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BioTime acquires ES Cell International

BioTime, Inc., a biotechnology company that develops and markets products in the field of human stem cells and regenerative medicine, today announced that it has completed its acquisition of the Singapore company ES Cell International Pte Ltd.

3 May 2010

Alnylam Pharmaceuticals announces EPO intent to grant notification for patent series covering RNAi therapeutics

Alnylam Pharmaceuticals, Inc., a leading RNAi therapeutics company, announced today that the European Patent Office (EPO) has issued a notification of an intent to grant for the "Manoharan II" patent series (EP Application No 04 718 537), titled "Therapeutic Compositions." The new patent includes 16 claims covering compositions and methods, including pharmaceutical compositions, for chemically modified siRNAs containing phosphorothioate and 2′-O-alkyl modifications without any siRNA length restrictions.

3 May 2010

Progress in development of gene therapies for inherited blindness caused by rod degeneration

Veterinary vision scientists at the University of Pennsylvania have safely and successfully used a viral vector in targeting a class of photoreceptors of the retina called rods, a critical first step in developing gene therapies for inherited blindness caused by rod degeneration.

3 May 2010

Family Tree DNA announces launch of Family Finder DNA test

Family Tree DNA, the first and largest genealogical DNA testing company, today announced the launch of the Family Finder DNA test for connecting family members across all ancestral lines. The test utilizes Affymetrix' recently launched Axiom genotyping technology and the GeneTitan® System to confidently match a wide range of family relationships within five generations.

3 May 2010

SARcode presents positive results from Phase 2 study of SAR 1118 ophthalmic solution at Dry Eye Summit

SARcode Corporation, a privately-held biotechnology company focused on developing a novel class of lymphocyte function-associated antigen-1 (LFA-1) antagonists, today announced results of a 230 patient Phase 2 proof-of-concept study evaluating topical SAR 1118 ophthalmic solution in the treatment of aqueous deficient dry eye (keratoconjunctivitis sicca).

3 May 2010

Stimatix reports interim results from artificial sphincter trial for restoring bowel control in people with stoma

Stimatix GI, located in the Misgav Venture Accelerator, has reported encouraging interim results in its animal trials of the AOS-C1000 artificial sphincter, designed to provide stoma patients with a new means of bowel control.

3 May 2010

Scientist to receive 2010 March of Dimes Prize in Developmental Biology

The scientist who reprogrammed adult cells into embryonic-like stem cells has been chosen to receive the 2010 March of Dimes Prize in Developmental Biology.

3 May 2010

Protein test to determine response of lung cancer patients to erlotinib

Testing for the presence of specific cancer protein 'fingerprints' in the blood of lung cancer patients may be a useful means of identifying a subgroup whose tumors are more likely to shrink when treated with the drug erlotinib, especially when other testing methods are unavailable, according to new data presented at the 2nd European Lung Cancer Conference in Geneva, Switzerland.

3 May 2010

Scripps Research Institute awarded grant to design assays for exploring potential target for obesity, Type 2 diabetes

The Scripps Research Institute has been awarded a $1.3 million grant by the National Institutes of Health (NIH) to develop a series of tests at its Florida campus to help explore the potential of a protein that has emerged as a highly attractive target for the treatment of obesity and Type 2 diabetes.

3 May 2010

Roche's xCELLigence System helps study cell viability, cell death while testing cytotoxic compounds

Monitoring of cell viability and toxicity are critical to many areas of biological and biomedical research. This is true for understanding the molecular and biochemical pathways regulating cell viability, for developing therapeutic agents which modulate cell viability and for identifying potential cytotoxic side effects of potential therapeutic agents.

3 May 2010

Leptin hormone controls immune’s response to sepsis: Study

The hormone leptin, typically associated with body weight regulation, works within the central nervous system (CNS) to aid the immune system's defense against sepsis, researchers say.

3 May 2010

Researchers explore use of nanomedicine techniques for treatment of diseases in children

"Children are not small adults"—pediatricians say that's what makes their specialty different from the practice of medicine in adults. For similar reasons, researchers exploring the medical uses of nanotechnology believe that the use of molecular-level nanomedicine techniques in children will also require its own specialty.

3 May 2010

New research suggests tumor-secreted exosomes inhibit immune response, enhance tumor metastasis

Current research suggests that tumor-secreted exosomes inhibit the immune response, enhancing tumor metastasis. The related report by Liu et al, "Contribution of MyD88 to the tumor exosome-mediated induction of myeloid derived suppressor cells," appears in the May 2010 issue of The American Journal of Pathology.

3 May 2010

Scientists discover two body clock genes that may help find treatments for seasonal affective disorder

Scientists have discovered two "body clock" genes that reveal how seasonal changes in hormones are controlled and could ultimately help find treatments for seasonal affective disorder.

3 May 2010

Scientists discover three genes linked to development of Paget's disease

Scientists have discovered three genes linked to the development of Paget's disease, a painful bone condition that affects up to one million people in the UK.

3 May 2010

Researchers discover a new driving force behind cancer growth

Researchers from the University of Leeds, UK, the Charit- University Medical School and the Max Delbr-ck Centre for Molecular Medicine (MDC) in Berlin, Germany, have discovered a new driving force behind cancer growth.

3 May 2010

Mutations in several genes associated with developmental brain disorder: Study

Although there is no known cause of autism, studies have shown that mutations in several genes are associated with the developmental brain disorder. New research has uncovered two additional genes that may be involved with autism.

3 May 2010

McGill scientist discovers how one particular gene regulates epithelial cells

New research led by McGill Biochemist Dr. William Muller helps explain why breast-milk cells lose their structure, causing them to clump up in strange ways (photos available) and sometimes become cancer tumors. With the support of Chen Ling and Dongmei Zuo at McGill's Goodman Cancer Centre, Muller has discovered how one particular gene regulates epithelial cells - cells that normally form in sheets and are polarized to enable the transport of molecules in a single direction.

30 Apr 2010

Research shows microRNA can silence genes that protect genome from cancer-causing mutations

New research shows for the first time that molecules called microRNA can silence genes that protect the genome from cancer-causing mutations.

30 Apr 2010

Pieris AG announces preclinical data for proprietary PRS-110 Anticalin compound

Pieris AG announced today preclinical data for its proprietary PRS-110 Anticalin compound, which targets the c-Met receptor, demonstrating a dose-dependant reduction of tumor growth in a xenograft mouse model.

30 Apr 2010

Medical Science News

BioTime acquires ES Cell International

Alnylam Pharmaceuticals announces EPO intent to grant notification for patent series covering RNAi therapeutics

Progress in development of gene therapies for inherited blindness caused by rod degeneration

Family Tree DNA announces launch of Family Finder DNA test

SARcode presents positive results from Phase 2 study of SAR 1118 ophthalmic solution at Dry Eye Summit

Stimatix reports interim results from artificial sphincter trial for restoring bowel control in people with stoma

Scientist to receive 2010 March of Dimes Prize in Developmental Biology

Protein test to determine response of lung cancer patients to erlotinib

Scripps Research Institute awarded grant to design assays for exploring potential target for obesity, Type 2 diabetes

Roche's xCELLigence System helps study cell viability, cell death while testing cytotoxic compounds

Leptin hormone controls immune’s response to sepsis: Study

Researchers explore use of nanomedicine techniques for treatment of diseases in children

New research suggests tumor-secreted exosomes inhibit immune response, enhance tumor metastasis

Scientists discover two body clock genes that may help find treatments for seasonal affective disorder

Scientists discover three genes linked to development of Paget's disease

Researchers discover a new driving force behind cancer growth

Mutations in several genes associated with developmental brain disorder: Study

McGill scientist discovers how one particular gene regulates epithelial cells

Research shows microRNA can silence genes that protect genome from cancer-causing mutations

Pieris AG announces preclinical data for proprietary PRS-110 Anticalin compound

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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