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Study finds underutilization of warfarin among Kentucky women with AF

Dr. Rabab Mohsin, an internal medicine resident at the University of Kentucky, working with Dr. Alison Bailey of the University of Kentucky Gill Heart Institute, has discovered that the drug warfarin was underutilized in a large study group of women.

14 Dec 2011

Link between maternal pre-pregnant BMI, weight change in pregnancy and offspring birthweight

A new study published in the journal Acta Obstetricia et Gynecologica Scandinavica (AOGS) reveals that both pre-pregnant weight (body mass index, BMI) and weight gain in pregnancy are important predictors of babies' birthweight. This is important since high birthweight may also predict adult overweight.

14 Dec 2011

Study reveals key role of melatonin receptor in sleep regulation

A team from the Research Institute of the McGill University Health Centre (RI-MUHC) and McGill University has made a major breakthrough by unraveling the inner workings of melatonin, also known as the "sleep hormone."

14 Dec 2011

Study to evaluate effectiveness of cognitive behavioral therapy for BDD

Rhode Island Hospital has received a grant for more than $1.5 million from the National Institute of Mental Health (NIMH) for a 5-year study on treatment for Body Dysmorphic Disorder (BDD). Led by Katharine A. Phillips, M.D., director of the BDD Program at Rhode Island Hospital and an internationally known expert in BDD, the study will examine the effectiveness of cognitive behavioral therapy versus supportive psychotherapy for the treatment of people with BDD.

14 Dec 2011

Microneedle-based sensors can detect real-time chemical changes in the body

Researchers from North Carolina State University, Sandia National Laboratories, and the University of California, San Diego have developed new technology that uses microneedles to allow doctors to detect real-time chemical changes in the body - and to continuously do so for an extended period of time.

14 Dec 2011

New substance can replace nucleoside thymidine in DNA biosynthesis

Interactions of biological macromolecules are the central bases of living systems. Biological macromolecules are synthesized in living cells by linking many small molecules together. Naturally occurring macromolecules include genetic materials (DNA) and proteins. A detailed understanding of the synthesis of these macromolecules in whole animals is a basic requirement for understanding biological systems, and for the development of new therapeutic strategies.

14 Dec 2011

JDRF initiates enrollment in metformin clinical study for type 1 diabetes

JDRF-funded researchers have begun enrolling adult patients with type 1 diabetes (T1D) in the REMOVAL study, to test whether metformin-a drug commonly used to treat type 2 diabetes-could help prevent or reduce the risk of cardiovascular complications in people with T1D.

14 Dec 2011

Mimicking periosteum to heal traumatic bone injury

A manmade package filled with nature's bone-building ingredients delivers the goods over time and space to heal serious bone injuries faster than products currently available, Cleveland researchers have found.

14 Dec 2011

Unexplained kidney disease affecting rural workers across Central America, PRI's 'The World' reports

PRI's "The World" reports on an epidemic of an unexplained kidney disease that is affecting rural workers across Central America, writing, "[I]t's the second biggest cause of death among men in El Salvador, and in Nicaragua it's a bigger killer of men than HIV and diabetes combined," and "the latest theory is that the victims are literally working themselves to death."

14 Dec 2011

Individuals with mood and anxiety disorders may be more likely to abuse opioids

Individuals suffering from mood and anxiety disorders such as bipolar, panic disorder and major depressive disorder may be more likely to abuse opioids, according to a new study led by researchers from the Johns Hopkins Bloomberg School of Public Health. They found that mood and anxiety disorders are highly associated with non-medical prescription opioid use.

14 Dec 2011

Researchers identify interactive pathway that regulates cancer metastasis

Finding ways to counteract or disrupt the invasive nature of cancer cells, called "metastasis," has been a long-term goal of cancer researchers. Now, researchers at Moffitt Cancer Center in Tampa, Fla., have identified an interactive pathway that regulates metastases in some cancers that may be vulnerable to chemical targeting in order to prevent cancer cell proliferation and tumor growth.

14 Dec 2011

Bronx churches, Montefiore partner to fight against hypertension

Montefiore Medical Center is sponsoring screenings and educational workshops at churches in the Bronx in order to help reduce the risk of cardiovascular disease in congregants who are identified with hypertension. Congregants learn about hypertension, medication management, weight control, healthy cooking habits and perform yoga exercises to reduce stress.

14 Dec 2011

People with myotonic muscular dystrophy more likely to develop cancer

People who have the most common type of adult muscular dystrophy also have a higher risk of getting cancer, according to a paper published today in the Journal of the American Medical Association.

14 Dec 2011

Top five tips for easy breathing during holiday season

Getting out the boxes of holiday decorations from years gone by is a time-honored tradition. But in addition to stirring up memories, it also stirs up allergies. "The dust from the boxes and on the decorations that have been packed away in dank basements or dusty attics is triggering reactions in my allergy and asthma patients," said Joseph Leija, MD, allergist at Gottlieb Memorial Hospital.

14 Dec 2011

Positive results from Aestus' ATx08-001 Phase II study on post-herpetic neuralgia

Aestus Therapeutics, Inc. today reported positive results from a Phase II clinical study evaluating the efficacy of its novel neuropathic pain therapeutic, ATx08-001, in the treatment of post-herpetic neuralgia.

14 Dec 2011

Economic impact of PTSD in Northern Ireland

Northern Ireland has the world's highest recorded rates of Post Traumatic Stress Disorder (PTSD), ahead of war-hit regions such as Israel and Lebanon, at a yearly cost to the public purse of around £175 million, according to a major report by University of Ulster psychologists and Omagh-based trauma treatment experts.

14 Dec 2011

ImmusanT secures $20M in Series A financing

ImmusanT, Inc. announced today it has raised $20 million in Series A financing from Vatera Healthcare Partners LLC to advance development of the biotechnology company's immunotherapeutic vaccine Nexvax2, companion diagnostic and monitoring tool for celiac disease.

14 Dec 2011

Microwave ablation therapy may be safe, effective for pulmonary metastases

Covidien, a leading global provider of healthcare products, today announced that Radiology, the monthly journal of the Radiological Society of North America, has published a new research study led by Prof. Thomas J. Vogl, MD, entitled, "Microwave Ablation Therapy: Clinical Utility in Treatment of Pulmonary Metastases."

14 Dec 2011

Standard chemotherapy regimen may increase survival rates in limited stage Hodgkin's lymphoma patients

New research led by the NCIC Clinical Trials Group (CTG) at Queen's University has proven patients with limited stage Hodgkin's lymphoma have a better chance of long-term survival if they undergo a standard chemotherapy regimen as opposed to radiation-based treatment.

14 Dec 2011

Mandatory screening helps identify more athletes with SCT

In response to a lawsuit after a college football player died from complications due to sickle cell trait (SCT) during a workout, the NCAA implemented mandatory SCT screening of all Division I student-athletes.

14 Dec 2011