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Thymosin beta 4 improves neurological functional outcome after embolic stroke: Researchers

RegeneRx Biopharmaceuticals, Inc. today announced a research team from the Henry Ford Hospital in Detroit, MI, reported that Thymosin beta 4, administered to rats after embolic stroke, improved neurological functional outcome compared to control animals.

20 Jul 2010

Global study on working memory and influence of advertising on behaviour launched

Is your glass half full or half empty? Are you eternally optimistic or permanently pessimistic? What could this mean for your mental health? The British Science Association today launches a global study testing your working memory in relation to your mental health and then investigating the influence of advertising on your behaviour.

20 Jul 2010

Abbott presents 48-week PROGRESS study results at 28th International AIDS Conference

Abbott today presented 48-week findings comparing an HIV regimen of its protease inhibitor (PI), Kaletra® (lopinavir/ritonavir), and Merck's integrase inhibitor, Isentress® (raltegravir), to a traditional HIV regimen of Kaletra and the nucleotide/nucleoside reverse transcriptase inhibitors (NRTIs) in Truvada® (tenofovir and emtricitabine) in antiretroviral-naive adult patients. Efficacy data were collected over the first 48 weeks of the 96-week PROGRESS (PROtease/InteGRasE Simplification Study) study.

20 Jul 2010

Researchers discover new gene regulation, DNA behavior of breast cancer cells

Cancer researchers have discovered a previously unknown type of gene regulation and DNA behavior in breast cancer cells that may lead to better insight about environmental exposure to estrogen-like compounds. A new study, published in the journal Genome Research by researchers at The Ohio State University Comprehensive Cancer Center-Arthur G. James Cancer Hospital and Richard J. Solove Research Institute (OSUCCC-James), provides the first evidence that cells can regulate many genes at once by looping their DNA, contributing to cancer when it goes awry. In this study, the gene regulation was discovered in breast cancer cells as a response to the hormone estrogen and resulted in the silencing of 14 genes at one time.

20 Jul 2010

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Kidney disease is a growing public health problem, with approximately half a million individuals in the United States requiring dialysis treatments to replace the function of their failed kidneys. The problem is particularly acute among African-Americans, whose rates of kidney disease are four times higher than those of European Americans.

20 Jul 2010

Researchers identify a mechanism that explains different phases of CML progression

Researchers at Duke University Medical Center have identified a mechanism that could explain how patients move into the worst phase of chronic myelogenous leukemia.

20 Jul 2010

Bionas launches new Bionas adcon reader for impedance-based, cellular analysis

Bionas GmbH announces the launch of its new Bionas® adcon reader for impedance-based, cellular analysis. The Bionas adcon reader technology is based on real-time monitoring of cellular impedance, thus giving real-time data about cell adhesion, membrane integrity, cellular morphology and cell proliferation for applications in toxicology, oncology, receptor signaling as well as the quality management of cells.

19 Jul 2010

Researchers develop new method for producing image of individual DNA molecules' genetic make-up

A completely new method for producing an image of individual DNA molecules' genetic make-up has been developed by researchers in Sweden and Denmark. The results are published in the latest issue of the journal Proceedings of the National Academy of Sciences of the USA (PNAS).

19 Jul 2010

Study evaluates immunization benefits of dissolving microneedles

A new vaccine-delivery patch based on hundreds of microscopic needles that dissolve into the skin could allow persons without medical training to painlessly administer vaccines - while providing improved immunization against diseases such as influenza.

19 Jul 2010

Over-expression of CIB1 protein triggers biochemical processes that lead to cardiac hypertrophy: Study

Scientists have identified a key molecular regulator of cardiac hypertrophy (enlargement of the heart) that may provide a therapeutic target for a major risk factor of heart failure and early death.

19 Jul 2010

Tet 1 protein helps stem cells renew themselves and stay pluripotent: Researchers

Take a skin cell from a patient with Type 1 diabetes. Strip out everything that made it a skin cell, then reprogram it to grow into a colony of pancreatic beta cells. Implant these into your patient and voilà! She's producing her own insulin like a pro.

19 Jul 2010

Olig1 and Olig2 genes are associated with Down syndrome, scientists identify

Down syndrome is a well known cause of mental retardation and other medical problems, including early onset of Alzheimer disease. It has long been known that Down syndrome is associated with an individual having an additional copy of chromosome 21. Research findings reported in the July 18 advanced online publication of Nature Neuroscience have narrowed down the critical genetic elements responsible for some aspects of Down syndrome.

19 Jul 2010

New mechanism that drives development of B-lymphocytes in bone marrow discovered

Scientists from the Department of Molecular Immunology, Institute of Biology III, Faculty of Biology and the Centre for Biological Signalling Studies, BIOSS have discovered a new mechanism that drives the development of B-lymphocytes in our bone marrow. B-lymphocytes are an important part of our immune system. Upon their activation they produce the antibodies protecting us from infections.

17 Jul 2010

Species with larger brains live longer

"In the past, it was thought that one of the selective advantages of having a large brain is that it facilitates the development of new behaviour to respond to the ecological challenges that the individual has not experienced before, such as a sudden reduction in food or the appearance of a new predator ", C-sar Gonz-lez-Lagos, main author of the study and researcher at the Centre of Ecological Research and Forestry Applications (CREAF) associated with the Autonomous University of Barcelona, highlights to SINC.

17 Jul 2010

New tactics for repelling, controlling disease-carrying insects

In the battle between insect predators and their prey, chemical signals called kairomones serve as an early-warning system. Pervasively emitted by the predators, the compounds are detected by their prey, and can even trigger adaptations, such a change in body size or armor, that help protect the prey. But as widespread as kairomones are in the insect world, their chemical identity has remained largely unknown. New research by Rockefeller University's Joel E. Cohen and colleagues at the University of Haifa in Israel has identified two compounds emitted by mosquito predators that make the mosquitoes less inclined to lay eggs in pools of water.

17 Jul 2010

GABA disrupts working memory in neurofibromatosis type 1 patients

Imagine if your brain lost its working memory - the ability to hold and manipulate information in your mind's eye. That's the plight faced by millions of people with neurofibromatosis type 1, or NF1. The genetic condition affects one in 3,500 people and is the most common cause of learning disabilities.Now a UCLA research team has uncovered new clues about how NF1 disrupts working memory. Published in the July 12 online edition of Proceedings of the National Academy of Sciences, the findings suggest a potential drug target for correcting NF1-related learning disabilities.

17 Jul 2010

Cetuximab recommended for colorectal cancer tumors without mutation in KRAS gene

In a report published in the July 2010 issue of the American Society for Clinical Oncology Post, new recommendations on the use of the drug cetuximab have been issued after officials halted enrollment in a phase III clinical trial in patients with spread of colon cancer into regional lymph nodes whose tumors had been surgically removed.

17 Jul 2010

CCTP focuses on identifying, testing drugs for cancer stem cell treatment

Cancer and stem cell biology researchers at the University of Colorado are launching the nation's first program focused on identifying and testing drugs that target and destroy cells thought to be at the root of cancer-cancer stem cells (CSCs).The Cancer Stem Cell-Directed Clinical Trials Program (CCTP) is a collaboration between the University of Colorado Cancer Center and the Charles C. Gates Center for Regenerative Medicine and Stem Cell Biology, both located at the University of Colorado School of Medicine.

17 Jul 2010

AMPK may regulate epigenetic mechanism: Research

AMP-activated protein kinase, or AMPK, is a master regulator protein of metabolism that is conserved from yeast to humans. When a cell is low on fuel, AMPK shuts down processes that use energy and turns on processes that produce energy.Biologists have been studying how AMPK works for several decades and know that once it is activated, AMPK turns on a large number of genes by passing the "make more energy" message through numerous signaling cascades in the cell. What was not known, until now, was that AMPK also works via an epigenetic mechanism to slow down or stop cell growth.

17 Jul 2010

InformedDNA named finalist for Best Practices in Health Care Consumer Empowerment and Protection Awards

Informed Medical Decisions, Inc. (InformedDNA) has been selected as one of 30 finalists for the Best Practices in Health Care Consumer Empowerment and Protection Awards. URAC, the nation's leading accreditation organization, will honor the finalists during their 11th Annual Quality Summit, October 5-7, 2010 in Chicago, IL.

17 Jul 2010

Medical Science News

Thymosin beta 4 improves neurological functional outcome after embolic stroke: Researchers

Global study on working memory and influence of advertising on behaviour launched

Abbott presents 48-week PROGRESS study results at 28th International AIDS Conference

Researchers discover new gene regulation, DNA behavior of breast cancer cells

Researchers discover genetic explanation for non-diabetic kidney disease in African-Americans

Researchers identify a mechanism that explains different phases of CML progression

Bionas launches new Bionas adcon reader for impedance-based, cellular analysis

Researchers develop new method for producing image of individual DNA molecules' genetic make-up

Study evaluates immunization benefits of dissolving microneedles

Over-expression of CIB1 protein triggers biochemical processes that lead to cardiac hypertrophy: Study

Tet 1 protein helps stem cells renew themselves and stay pluripotent: Researchers

Olig1 and Olig2 genes are associated with Down syndrome, scientists identify

New mechanism that drives development of B-lymphocytes in bone marrow discovered

Species with larger brains live longer

New tactics for repelling, controlling disease-carrying insects

GABA disrupts working memory in neurofibromatosis type 1 patients

Cetuximab recommended for colorectal cancer tumors without mutation in KRAS gene

CCTP focuses on identifying, testing drugs for cancer stem cell treatment

AMPK may regulate epigenetic mechanism: Research

InformedDNA named finalist for Best Practices in Health Care Consumer Empowerment and Protection Awards

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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