Histology & Microscopy

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Whole-brain imaging data provides insights into roundworm neural activity

Joint research led by Yu Toyoshima and Yuichi Iino of the University of Tokyo has demonstrated individual differences in and successfully extracted commonalities from the whole-brain activity of roundworms.

15 Mar 2024

New calibration technique enhances accuracy of force measurements in microfluidic environments

A study introduces a novel method for calibrating the spring constant of FluidFM micropipette cantilevers, crucial for the accurate measurement of forces in microfluidic environments.

15 Mar 2024

Revolutionary tool for tracking physical interactions between different cells

One of the fundamental goals of basic biology is understanding how diverse cell types work in concert to form tissues, organs, and organ systems.

6 Mar 2024

New method revolutionizes in vivo brain imaging in awake mice

The human brain has billions of neurons. Working together, they enable higher-order brain functions such as cognition and complex behaviors.

4 Mar 2024

Revolutionizing microscopy with affordable high-resolution techniques

Researchers at the University of Illinois at Urbana-Champaign have shown for the first time that expensive aberration-corrected microscopes are no longer required to achieve record-breaking microscopic resolution.

26 Feb 2024

Microplastics detected in all human placenta samples

A flurry of recent studies has found that microplastics are present in virtually everything we consume, from bottled water to meat and plant-based food.

21 Feb 2024

Unraveling the architecture of poxvirus cores

A recent re-emergence and outbreak of Mpox brought poxviruses back as a public health threat, underlining an important knowledge gap at their core.

6 Feb 2024

Simulations crack code of human egg fertilization

Who hasn't seen it before: the view through the microscope in which a sperm penetrates an egg cell and fertilizes it.

5 Feb 2024

Study reveals the spatial connectivity patterns of mouse hippocampal neurons

A study published in Science on Feb. 1 reported a comprehensive database of single-neuron projectomes consisting of over 10,000 mouse hippocampal neurons, thus revealing the spatial connectivity patterns of mouse hippocampal neurons at the mesoscopic level.

2 Feb 2024

Scientists discover orderly structure hidden within bacterial biofilms

Bacteria are traditionally imagined as single-cell organisms, spread out sparsely over surfaces or suspended in liquids, but in many environments the true bacterial mode of growth is in sticky clusters called biofilms.

2 Feb 2024

Yokogawa introduces CellVoyager High-Content Analysis System CQ3000

The CQ3000 will be showcased at SLAS2024 Boston, MA, February 3-7 with live on-booth demonstrations (booth #485)

From Yokogawa Life Science 2 Feb 2024

New microscopy technology unveils detailed images of brain cancer tissue

Brigham and MIT researchers uncovered never-before-seen details in human brain tissue with new, inexpensive microscopy technology.

1 Feb 2024

Scientists demonstrate way to produce SARS-CoV-2 receptor protein in mouse cells

A team of scientists at the U.S. Department of Energy's (DOE) Brookhaven National Laboratory and Columbia University has demonstrated a way to produce large quantities of the receptor that SARS-CoV-2, the virus that causes COVID-19, binds to on the surface of human cells.

22 Jan 2024

New technique provides an unprecedented view inside the cell's control center

The cell nucleus is considered to be the control center of vital cellular processes, but its material properties continue to puzzle scientists.

18 Jan 2024

Bacterial "freight elevator" unpacked: How pathogens hide from the immune system

Some bacterial membrane transporters work almost like freight elevators to transport substances through the cell membrane into the interior of the cell. The transporter itself spans the bacterial membrane.

8 Jan 2024

Cytonemes: The "express subways" of the developing nervous system

St. Jude Children's Research Hospital scientists found that cytonemes (thin, long, hair-like projections on cells) are important during neural development.

3 Jan 2024

Research reveals how "forever chemicals" damage DNA at the molecular level

Recent research published in the journal Eco-Environment & Health (Volume 2, 2023) reveals groundbreaking insights into how typical PFAAs accelerate the degradation of DNA.

26 Dec 2023

Study reveals how tiny tweaks to actin shape our cells

Tiny things matter – for instance, one amino acid can completely alter the architecture of the cell. Researchers at the Universities of Göttingen and Warwick investigated the structure and mechanics of the main component of the cytoskeleton of the cell: a protein known as actin.

22 Dec 2023

Early embryo DNA replication program reveals unexpected flexibility

The intricate process of duplicating genetic information, referred to as DNA replication, lies at the heart of the transmission of life from one cell to another and from one organism to the next.

20 Dec 2023

Novel adaptations and functions of human LINE-1 revealed by structural analysis and inhibition

Martin Taylor, MD, PhD, a physician investigator in the Department of Pathology at Massachusetts General Hospital and an instructor in Pathology at Harvard Medical School, is the lead corresponding author of a new study in Nature, Structural Analysis and Inhibition of Human LINE-1 ORF2 Protein Reveals Novel Adaptations and Functions.

19 Dec 2023