Genomics

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New approach for efficient engineering of cell and gene therapies

A new approach to the genetic engineering of cells promises significant improvements in speed, efficiency, and reduction in cellular toxicity compared to current methods.

28 Apr 2023

Cryogenic electron microscopy helps visualize structural details of gene regulation process

LMU researchers show detailed displacement process of TBP transcription factor from DNA by Mot1 enzyme.

28 Apr 2023

Study uncovers new clues and raises more questions about CRISPR

CRISPR claimed scientific fame for its ability to quickly and accurately edit genes. But, at the core, CRISPR systems are immune systems that help bacteria protect themselves from viruses by targeting and destroying viral DNA and RNA.

27 Apr 2023

"Deleted" pieces of genetic information may be crucial to the development of humankind

What the human genome is lacking compared with the genomes of other primates might have been as crucial to the development of humankind as what has been added during our evolutionary history, according to a new study led by researchers at Yale and the Broad Institute of MIT and Harvard.

27 Apr 2023

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

Researchers led by Sanford Burnham Prebys assistant professor Lukas Chavez, Ph.D., are leveraging the latest technology to take a never-before-seen look at ependymoma, one of the deadliest pediatric brain tumors.

27 Apr 2023

UC research examines link between genetics and the presence of opioid use disorder

New research out of the University of Cincinnati examines the association between genetics and the presence of opioid use disorder.

27 Apr 2023

Advanced DNA sequencing technique reveals the reason for COVID-19 related sudden child mortality

Sudden, unexplained child mortality is a tragedy; determining the cause of death is important for improving healthcare and providing loved ones with closure.

27 Apr 2023

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Usher Syndrome type 1F is a rare but severe genetic disease that causes deafness, lack of balance, and progressive blindness.

26 Apr 2023

Researchers shed light on the genetics behind facial changes in Down syndrome

Researchers at the Francis Crick Institute, King's College London and University College London have shed light on the genetics behind changes in the structure and shape of the face and head in a mouse model of Down Syndrome.

26 Apr 2023

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

To highlight how far the field of genetics has come, we spoke with Dr. Francis Collins, the leader of the Human Genome Project about his incredible career in genetics.

25 Apr 2023

Researchers pioneer a new method for fast miRNA amplification and detection

In the early 1990s, scientists who were studying the development of a roundworm identified a small RNA molecule that regulated the expression of specific genes.

24 Apr 2023

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

Researchers have developed a new method to distinguish between cancerous and healthy stem cells and progenitor cells from samples of patients with acute myeloid leukemia (AML), a disease driven by malignant blood stem cells that have historically been difficult to identify.

24 Apr 2023

New genome editing technology achieves efficient and precise large DNA insertions

GAO Caixia's group from the Institute of Genetics and Developmental Biology of the Chinese Academy of Sciences has developed a new genome editing technology that achieves efficient and precise targeted insertion of large DNA segments in plants.

24 Apr 2023

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

Despite the increasing use of genomic sequencing in clinical practice, interpreting rare genetic mutations, even among well-studied disease genes, remains difficult.

21 Apr 2023

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

An extra copy of a gene that controls synapse formation in the cortex causes excessive inhibitory signaling and may contribute to Down syndrome, according to a new study publishing April 20th in the open access journal PLOS Biology by Bing Ye of the University of Michigan, US, and colleagues.

21 Apr 2023

Researchers develop a new powerful resource to study extracellular RNA

An international team led by researchers at Baylor College of Medicine with the National Institutes of Health Extracellular RNA Communication Consortium and the Bogdan Mateescu laboratory at the ETH Zürich and University of Zürich has developed a new powerful resource to study extracellular RNA (exRNA), a novel form of cell-to-cell communication.

20 Apr 2023

Genomics

New approach for efficient engineering of cell and gene therapies

Cryogenic electron microscopy helps visualize structural details of gene regulation process

Study uncovers new clues and raises more questions about CRISPR

"Deleted" pieces of genetic information may be crucial to the development of humankind

3D genome mapping may lead to the treatment of deadliest pediatric brain tumors

UC research examines link between genetics and the presence of opioid use disorder

Advanced DNA sequencing technique reveals the reason for COVID-19 related sudden child mortality

Researchers take key step toward developing a gene therapy for Usher syndrome type 1F

Researchers shed light on the genetics behind facial changes in Down syndrome

The Wonder of DNA: Reflections from Dr. Francis Collins on the 20th Anniversary of the Human Genome Project

Researchers pioneer a new method for fast miRNA amplification and detection

New computational method identifies routes of cellular differentiation in acute myeloid leukemia

New genome editing technology achieves efficient and precise large DNA insertions

New tool offers high accuracy in the interpretation of genetic mutations in disease genes

An extra gene causes excessive inhibitory connections in the neocortex of Down syndrome mouse models

Researchers develop a new powerful resource to study extracellular RNA

Gene therapy approach can decrease intraocular pressure in pre-clinical models of glaucoma

Study reveals a previously unknown mechanism for DNA folding

U-M researcher launches new project to identify the full range of RNA building blocks inside human cells

Precise genome editing approach can correct mutation that causes sickle cell disease

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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