Histology & Microscopy

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New approach reveals spongelike properties of the skin’s dermis layer

Hydraulic permeability-;the ability of water to move in all directions through a multicellular complex tissue-;allows skin to maintain turgor and appear plump.

22 Aug 2023

The ancestral origins of the cardiovascular system

Coronary arteries are a vital part of the human heart, providing it with oxygen-rich blood so that it can work.

22 Aug 2023

Researchers decipher the mode of action of new antibiotic

More and more bacterial pathogens are developing resistance. There is an increasing risk that common drugs will no longer be effective against infectious diseases.

22 Aug 2023

Scientists map how worm brain encodes behavior

To understand the full relationship between brain activity and behavior, scientists have needed a way to map this relationship for all of the neurons across a whole brain-;a so far insurmountable challenge.

21 Aug 2023

Scientists capture first images of ribosome-modifying enzymes in action

Bacteria draw from an arsenal of weapons to combat the drugs intended to kill them. Among the most prevalent of these weapons are ribosome-modifying enzymes.

14 Aug 2023

Cryo-EM structures and functions of potent bispecific antibodies against multiple Omicron sublineages

Researchers characterizes the structures and functions of potent bispecific antibodies against multiple Omicron subvariants using Cryo-EM.

3 Aug 2023

New technique revolutionizes protein-ligand interaction studies

Raman spectroscopy -; a chemical analysis method that shines monochromatic light onto a sample and records the scattered light that emerges -; has caused frustration among biomedical researchers for more than half a century.

28 Jul 2023

Cryo-EM study elucidates 3D structure and molecular mechanism of platelet drug transporter

A research team led by Prof. CHEN Yuxing and Prof. ZHOU Cong from the University of Science and Technology of China (USTC) of the Chinese Academy of Sciences (CAS) recently utilized single-particle cryogenic electron microscopy (cryo-EM) to decipher the 3D structure and molecular mechanism of the platelet drug transporter ABCC4.

28 Jul 2023

New nano-immune magnetic bead developed for efficient SARS-CoV-2 virus detection

A more efficient way to test SARS-CoV-2 Virus was developed recently by a research team led by Professor WANG Junfeng from Hefei Institutes of Physical Science (HFIPS), Chinese Academy of Science (CAS).

28 Jul 2023

Scientists map 3D structure of kappa opioid receptor

Opioids remain the most potent and effective pain relievers in medicine, but they're also among the most addictive drugs that can halt a person's ability to breathe during an overdose -; which can be deadly.

27 Jul 2023

Scientists unravel step-by-step activation process of protein with deep evolutionary history

Scientists have unraveled the step-by-step activation process of a protein with a deep evolutionary history in all domains of life, opening the door to harnessing its functions for use as a biotechnology tool.

26 Jul 2023

Scientists discover new details about RNA editing in single-celled, disease-causing parasite

As molecular biologists at Boston University and as husband and wife, Ruslan Afasizhev and Inna Afasizheva, have worked together for decades. Together, they have published dozens of papers on the mechanics of mitochondrial DNA and RNA in a single-celled, disease-causing parasite called Trypanosoma brucei.

19 Jul 2023

AI-based analysis method accelerates study of cell structures

BESSY II's high-brilliance X-rays can be used to produce microscopic images with spatial resolution down to a few tens of nanometers.

18 Jul 2023

BUB1 protein and its kinase activity may regulate EGFR activation

A new research paper was published in Aging (listed by MEDLINE/PubMed as "Aging (Albany NY)" and "Aging-US" by Web of Science) Volume 15, Issue 13, entitled, "Budding uninhibited by benzimidazoles-1 (BUB1) regulates EGFR signaling by reducing EGFR internalization."

18 Jul 2023

DNA origami could be used to create customized virus-like particles

Bioengineers have found a way to program the size and shape of virus particles by combining viral protein building blocks and templates made from DNA.

17 Jul 2023

Scientists investigate a bat virus with pandemic potential

The devastating COVID-19 pandemic occurred when the SARS-CoV-2 virus, native to a species of bats, mutated to infect humans.

10 Jul 2023

LIONESS: A new tool for unraveling mysteries of the brain

Brain tissue is one of the most intricate specimens that scientists have arguably ever dealt with. Packed with currently immeasurable amount of information, the human brain is the most sophisticated computational device with its network of around 86 billion neurons.

10 Jul 2023

Cryo-EM helps decode the molecular architecture of a neural transport protein

Using Cryo-EM, a powerful microscopy technique, researchers at IISc and collaborators have decoded the molecular architecture of a transporter protein controlling the movement of a key neurotransmitter.

6 Jul 2023

Scientists visualize dynamic motion of gene regions on chromosomes

Despite being densely packed to fit into the nucleus, chromosomes storing our genetic information are always in motion.

29 Jun 2023

Three-dimensional epithelial lip area model developed for cosmetics research

KOSÉ Corporation (Headquarters: Chuo-ku, Tokyo; President: Kazutoshi Kobayashi) has developed in collaborative research with Professor Kenji Izumi and his colleagues at Niigata University Graduate School of Medical and Dental Sciences (Faculty of Dentistry) a three-dimensional epithelial model that reproduces the human lip area from the oral mucosa to the lips and surrounding skin, using cell culture.

29 Jun 2023