Genomics

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ASU scientists discover an unusual RNA biogenesis pathway

For the very first time, a study led by Julian Chen and his group in Arizona State University's School of Molecular Sciences and the Biodesign Institute's Center for the Mechanism of Evolution, has discovered an unprecedented pathway producing telomerase RNA from a protein-coding messenger RNA (mRNA).

3 Oct 2022

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

BGI Genomics, in collaboration with Southwest University, the State Key Laboratory of Silkworm Genome Biology, and other partners, has constructed a high-resolution pangenome dataset representing almost the entire genomic content in a silkworm.

30 Sep 2022

“Mystery gene” matures a main component of the cell skeleton

"I'm a professional pin-in-a-haystack seeker," geneticist Thijn Brummelkamp responds when asked why he excels at tracking down proteins and genes that other people did not find, despite the fact that some have managed to remain elusive for as long as forty years.

29 Sep 2022

Study offers a new glimpse at how DNA variants can impact the lifespan

In a new study of more than 3,000 genetically diverse mice in a multicenter, multiyear project on healthy aging, Maroun Bou Sleiman and colleagues identified several genetic loci that correlate with longevity, offering a new glimpse at how DNA variants can impact the lifespan.

29 Sep 2022

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Yourgene Health plc (“Yourgene”, AIM: YGEN), a leading international molecular diagnostics group, today announced it has received Health Sciences Authority (HSA) approval for its IONA® Nx NIPT Workflow in Singapore.

From Yourgene Health 29 Sep 2022

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Researchers from Barts Cancer Institute (BCI) at Queen Mary University of London, the Italian Institute for Genomic Medicine, and the University of Milan have identified a novel role for a cancer-causing gene in controlling an important genetic process that underpins genetic variation in prostate cancer.

27 Sep 2022

Novel CRISPR-based method benefits further cancer studies

Researchers have identified a mechanism by which an oncogene commonly activated in cancer patients affects the growth rate of cells.

27 Sep 2022

NIH launches new program to better understand the function of every human gene

The National Institutes of Health is launching a program to better understand the function of every human gene and generate a catalog of the molecular and cellular consequences of inactivating each gene.

27 Sep 2022

Study shows how a common epigenetic modification can be transmitted across multiple generations

Without altering the genetic code in the DNA, epigenetic modifications can change how genes are expressed, affecting an organism's health and development.

27 Sep 2022

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

Beckman Coulter Life Sciences, a global leader in laboratory automation and innovation, announces its continuing commitment to the next generation of researchers and scientists with a call for registrations for its SPRI Grants for Genomic Research.

From Beckman Coulter Life Sciences 27 Sep 2022

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Researchers at the University of California San Diego have for the first time discovered a pattern of DNA mutations that links bladder cancer to tobacco smoking.

27 Sep 2022

Advanced software tool uncovers new cancer-driving genes

An advanced software tool for analyzing DNA sequences from tumor samples has uncovered likely new cancer-driving genes, in a study led by Weill Cornell Medicine researchers.

26 Sep 2022

Researchers identify key gene network responsible for severe tooth enamel defects

Mutations in a certain molecule result in severe damage in the structure and mineral composition of tooth enamel in mice, according to a study conducted at the UZH Center of Dental Medicine.

26 Sep 2022

Viruses exploit ability to sense the environment to maximize their infective yield

New UMBC-led research in Frontiers in Microbiology suggests that viruses are using information from their environment to "decide" when to sit tight inside their hosts and when to multiply and burst out, killing the host cell. The work has implications for antiviral drug development.

23 Sep 2022

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Tiny nets woven from DNA strands can ensnare the spike protein of the virus that causes COVID-19, lighting up the virus for a fast-yet-sensitive diagnostic test – and also impeding the virus from infecting cells, opening a new possible route to antiviral treatment, according to a new study.

23 Sep 2022

Coral genome reveals an alternative pathway for cysteine biosynthesis

Model animals, such as mice and fruit flies, have provided scientists with powerful insights into how cellular biology works. However, model animals are really just a guide, and it can be risky to generalize findings across animals from studying a selection of model organisms.

23 Sep 2022

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

In a new paper, University of California, Irvine researchers explain how precision genome editing agents have enabled precise gene correction and disease rescue in inherited retinal diseases (IRDs).

23 Sep 2022

Scientists create new tool to identify genomic safe harbor sites in specific tissues

Scientists at St. Jude Children's Research Hospital have created a tool that can find safe places to introduce genes into human DNA.

22 Sep 2022

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Two scientists at the David Geffen School of Medicine at UCLA have been awarded nearly $10 million from the National Institutes of Health's Brain Research Through Advancing Innovative Neurotechnologies (BRAIN) Initiative for research projects that aim to shed light on the developing brain's cellular infrastructure to better understand brain disorders.

22 Sep 2022

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

With a five-year, $126 million grant from the National Institutes of Health, a team led by Salk Institute scientists has launched a new Center for Multiomic Human Brain Cell Atlas.

22 Sep 2022

Genomics

ASU scientists discover an unusual RNA biogenesis pathway

High-resolution pangenome dataset provides genetic insights into domestic and wild silkworm

“Mystery gene” matures a main component of the cell skeleton

Study offers a new glimpse at how DNA variants can impact the lifespan

Yourgene Health Receives HSA approval for IONA Nx NIPT Workflow in Singapore

Research reveals how cancer-causing gene influences genetic variability in prostate cancer

Novel CRISPR-based method benefits further cancer studies

NIH launches new program to better understand the function of every human gene

Study shows how a common epigenetic modification can be transmitted across multiple generations

Investing in the next generation of researchers, Beckman Coulter Life Sciences announces call for grant applications

New machine learning tool discovers mutational signature that links bladder cancer to tobacco smoking

Advanced software tool uncovers new cancer-driving genes

Researchers identify key gene network responsible for severe tooth enamel defects

Viruses exploit ability to sense the environment to maximize their infective yield

DNA nets effectively target the spike protein and detect COVID-19 virus at very low levels

Coral genome reveals an alternative pathway for cysteine biosynthesis

Genome editing approaches enable precise gene correction and disease rescue in inherited retinal diseases

Scientists create new tool to identify genomic safe harbor sites in specific tissues

UCLA scientists receive $10 million to shed light on the developing brain's cellular infrastructure

Salk scientists launch a new Center for Multiomic Human Brain Cell Atlas with $126 million NIH grant

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