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Taxoxifen combined with dasatinib reverses chemo-resistance in breast cancer cells

Taking a leukemia chemotherapy drug may help breast cancer patients who don't respond to tamoxifen overcome resistance to the widely-used drug, new research from the Kimmel Cancer Center at Jefferson suggests.

2 Aug 2011

Ursodeoxycholic acid could help prevent disturbances in heart's normal rhythm

A synthesised compound which is also found in bear bile could help prevent disturbances in the heart's normal rhythm, according to research published today in the journal Hepatology by a team from Imperial College London.

2 Aug 2011

Scientists design octapeptides to fight drug resistant ovarian cancer cells

Italian and German scientists have designed peptides to target the protein-protein interface of a key enzyme in DNA synthesis crucial for cancer growth. The peptides act by a novel inhibitory mechanism and curb cancer cell growth in drug resistant ovarian cancer cells.

2 Aug 2011

Elsevier launches new interactive feature for life sciences journals

Elsevier, a world-leading provider of scientific, technical and medical information products and services, introduces the Genome Viewer, a new interactive feature on SciVerse ScienceDirect for applicable life sciences journals.

2 Aug 2011

Drink wine to prevent sunburns: Flavonoid research

According to a new Spanish study wine could protect against harmful sunburns. The researchers from the University of Barcelona and the Spanish National Research Council find that a compound found in grapes or grape derivatives may protect skin cells from skin-damaging ultraviolet radiation.

1 Aug 2011

Mathematical model predicts progress of tumors from early stages to metastasis

Researchers from the University of Miami (UM) and the University of Heidelberg in Germany have developed a mathematical model to understand and predict the progress of a tumor, from its early stages to metastasis, in hopes of creating highly personalized treatment strategies for patients who have cancer. The findings are published in Nature's new online journal Scientific Reports.

1 Aug 2011

Nature Biotechnology publishes BGI, GT Life Sciences' study on CHO K1 genome

BGI, the world's largest genomics organization, and GT Life Sciences, Inc., a privately held biotechnology company that utilizes a proven metabolic modeling and experimental platform to drive the discovery and design of new products and processes for the life sciences field, announced today that their collaborative study on the genomic sequence of the Chinese hamster ovary (CHO) K1 cell line was published July 31, 2011 online in Nature Biotechnology.

1 Aug 2011

Artificial nanoparticles have direct effect on heart rate and rhythm

Artificial nanoparticles are becoming increasingly pervasive in modern life. However, their influence on our health and the mechanisms by which they affect the human body remain largely shrouded in mystery.

1 Aug 2011

Stealth presents Bendavia at AHA's Cardiovascular Scientific Sessions

Stealth Peptides Inc. (Stealth), a privately held biopharmaceutical company developing innovative mitochondrial therapies for diseases with unmet medical needs, presented its lead clinical candidate, Bendavia, during the 2011 American Heart Association's (AHA) Cardiovascular Scientific Sessions.

1 Aug 2011

Affymetrix to commercialize four Axiom genotyping arrays for the major populations

Affymetrix, Inc. today announced plans to commercialize four Axiom population-optimized arrays used to analyze 100,000 samples collected from volunteers in one of the nation's largest and most diverse genomics projects funded by the National Institutes of Health.

1 Aug 2011

Researchers identify new plasma membrane sculpting protein

The research group of Professor Pekka Lappalainen at the Institute of Biotechnology, University of Helsinki, has identified a previously unknown mechanism which modifies the structure of plasma membranes in intestinal epithelial cells.

1 Aug 2011

Intensive glycaemic control may negatively affect a person's quality of life

Research published in The Cochrane Library found that the risk of death and cardiovascular disease, such as stroke, was unchanged whether glucose control was intense or conventional.

1 Aug 2011

Scientists reveal genetic region that increases risk of meningioma

Cancer Research UK funded scientists have conducted the first whole-genome scan of the brain tumour meningioma and revealed a genetic region that increases the risk of developing the disease, according to research published in Nature Genetics today.

1 Aug 2011

Myb protein suppression can help eliminate acute myelogenous leukemia

A team of scientists at Cold Spring Harbor Laboratory (CSHL) has laid bare the mechanism behind a phenomenon called oncogene addiction in mice suffering from a form of leukemia that mimics acute myelogenous leukemia (AML) in humans.

1 Aug 2011

Researchers reveal molecular mechanisms responsible for organizing intestinal epithelium

How do cells know where to position themselves and where to accumulate in order to carry out their functions correctly within each organ? Researchers with the Colorectal Cancer Lab at IRB Barcelona have revealed the molecular mechanisms responsible for organizing the intestinal epithelium into distinct comportments, defined by frontiers or territories.

1 Aug 2011

Three new loci linked to asthma susceptibility in Japanese population

Researchers at the RIKEN Center for Genomic Medicine (CGM), together with colleagues at Kyoto University, Tsukuba University, Harvard University, and other medical institutions have identified three new loci associated with susceptibility to adult asthma in the Japanese population.

1 Aug 2011

Researchers reveal novel gene linked with asthma in African-Americans

A new national collaboration of asthma genetics researchers has revealed a novel gene associated with the disease in African-Americans, according to a new scientific report.

1 Aug 2011

Scientists study how nervous system translates sensory information into coordinated motor output

Escape responses are some of the most studied behaviors by neurobiologists who want to understand how the brain processes sensory information. The ability to evade predators plays a vital role in the process of natural selection.

30 Jul 2011

Scientists receive funding to continue research into pathological processes supporting Alzheimer's

Neuroscientists at the University of Bristol have received a major funding boost of -550,000 from the Medical Research Council to continue their research into the pathological processes underpinning Alzheimer's disease, the most common cause of dementia, affecting around 465,000 people in the UK.

30 Jul 2011

RegenoCELL to open new facility in Panama for treatment of congestive heart failure

RegenoCELL Therapeutics, Inc., a leader in adult stem cell therapy, is pleased to announce it is planning to open another state of the art facility in Panama for patients to be treated for congestive heart failure and peripheral artery disease with its autologous stem cell therapy.

30 Jul 2011