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Scientists uncover how bacterium responsible for periodontal disease worsens RA

Does gum disease indicate future joint problems? Although researchers and clinicians have long known about an association between two prevalent chronic inflammatory diseases - periodontal disease and rheumatoid arthritis - the microbiological mechanisms have remained unclear.

13 Sep 2013

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

New research in mouse models suggests that treatment with antioxidants may help reduce behavioral issues linked to the genetic nervous system disorder Neurofibromatosis 1 (NF1) and an associated condition called Costello syndrome.

12 Sep 2013

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Since the sequence map of the human genome, the cost of sequencing the genome of an individual has fallen rapidly. This has resulted in a tremendous increase in the amount of human genomic data available to the international research community for the advancement of biomedical research. Yet, there is an absence of international mechanisms to support researchers in ensuring ethical and legal interoperability. In addition, the multiplicity and diversity of laws, standards and policies on sharing and accessing genetic and medical data represent major hurdles to international collaboration.

12 Sep 2013

Merlin and Hippo proteins interact to begin chain of events that control tissue growth

Johns Hopkins researchers have figured out the specific job of a protein long implicated in tumors of the nervous system. Reporting on a new study described in the Sept. 12 issue of the journal Cell, they detail what they call the "matchmaking" activities of a fruit fly protein called Merlin, whose human counterpart, NF2, is a tumor suppressor protein known to cause neurofibromatosis type II when mutated.

12 Sep 2013

Orangutans may share an underlying conceptual process with humans

The ability to form a general concept that connects what we know about the members of a category allows humans to respond appropriately when they encounter a novel member of that category. At an early age, children form categories to, for example, differentiate animals from inanimate objects and to differentiate dogs from cats. New research shows that other apes may form similar categories to represent different types of animals.

12 Sep 2013

Research holds promise for developing treatments for retinitis pigmentos

One of the leading causes of inherited blindness in humans, retinitis pigmentosa, is analogous to retinal dystrophies that lead to blindness in dogs. Because of their similarities, identifying gene mutations underlying several types of canine retinal dystrophies has suggested courses for research on RP in humans. These advances are significant for both humans and dogs.

12 Sep 2013

BioTek's new MultiFlo FX Microplate Dispenser combines dispensing and washing in one platform

BioTek's new MultiFlo FX Microplate Dispenser offers up to four independent reagent dispensers and a washer in one compact and modular platform to simplify and automate microplate-based liquid handling processes, thus saving time and reducing reagent costs.

12 Sep 2013

BioTek's BioStack 4 Microplate Stacker provides walk-away automation for routine microplate processes

BioTek introduces the BioStack 4 Microplate Stacker, providing walk-away automation for routine microplate-based processes including cell-based assays and any application requiring automated plate delidding and re-lidding.

12 Sep 2013

BioTek's Cytation3 Cell Imaging Multi-Mode Reader recognized by SelectScience

For the second year in a row, BioTek Instruments was announced as winner of the SelectScience "Scientists' Choice Award for Best Drug Discovery Product". The award was given for BioTek's new Cytation3 Cell Imaging Multi-Mode Reader, and was announced at ELRIG Drug Discovery in Manchester, UK.

12 Sep 2013

Astragaloside IV contributes to sciatic nerve regeneration

Astragaloside IV, the main component of the traditional Chinese medicine astragalus membra-naceus, has been shown to inhibit inflammation, oxidation, and apoptosis, and exerts immu-noregulatory effects. Xiaohong Zhang and colleagues from School of Pharmacutical Sciences, Jilin University investigated whether astragaloside IV could promote the repair of injured sciatic nerve.

12 Sep 2013

Researchers find whether natural food has potential for preventing breast cancer in women

Women who have a higher-than-average risk of developing breast cancer may be concerned about taking cancer prevention drugs because of some of the associated side effects. Researchers at the University of Chicago Medicine are conducting a study to find out whether flaxseed, a natural food, has the potential to be a safe and effective alternative for preventing breast cancer in women.

12 Sep 2013

Study shows anorexia linked to how cholesterol processes

The largest DNA-sequencing study of anorexia nervosa has linked the eating disorder to variants in a gene coding for an enzyme that regulates cholesterol metabolism. The finding suggests that anorexia could be caused in part by a disruption in the normal processing of cholesterol, which may disrupt mood and eating behavior.

12 Sep 2013

Protein plays important role in process of degradation of tumour cells, say researchers

When tumour cells no longer degrade themselves, cancer may develop. Using black skin cancer as an example, Bern Researchers have now shown that a protein plays an important role in the process of degradation of tumour cells. By reactivating this degradation therapeutically, you can virtually force tumours to digest themselves.

12 Sep 2013

Scientists reveal how organic mercury can interfere with vision

More than one billion people worldwide rely on fish as an important source of animal protein, states the United Nations Food and Agriculture Organization. And while fish provide slightly over 7 per cent of animal protein in North America, in Asia they represent about 23 per cent of consumption.

12 Sep 2013

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Whether it's the Ebola virus or Sarin and Ricin, a key to responding to chemical or biological attacks is having effective antidotes at the ready. To accelerate the development of new therapies, Wake Forest Baptist Medical Center's Institute for Regenerative Medicine is leading a unique $24 million federally funded project to develop a "body on a chip" that will be used to develop these countermeasures.

12 Sep 2013

Neuroscientists honored for research into brain's reward and decision-making systems

Maximum reward, minimum punishment: these are the maxims humans and animals often apply when making decisions. A network of nerve cells in the brain conveys gratification.

12 Sep 2013

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Amgen today announced the publication of a biomarker analysis of Vectibix (panitumumab) in combination with FOLFOX, a type of oxaliplatin-based chemotherapy, for the first-line treatment of patients with metastatic colorectal cancer.

12 Sep 2013

Dartmouth researchers find that protein cyclin A plays important role in cell division process

In a study to be published in the journal Nature, two Dartmouth researchers have found that the protein cyclin A plays an important but previously unknown role in the cell division process, acting as a master controller to ensure the faithful segregation of chromosomes during cell division.

12 Sep 2013

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

A family of microRNAs (miR-200) blocks cancer progression and metastasis by stifling a tumor's ability to weave new blood vessels to support itself, researchers at The University of Texas MD Anderson Cancer Center report today in Nature Communications.

12 Sep 2013

Research: New pathway plays role in fighting gut infection

The researchers found virulent E. coli bacteria blocked a pathway that would normally protect the gut from infection. These infections are particularly serious in young children and can result in diarrhoea and other complications such as kidney damage.

12 Sep 2013

Medical Science News

Scientists uncover how bacterium responsible for periodontal disease worsens RA

Research: Treatment with antioxidants may help reduce behavioral issues linked to NF1

P3G and CGP launch International Policy interoperability and data Access Clearinghouse

Merlin and Hippo proteins interact to begin chain of events that control tissue growth

Orangutans may share an underlying conceptual process with humans

Research holds promise for developing treatments for retinitis pigmentos

BioTek's new MultiFlo FX Microplate Dispenser combines dispensing and washing in one platform

BioTek's BioStack 4 Microplate Stacker provides walk-away automation for routine microplate processes

BioTek's Cytation3 Cell Imaging Multi-Mode Reader recognized by SelectScience

Astragaloside IV contributes to sciatic nerve regeneration

Researchers find whether natural food has potential for preventing breast cancer in women

Study shows anorexia linked to how cholesterol processes

Protein plays important role in process of degradation of tumour cells, say researchers

Scientists reveal how organic mercury can interfere with vision

Wake Forest Baptist conducts $24 million project to accelerate development of new therapies

Neuroscientists honored for research into brain's reward and decision-making systems

Biomarker analysis of Vectibix for mCRC published in New England Journal of Medicine

Dartmouth researchers find that protein cyclin A plays important role in cell division process

Elevated miR-200 boosts survival of lung, ovarian, renal, triple-negative breast cancer patients

Research: New pathway plays role in fighting gut infection

Considerations for taking ASO discovery programs into animal models

Neurofilament light as a translational biomarker

How can machine learning accelerate neuroscience behavior studies?

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