Histology & Microscopy

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Advances in BioAFM

AFM is quite a versatile technique and we see a great potential of this technology for life science applications. It is still fairly new in Bio community, however very well accepted not only as imaging tools but as a versatile instrument for nanomechanical measurements.

From Bruker Nano Surfaces and Metrology 19 Dec 2017

Pittcon Release eBook Featuring the Latest Scientific Advances

Ahead of the 2018 conference and expo, Pittcon has released an eBook that highlights the latest advances in a range of scientific disciplines. It is an ‘ultimate compilation’ of scientific articles and interviews with some of the worlds leading scientists.

From Pittcon 19 Dec 2017

Spatial deconvolution of marker expression in whole heart subjected to ischemia-reperfusion

When a coronary artery is obstructed by atheroma, blood flow is depressed or even arrested. This causes hypoxia of cardiac cells associated with the deprivation of nutrients. In clinic, the first objective is to restore blood flow. However, this is associated with a burst in oxidation of cellular proteins and lipids. This oxidation enhances cell death and participates to the so-called reperfusion injury.

From Logos Biosystems 18 Dec 2017

Live-cell microscopy reveals internal forces that direct cell migration

Two new studies conducted at the Marine Biological Laboratory (MBL) indicate the way by which cells react to internal forces when they orient, gain traction, and migrate in a particular direction.

11 Dec 2017

Phasefocus™ appoints Chinese distributor as part of Asia expansion

Phasefocus continues to increase its global international profile with the appointment of Nuohai Life Sciences as the company’s exclusive distributor for mainland China, Hong Kong and Macau.

From Phase Focus Limited 11 Dec 2017

Biological Applications of AFM

An interview with Samuel Lesko, European Applications Manager, Bruker Nano Surfaces conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 5 Dec 2017

Overcoming Challenges of Assays of Complex Cellular Models with Real-Time Live-Cell Analysis

There's a continued drive towards making in vitro assays ever more translational towards in vivo models and ultimately the clinic. This ties in with the resurgence of phenotypic screening and is a response to the perceived poor translation of the traditional simple cell-based assays, often developed to study just single protein targets.

From Sartorius 5 Dec 2017

Researchers release open-source dataset offering instructions to build smartphone microscope

Add one more thing to the list of tasks your smartphone can perform. University of Houston researchers have released an open-source dataset offering instructions to people interested in building their own smartphone microscope.

30 Nov 2017

New microscope optimized to perform studies using optogenetic techniques

A newly developed microscope is providing scientists with a greatly enhanced tool to study how neurological disorders such as epilepsy and Alzheimer's disease affect neuron communication.

29 Nov 2017

Study employs dye to identify lost ocean microplastics

A study conducted at the University of Warwick found a novel, inexpensive and innovative technique using a fluorescent dye to effectively identify the smallest microplastics in oceans, which go largely undetected and are potentially harmful.

28 Nov 2017

Using AFM to characterize cancer cells

An interview with Dr. Jim Gimzewski, UCLA conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 28 Nov 2017

Probing living cells with AFM

An interview with Prof. David Alsteens, Université Catholique de Louvain conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 21 Nov 2017

Simple mirror technique boosts the performance of diSPIM, study says

Researchers from the Marine Biological Laboratory (MBL) have significantly improved the efficiency, resolution, and speed of a light-sheet microscope, by using a simple mirror technique and not-so-easy computational analysis, with a wide range of applications for better imaging of embryos and live cells.

20 Nov 2017

Study records video of colliding organic nanoparticles

A new study conducted at the Northwestern University, published today in the Journal of the American Chemical Society, captured a video of organic nanoparticles colliding and fusing together, a breakthrough in nanotechnology.

20 Nov 2017

Applying AFM to study the viscoelastic properties of cells

An interview with Prof. Manfred Radmacher, Universität Bremen conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 16 Nov 2017

Olympus IXplore SpinSR10 imaging system enables researchers to observe fine details in live cells

With resolving power that surpasses the limits of conventional optical microscopes, the Olympus IXplore SpinSR10 imaging system balances speed, resolution, and efficiency in a single, flexible platform.

From Evident Corporation - Life Sciences 15 Nov 2017

Olympus’ 18-megapixel SC180 camera produces clear, crisp images at all magnifications

Optimized for sharing, documenting and publishing, the fast 18-megapixel SC180 camera uses the full optical resolution of the microscope and produces clear, crisp images at all magnifications.

From Evident Corporation - Life Sciences 15 Nov 2017

Using AFM to study cancer cells

An interview with Prof. Hermann Schillers, Universität Münster conducted by April Cashin-Garbutt, MA (Cantab).

From Bruker Nano Surfaces and Metrology 14 Nov 2017

Scientists improve resolution of optical microscope using mirrored coverslip and computer algorithms

Researchers from the National Institutes of Health and the University of Chicago improved the speed, resolution, and light efficiency of an optical microscope by switching from a conventional glass coverslip to a reflective, mirrored coverslip and applying new computer algorithms to process the resulting data.

13 Nov 2017

New optical microscopy technique reveals dimerization of ‘toll-like receptors’

The surface of every cell contains receptors that react to external signals similar to a "gate". In this way, the cells of the innate immune system can differentiate between friend and foe partly through their "toll-like receptors" (TLRs).

3 Nov 2017