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Janssen, Beactica enter drug discovery agreement

Beactica, the leading Swedish fragment-based drug discovery company, today announced that it has entered into an agreement with Janssen Research & Development, a division of Janssen Pharmaceutica NV.

28 Apr 2011

New study sheds light on how sleep-deprived lifestyles might impair brain function

A new study in rats is shedding light on how sleep-deprived lifestyles might impair functioning without people realizing it.

28 Apr 2011

New screening marker can detect pancreatic cancer

Researchers at the University of Michigan Comprehensive Cancer Center have identified a protein that shows distinct changes in structure between pancreatic cancer, non-cancerous diseases and normal blood serum. The protein also changes from early stage pancreatic cancer to advanced disease.

28 Apr 2011

Kava tea may cause kidney failure and muscle breakdown

When a 34-year-old bicyclist was found collapsed on a roadside and rushed to the University of Rochester Medical Center emergency room on the verge of kidney failure and muscle breakdown, doctors were surprised to discover that a trendy tea derived from the kava plant was the cause of his ills.

28 Apr 2011

MIT develops new software to predict complex 3-D DNA structures

While the primary job of DNA in cells is to carry genetic information from one generation to the next, some scientists also see the highly stable and programmable molecule as an ideal building material for nanoscale structures that could be used to deliver drugs, act as biosensors, perform artificial photosynthesis and more.

28 Apr 2011

New nanoparticle imaging agent can help diagnose heart disease, breast cancer

Scientists are reporting development of a process for producing large quantities of a much-needed new imaging agent for computed tomography scans in heart disease, breast cancer and other diseases, and the first evidence that the material is safe for clinical use.

28 Apr 2011

Grapefruit can help reduce weight in obese adults

One-hundred percent grapefruit juice – a dieter's friend? A new study, published in Nutrition & Metabolism, concluded that enjoying a pre-meal snack of grapefruit, grapefruit juice or water as part of a reduced-calorie diet can be part of an effective weight loss strategy for obese adults.

28 Apr 2011

Study clarifies ginkgo's pain-reducing effects

Experiments in rats show that a standardized ginkgo extract—injected either into the spinal canal or directly into the injured area—effectively reduces inflammation and some types of pain, according to a report in the May issue of Anesthesia & Analgesia, official journal of the International Anesthesia Research Society.

28 Apr 2011

Study finds prevalence of low vitamin D status among obese adolescents

A new study from Hasbro Children's Hospital has found that most obese adolescents are lacking in vitamin D.

28 Apr 2011

NHL Alumni, Baycrest team up for brain health research

One of the world's top neuroscience institutes has teamed up with the NHL Alumni on a study that will track the brain health of retired NHL players over several years.

28 Apr 2011

New study reveals a novel gene linked with major depression

A new study reveals a novel gene associated with major depression. The research, published by Cell Press in the April 28 issue of the journal Neuron, suggests a previously unrecognized mechanism for major depression and may guide future therapeutic strategies for this debilitating mood disorder.

28 Apr 2011

Promising pain medication may decrease ability to fight off sepsis

Pain researchers from the Sheikh Zayed Institute for Pediatric Surgical Innovation at Children's National Medical Center have discovered that resiniferatoxin, a drug that has shown early promise as an option for chronic, severe pain sufferers, may decrease the body's ability to fight off bacterial infections, particularly sepsis.

27 Apr 2011

High metabolic rates linked to accelerated aging in humans

A recent study accepted for publication in The Endocrine Society's Journal of Clinical Endocrinology & Metabolism found that higher metabolic rates predict early natural mortality, indicating that higher energy turnover may accelerate aging in humans.

27 Apr 2011

Clinical study: Plant extract can fight effectively against hay fever

Fighting hay fever with a plant extract - this works, as was shown in a clinical study conducted by researchers of the Center of Allergy & Environment of Helmholtz Zentrum München and Technische Universität München.

27 Apr 2011

New discoveries on polycystin-1 can lead to novel kidney disease treatment

Two discoveries at UC Santa Barbara point to potential new drug therapies for patients with kidney disease. The findings are published in this week's issue of the Proceedings of the National Academy of Sciences.

27 Apr 2011

Proteostasis acquires Harvard University's two novel protein target licenses

Proteostasis Therapeutics announced today that it has acquired two exclusive licenses from Harvard University to technologies for enhancing the activity of a key cellular protein clearance mechanism, the ubiquitin-proteasome pathway.

27 Apr 2011

New study sheds light on sleep problems in children with autism

The current prevalence of autism spectrum disorder is alarmingly high. Although there is no cure for autism, it is possible to manage and treat the comorbid medical conditions associated with autism. One of these conditions, sleeping disturbance, can be challenging to treat.

27 Apr 2011

CTNNB1 activation can improve colorectal cancer survival in obese patients

Among obese patients, activation of the protein biomarker CTNNB1 was associated with better colorectal cancer-specific survival and overall survival, whereas post-diagnosis physical activity was associated with better colorectal cancer-specific survival among patients negative for CTNNB1, according to a study in the April 27 issue of JAMA.

27 Apr 2011

LSP announces initial public offering of Life Sciences Fund on NYSE Euronext

LSP Advisory B.V., a group company of LSP, one of Europe's largest and most reputable specialized healthcare and biotechnology investment firms, today announced the initial public offering of the LSP Life Sciences Fund N.V. on NYSE Euronext Amsterdam.

27 Apr 2011

ISCO completes first series of hepatocytes preclinical testing

International Stem Cell Corporation announces successful completion of the first series of preclinical testing of hepatocytes derived in the lab from human parthenogenetic stem cells.

27 Apr 2011