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Sanofi-aventis acquires world-wide license for ADC products

Oxford BioTherapeutics today announces that sanofi-aventis has acquired an exclusive world-wide license to one of OBT's internal preclinical antibody programs.

25 Jan 2011

New study on pain-relieving effect of transcutaneous Vagus Nerve Stimulation

The medical device company cerbomed cooperated with the Clinic for Psychiatry and Psychotherapy of the University of Regensburg 2010 on a randomized, controlled study into somatosensory pain processing. The study, lead by Prof. Dr. Peter Eichhammer and Dr. Volker Busch, aimed to judge the pain-relieving effect of transcutaneous Vagus Nerve Stimulation (t-VNS).

25 Jan 2011

Tufts University calls for strategic approach to teach genomic testing in medical school

Genetics in Medicine, the official journal of the American College of Medical Genetics, published this month a paper by Tufts University faculty calling for a moderate, strategic approach to teaching personalized genomic testing in medical school curricula.

25 Jan 2011

Scientists to develop enzyme that protects against nerve agents

Protection against nerve gas attack is a significant component of the defense system of many countries around the world. Nerve gases are used by armies and terrorist organizations, and constitute a threat to both the military and civilian populations, but existing drug solutions against them have limited efficiency.

25 Jan 2011

Glioblastoma's molecular flexibility helps resist nearly all treatment efforts

Glioblastoma, the most common and lethal form of brain cancer and the disease that killed Massachusetts Senator Ted Kennedy, resists nearly all treatment efforts, even when attacked simultaneously on several fronts. One explanation can be found in the tumor cells' unexpected flexibility, discovered researchers at the Salk Institute for Biological Studies.

25 Jan 2011

Composer Fr-d-ric Chopin probably had temporal lobe epilepsy

The composer Fr-d-ric Chopin, who regularly hallucinated, probably had temporal lobe epilepsy throughout his short life, reveals research published online in Medical Humanities. Hallucinations typically feature in seizure disorders, they say.

25 Jan 2011

Cellectis to launch gene specific TAL nucleases

Cellectis bioresearch, a specialist in genome customization and a subsidiary of Cellectis, has today announced that it will launch gene specific TAL nucleases on February 28, 2011.

25 Jan 2011

p38-targeted compounds hold promise for Alzheimer's disease treatment

Linda J. Van Eldik, director of the University of Kentucky Sanders-Brown Center on Aging, has been awarded a $750,000 grant to further her research into a possible treatment for Alzheimer's disease. The grant is from the Edward N. And Della L. Thome Memorial Foundation, and was one of only eight Awards in Alzheimer's Disease Drug Discovery Research to be given in the U.S. in 2010.

25 Jan 2011

Human model of rare genetic disease reveals new clues to aging process

Scientists from A*STAR's Institute of Medical Biology (IMB) in Singapore and the University of Hong Kong's Department of Medicine have produced the world's first human cell model of progeria, a disease resulting in severe premature ageing in one in four to eight million children worldwide. This model has allowed them to make new discoveries concerning the mechanism by which progeria works.

25 Jan 2011

Researchers design engineered organ study the use of nanoparticles in breast cancer detection

Purdue University researchers have reproduced portions of the female breast in a tiny slide-sized model dubbed "breast on-a-chip" that will be used to test nanomedical approaches for the detection and treatment of breast cancer.

25 Jan 2011

Simple means of improving binding affinity of synbodies

Antibodies are watchdogs of human health, continuously prowling the body and registering minute changes associated with infection or disease with astonishing acuity. They also serve as biochemical memory banks, faithfully recording information about pathogens they encounter and efficiently storing this data for later use.

25 Jan 2011

Research finds faster developmental rate incurs lethal physiological costs for individuals

Fast development is often perceived as an advantage, as it enables better harmony with one's environment and readiness to cope with the challenges that it poses. However, research conducted at the University of Haifa, Israel, and University of California, Santa Cruz, and published in the scientific journal PLoS ONE, found that the acceleration of developmental rate incurs potentially lethal physiological costs for the developing individual.

25 Jan 2011

New investigative tool may explore intracellular processes with unprecedented clarity

Nongjian Tao and his colleagues at the Biodesign Institute at Arizona State University have pioneered a new technique capable of peering into single cells and even intracellular processes with unprecedented clarity.

25 Jan 2011

New research reveals dynamics behind signal transmission in brain

Surprising rate at which neuronal networks in the cerebral cortex delete sensory information. The dynamics behind signal transmission in the brain are extremely chaotic. This conclusion has been reached by scientists from the Max Planck Institute for Dynamics and Self-Organization at the University of Göttingen and the Bernstein Center for Computational Neuroscience Göttingen.

24 Jan 2011

Bax factor that promotes cell death is also involved in regulating mitochondria behavior

New research led by UC Davis scientists provides insight into why some body organs are more susceptible to cell death than others and could eventually lead to advances in treating or preventing heart attack or stroke.

24 Jan 2011

University of California study may shed light on human ability to adapt hypoxia

In an important study that may shed light on human ability to adapt to hypoxia, or inadequate levels of oxygen, researchers at the University of California, San Diego School of Medicine have proven that the genome of flies exposed to long-term hypoxia are changed to permanently affect gene expression.

24 Jan 2011

New study shows biomarker test can aid in early, precise diagnosis of melanoma

A new study shows that a test of biomarkers for DNA methylation is technically feasible and could aid in earlier, more precise diagnosis of melanoma.

24 Jan 2011

Women pregnant after egg donation are high-risk patients

Women who have become pregnant after egg donation should be categorized as high-risk patients. Why that is the case, and which consequences egg donation may have for women is the subject of a review article by Ulrich Pecks and co-authors from the University Hospital Aachen in the current issue of Deutsches Ärzteblatt International.

24 Jan 2011

Rogue gene blocked by right drugs could stop cancer

Scientists at the University of East Anglia (UEA) have discovered a rogue gene which - if blocked by the right drugs - could stop cancer in its tracks.

24 Jan 2011

Breakthrough in understanding mechanisms behind hereditary alpha-1-antitrypsin deficiency

Researchers from the Royal College of Surgeons in Ireland (RCSI) and Beaumont Hospital have made a breakthrough in understanding the mechanisms behind the most severe form of hereditary emphysema and how protein treatments can improve the condition. The findings of this study may also lead to new treatments for patients with smoker's emphysema.

24 Jan 2011