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Takeda Cambridge, Evotec enter collaboration to identify novel modulators against GPCR

Evotec AG today announced that it has entered into a collaboration with Takeda Cambridge Limited, to identify small molecule modulators against GPCR and Protease targets involved in various CNS and Metabolic diseases.

20 Jan 2011

University of Minnesota grants Cellectis rights related to TAL effector-mediated DNA recognition and cleavage

Cellectis, the French genome engineering specialist, has announced today that it has signed an exclusive license agreement with the University of Minnesota that grants Cellectis the worldwide right to use inventions related to TAL effector-mediated DNA recognition and cleavage. This revolutionary approach for the targeted modification of genomes was developed by the University of Minnesota and Iowa State University.

20 Jan 2011

Writing by hand strengthens learning process, while keyboard typing impairs

When writing by hand, our brain receives feedback from our motor actions, together with the sensation of touching a pencil and paper. These kinds of feedback is significantly different from those we receive when touching and typing on a keyboard.

20 Jan 2011

Endothelial cells may play a role in controlling cancer behavior: New study

MIT scientists have discovered that cells lining the blood vessels secrete molecules that suppress tumor growth and keep cancer cells from invading other tissues, a finding that could lead to a new way to treat cancer.

20 Jan 2011

Scarab Genomics, WIST enter research agreement to produce isoprene from paper, pulp mill waste streams

Scarab Genomics, a leader in the development of production E. coli strains based on reduced genome technology and the Wisconsin Institute for Sustainable Technology at the University of Wisconsin-Stevens Point have entered into a research agreement to produce isoprene from paper and pulp mill waste streams.

20 Jan 2011

Findings could speed use of RNA nanotechnology for treating disease

Scientists are reporting an advance in overcoming a major barrier to the use of the genetic material RNA in nanotechnology - the field that involves building machines thousands of times smaller than the width of a human hair and now is dominated by its cousin, DNA. Their findings, which could speed the use of RNA nanotechnology for treating disease, appear in the monthly journal ACS Nano.

20 Jan 2011

Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

In a collaborative project involving scientists from three continents, researchers have identified a gene that is mutated in one in three patients with the most common form of renal cancer.

20 Jan 2011

Oral contraceptives do not cause weight gain, says new study

According to research conducted at the Oregon National Primate Research Center at Oregon Health & Science University, the commonly held belief that oral contraceptives cause weight gain appears to be false. The results of the study are published online and will appear in next month's edition of the journal Human Reproduction.

20 Jan 2011

Small molecules may inhibit entry of Ebola into human cells

Ebola, a virus that causes deadly hemorrhagic fever in humans, has no known cure or vaccine. But a new study by University of Illinois at Chicago scientists has uncovered a family of small molecules which appear to bind to the virus's outer protein coat and may inhibit its entry into human cells.

20 Jan 2011

Researchers discover how Ras oncogene chooses a signaling pathway

The National Cancer Institute estimates that more than 43,000 Americans were diagnosed with pancreatic cancer last year and more than 36,000 died from the disease. Despite advances in genetic science showing that the Ras oncogene is mutated in virtually all pancreatic cancers, scientists have been frustrated by the complexity of the signaling pathways in humans, which make it difficult to pinpoint potential therapeutic targets.

20 Jan 2011

Scientists determine protein structure that delivers genetic material of HIV to human cells

A team of scientists at The Scripps Research Institute and the University of Virginia has determined the structure of the protein package that delivers the genetic material of the human immunodeficiency virus to human cells.

19 Jan 2011

Malaria parasite caught in action on film for the first time

Australian researchers have managed to take pictures of microscopic malaria parasite as it invades a human red blood cell. This will provide a deeper understanding of the parasite’s behaviour and may help fight it. Up to 10% of the world’s population contract malaria every year and a million people, mostly pregnant women and children, die as a result of the parasite transmitted by infected mosquitoes.

19 Jan 2011

Salk Institute uncovers presenilin's productive side

Mutant presenilin is infamous for its role in the most aggressive form of Alzheimer's disease-early-onset familial Alzheimer's-which can strike people as early as their 30s. In their latest study, researchers at the Salk Institute uncovered presenilin's productive side: It helps embryonic motor neurons navigate the maze of chemical cues that pull, push and hem them in on their way to their proper targets.

19 Jan 2011

Pisgah to scale-up patent-pending form of hydrocodone

As Pisgah Laboratories, Inc. continues development of its lead abuse deterrent opioid product, it will soon begin scale-up of its patent-pending form of hydrocodone. Pisgah has developed a specialized salt form of hydrocodone which imparts abuse deterrent properties to a dosage product. Pisgah will manufacture its hydrocodone salt for clinical trials in their FDA / DEA registered facility.

19 Jan 2011

National Jewish Health issued method patent for desensitizing B cells

National Jewish Health has been issued a US patent claiming a method to desensitize B cells by inactivating antigen receptors on their surfaces. The method, discovered by John Cambier, PhD, Chairman of the Integrated Department of Immunology at National Jewish Health, holds promise for treatment of B-cell mediated diseases, such as lymphoma and leukemia, rheumatoid arthritis, lupus and rejection of organ transplants.

19 Jan 2011

Case Western Reserve, Athersys enter partnership for scientific study on spinal cord injury

Case Western Reserve University School of Medicine and Athersys, Inc. announced a joint scientific study on spinal cord injury will be published today in the January issue of The Journal of Neuroscience.

19 Jan 2011

Patients with varied patchwork of genetic faults in tumours have worse outcomes

Cancer Research UK scientists have discovered that cervical cancer patients who have a mixture of different genetic faults in their tumour at the start of treatment may be more likely to relapse, according to a study published in the British Journal of Cancer today.

19 Jan 2011

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

A complex sugar may someday become one of the most effective weapons to stop the spread of cholera, a disease that has claimed thousands of lives in Haiti since the devastating earthquake last year.

19 Jan 2011

Study demonstrates role of alpha-synuclein cell-to-cell transfer in Parkinson's disease pathogenesis

The misfolding of abnormal proteins in brain cells is a key element in Parkinson's disease development. A recent study suggests that the sick proteins slowly move between cells, eventually triggering the destruction of the new host cell. The discovery could potentially lead to new therapeutic strategies for neurodegenerative diseases aimed at blocking the spread of protein misfolding throughout the brain.

19 Jan 2011

UNC scientists discover how chaperone enzyme plays a key role in cells' ability to tolerate DNA damage

UNC scientists who study how cells repair damage from environmental factors like sunlight and cigarette smoke have discovered how a "chaperone" enzyme plays a key role in cells' ability to tolerate the DNA damage that leads to cancer and other diseases.

19 Jan 2011

Medical Science News

Takeda Cambridge, Evotec enter collaboration to identify novel modulators against GPCR

University of Minnesota grants Cellectis rights related to TAL effector-mediated DNA recognition and cleavage

Writing by hand strengthens learning process, while keyboard typing impairs

Endothelial cells may play a role in controlling cancer behavior: New study

Scarab Genomics, WIST enter research agreement to produce isoprene from paper, pulp mill waste streams

Findings could speed use of RNA nanotechnology for treating disease

Researchers identify PBRM1 gene mutation in one in three patients with common form of renal cancer

Oral contraceptives do not cause weight gain, says new study

Small molecules may inhibit entry of Ebola into human cells

Researchers discover how Ras oncogene chooses a signaling pathway

Scientists determine protein structure that delivers genetic material of HIV to human cells

Malaria parasite caught in action on film for the first time

Salk Institute uncovers presenilin's productive side

Pisgah to scale-up patent-pending form of hydrocodone

National Jewish Health issued method patent for desensitizing B cells

Case Western Reserve, Athersys enter partnership for scientific study on spinal cord injury

Patients with varied patchwork of genetic faults in tumours have worse outcomes

Dextran-coated onto iron oxide nanoparticles can detect cholera toxin: Study

Study demonstrates role of alpha-synuclein cell-to-cell transfer in Parkinson's disease pathogenesis

UNC scientists discover how chaperone enzyme plays a key role in cells' ability to tolerate DNA damage

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