pathogens that infect millions of people a year. To do so, these bacteria depend on a complex network of genes and gene products that allow them to sense environmental conditions.

3 Jan 2023

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

Researchers at Queen Mary University of London have shown that zebrafish can provide genetic baz1b clues to the evolution of social behaviors in humans and domesticated species.

3 Jan 2023

New insights on the circadian clock of Drosophila melanogaster

The higher the temperatures, the faster physiological processes are. But there is an exception: the so-called circadian clock, which regulates the sleep-wake cycle in organisms.

30 Dec 2022

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

High-calorie foods-;high in fat, oil, and sugar-;can taste good but often cause overeating, leading to obesity and major health problems. But what stimulates the brain to cause overeating?

23 Dec 2022

UC San Diego researchers rewrite the textbook on gene regulation

A fundamental principle of molecular biology governs how proteins are made within the cell, which happens in two stages called transcription and translation.

22 Dec 2022

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

After an intrepid, decade-long search, Johns Hopkins Medicine scientists say they have found a new role for a pair of enzymes that regulate genome function and, when missing or mutated, are linked to diseases such as brain tumors, blood cancers and Kleefstra syndrome -; a rare genetic, neurocognitive disorder.

22 Dec 2022

Genomics

Circadian clock can preserve fitness even under long-term nutritional stress

Developing new tools to accelerate spatial genomics and drug discovery

Complete Genomics Launches Full Sequencing Platforms at Biotech Showcase™ 2023

Detailed molecular profile of endometriosis can lead to improved care for millions of women

Comparison of genetic codes reveals how humans and other mammals lost their hair

Irish study demonstrates a genetic effect on the response to obesity treatments

Genotype-first approach uncovers new relationships between genes and clinical conditions

Evolutionary advantage of jumping genes in a fungus discovered

Recently discovered protein holds potential for the development of new tests for infectious diseases

Structure and function of a newly discovered CRISPR immune system revealed

New type of CRISPR gene scissors discovered

Antibiotic perseverance increases the risk of antibiotic resistance development

Study shows the clinical utility of amniotic fluid cells RNA-sequencing in prenatal rare disease diagnosis

Exploring the immune mechanism induced by BCG vaccine in humanized mouse model

Researchers discover new role of small RNAs in Salmonella infections

Zebrafish can provide genetic clues to the evolution of social behaviors in humans, domesticated species

New insights on the circadian clock of Drosophila melanogaster

Study reveals protective role of CRTC1 in stopping people from overeating high-calorie foods

UC San Diego researchers rewrite the textbook on gene regulation

Decade-long search in one-celled, fresh water dwelling organism solves puzzle involved in gene regulation

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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