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Genetic variations in Y chromosome affect men's risk of coronary heart disease: Scientists

Scientists in the UK have shown that genetic variations in the Y chromosome affect a male's risk of coronary heart disease. It is well known that males have a higher incidence of coronary heart disease than females due, in part, to the Y chromosome they inherit from their fathers. To investigate the role of the Y chromosome further, a team from the University of Leicester carried out research to determine whether genetic variations in the Y-chromosome affect risk for males.

30 Aug 2010

Low doses of n-3 fatty acids do not reduce overall rate of major cardiovascular events

Results from the Alpha Omega Trial, a multicentre, placebo-controlled trial in men and women following myocardial infarction (MI), suggest that low doses of n-3 fatty acids given in the form of enriched margarines do not reduce the overall rate of major cardiovascular events.

30 Aug 2010

Latest achievements in brain research and treatment for mental disorders

Mental disorders, such as depression, anxiety disorders, addiction and schizophrenia are the core challenge of most health care systems around the world. In the EU alone, each year 27% of the total adult population - this corresponds to 83 Million citizens - suffer from mental disorders. Depression alone affects almost 20 million ranking in the EU as the most disabling disorder of all diseases.

30 Aug 2010

Study finds bone marrow stem cell therapy improves efficacy in chronic heart failure

Bone marrow stem cell therapy improves ventricular performance, quality of life and survival in patients with chronic heart failure, according to results from the STAR-heart study.

30 Aug 2010

Researchers examine functions of neuronal diversity

Much like snowflakes, no two neurons are exactly alike. But it's not the size or shape that sets one neuron apart from another, it's the way it responds to incoming stimuli. Carnegie Mellon University researchers have discovered that this diversity is critical to overall brain function and essential in how neurons process complex stimuli and code information.

30 Aug 2010

Cell-to-cell signaling pathway that designates future location of ear's sensory organs tracked

Researchers have tracked a cell-to-cell signaling pathway that designates the future location of the ear's sensory organs in embryonic mice. The scientists succeeded in activating this signal more widely across the embryonic tissue that becomes the inner ear. Patches of sensory structures began growing in spots where they don't normally appear.

30 Aug 2010

Scientists develop microarray technology to create blood transcriptional signatures for infectious diseases

It may soon be possible to identify patients who will develop tuberculosis, as scientists have identified changes in the blood specific to the disease. These findings are from an international study published in the August 19 issue of Nature and conducted by doctors and researchers at Nationwide Children's Hospital using blood profiling techniques to understand infections.

30 Aug 2010

Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists at Jefferson Medical College have received a four-year, $3 million National Institutes of Health grant funded by the National Heart, Lung and Blood Institute to study variations of platelet function, specifically, the genetics of platelet gene expression. The study aims to find data that can be translated into novel therapeutic strategies and develop better predictors of cardiovascular disease.

30 Aug 2010

Scientists develop new combined treatment method for skin cancer prevention

Scientists at The University of Texas Health Science Center San Antonio are on to something that should bring joy to sunbathers everywhere. Studies show that certain plant substances, administered in combinations, have the ability to suppress skin cancer development in susceptible mice.

30 Aug 2010

Scientists identify genetic basis to determine severity of allergic asthma in experimental models

Scientists have identified a genetic basis for determining the severity of allergic asthma in experimental models of the disease.The study may help in the search for future therapeutic strategies to fight a growing medical problem that currently lacks effective treatments, researchers from Cincinnati Children's Hospital Medical Center report in the Aug. 29 Nature Immunology.

30 Aug 2010

New high throughput sequencing technology to identify genetic defects in rare diseases

The majority of rare diseases are hereditary. But despite significant progress in genome research, in most cases their exact cause remains unclear. The discovery of the underlying genetic defect is, however, a prerequisite for their definitive diagnosis and the development of innovative approaches to their treatment. Scientists at the Max Planck Institute for Molecular Genetics and the Institute of Medical Genetics at the Charit- Universit-tsmedizin - Berlin have succeeded in using a new process with which all of the genes in the human genome can be analysed simultaneously.

30 Aug 2010

Edwards uses his hands after double hand transplant at Jewish Hospital Hand Care Center

Dr. Richard "Rich" Edwards got a look at his new hands for the first time today when all the bandages were removed so doctors could evaluate how the hands are doing. A team of surgeons from Kleinert Kutz and Associates and the University of Louisville performed a double hand transplant on the Oklahoma resident during a 17 ½ hour surgical procedure beginning August 24 at the Jewish Hospital Hand Care Center.

30 Aug 2010

Researchers recommend action to reverse federal court decision on embryonic stem cell research ban

Against a backdrop of some of the world's most sophisticated biological research labs, Rep. Steve Israel (D-Huntington) this morning issued a challenge to his colleagues in Congress immediately upon their return from summer recess, he urged, they should pass legislation that would reverse a recent Federal court decision that has brought embryonic stem cell research in the U.S. to a screeching halt.

30 Aug 2010

Study reveals impact of genetic make-up on response to oral antiplatelet treatment ticagrelor

A new genetic substudy of PLATO showed that the effects on a combined primary endpoint of cardiovascular death, myocardial infarction, or stroke seen in Acute Coronary Syndromes patients who received the investigational oral antiplatelet treatment, ticagrelor (BRILINTA), were maintained, whether or not they had the genetic variability that has been previously shown to affect a patient's response to clopidogrel.

30 Aug 2010

GWAS finds new genetic link between Parkinson's disease and inflammation

A hunt throughout the human genome for variants associated with common, late-onset Parkinson's disease has revealed a new genetic link that implicates the immune system and offers new targets for drug development.

30 Aug 2010

Study finds BMI, thrombogenic factor increases cardiovascular risk

Although having a high body mass index (BMI) is a known risk factor for cardiovascular disease, researchers are only beginning to understand how BMI affects the physiological processes involved in the development of the disease. Now, a study of a subset of women in the Kronos Early Estrogen Prevention Study (KEEPS), suggests that as BMI increases, so do platelet reactivity and thrombogenic microvesicles and activated protein C in the blood-all of which contribute to the formation of atherothrombosis and associated cardiovascular events.

30 Aug 2010

David Mosser to discuss primary duty of macrophages at American Physiological Society conference

The term "macrophage" conjures images of a hungry white blood cell gobbling invading bacteria. However, macrophages do much more than that. Not only do they act as antimicrobial warriors, they also play critical roles in immune regulation and wound-healing. They can respond to a variety of cellular signals and change their physiology in response to local cues.

27 Aug 2010

Research: Impact of seafood components on human health

Seafood has an enormous potential to promote health. At the same time the opportunities for innovation and value creation are huge. Knowledge and documentation are the keys to success.

27 Aug 2010

Mixed pathologies in brains of elderly account for memory loss and confusion

Most recent studies show that elderly people over the age of 80 often have mixed pathologies in their brains that account for their memory loss and confusion. Very few senior citizens have "pure Alzheimer disease"; therefore, this terminology should be used with caution. It now appears that vascular problems such as high blood pressure and diabetes can shrink the parts of the brain that control memory and can significantly affect at what age elderly people become demented.

27 Aug 2010

Athera Biotechnologies, Electra-Box Diagnostica sign distribution agreement for 'CVDefine' kit

Athera Biotechnologies and Electra-Box Diagnostica, announced today that they have signed an agreement for distribution of "CVDefine" kit. CVDefine measures a new biomarker in blood, a specific anti-body, that has been linked to increased risk for cardiovascular disease. Athera Biotechnologies is part of the Karolinska Development portfolio.

27 Aug 2010

Medical Science News

Genetic variations in Y chromosome affect men's risk of coronary heart disease: Scientists

Low doses of n-3 fatty acids do not reduce overall rate of major cardiovascular events

Latest achievements in brain research and treatment for mental disorders

Study finds bone marrow stem cell therapy improves efficacy in chronic heart failure

Researchers examine functions of neuronal diversity

Cell-to-cell signaling pathway that designates future location of ear's sensory organs tracked

Scientists develop microarray technology to create blood transcriptional signatures for infectious diseases

Jefferson scientists receive grant to study genetics of platelet gene expression

Scientists develop new combined treatment method for skin cancer prevention

Scientists identify genetic basis to determine severity of allergic asthma in experimental models

New high throughput sequencing technology to identify genetic defects in rare diseases

Edwards uses his hands after double hand transplant at Jewish Hospital Hand Care Center

Researchers recommend action to reverse federal court decision on embryonic stem cell research ban

Study reveals impact of genetic make-up on response to oral antiplatelet treatment ticagrelor

GWAS finds new genetic link between Parkinson's disease and inflammation

Study finds BMI, thrombogenic factor increases cardiovascular risk

David Mosser to discuss primary duty of macrophages at American Physiological Society conference

Research: Impact of seafood components on human health

Mixed pathologies in brains of elderly account for memory loss and confusion

Athera Biotechnologies, Electra-Box Diagnostica sign distribution agreement for 'CVDefine' kit

The evolution of OCT for retinal imaging and disease intervention

Supercharging Next-Gen Antibody Discovery with AI and High-Throughput Experimentation

Prof. Dr. Kristina Kusche-Vihrog

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