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Obesity - Body's effort to protect organs from lipids' toxic effects

The collection of symptoms that is the metabolic syndrome-insulin resistance, high cholesterol, fatty liver, and a greater risk for diabetes, heart disease, and stroke-are all related to obesity, but, according to a review in the March 9th issue of the Cell Press publication Trends in Endocrinology and Metabolism, not in the way you probably think they are.

9 Mar 2010

New reservoir for hidden HIV-infected cells identified

University of Michigan scientists have identified a new reservoir for hidden HIV-infected cells that can serve as a factory for new infections. The findings, which appear online March 7 in Nature Medicine, indicate a new target for curing the disease so those infected with the virus may someday no longer rely on AIDS drugs for a lifetime.

9 Mar 2010

Three researchers to be honored with SBS Award for achievement in biomolecular sciences and lead discovery

The Society for Biomolecular Sciences will honor three researchers for their substantial contributions to the field of drug discovery. Each recipient will accept their award and speak at the SBS 16th Annual Conference & Exhibition in Phoenix, Arizona, April 11-15, 2010.

9 Mar 2010

Exposure to BPA during pregnancy causes permanent abnormalities in uterus of offspring

Researchers at Yale School of Medicine have discovered that exposure during pregnancy to Bisphenol A (BPA), a common component of plastics, causes permanent abnormalities in the uterus of offspring, including alteration in their DNA. The findings were reported in the March issue of Journal of the Federation of American Societies for Experimental Biology.

8 Mar 2010

Repeated anaesthesia in children linked to memory impairment

There is a link between repeated anaesthesia in children and memory impairment, though physical activity can help to form new cells that improve memory, reveals new research from the Sahlgrenska Academy at the University of Gothenburg, Sweden.

8 Mar 2010

Moderating treatment response in depression: Role of personality factors

A study published in the current issue of Psychotherapy and Psychosomatics addresses the role of personality factors in moderating treatment response in depression.

8 Mar 2010

NICE rejects azacitidine for treatment of MDS in patients ineligible for stem cell transplants

A drug for treating a group of conditions that affect the bone marrow is unlikely to be made available on the NHS in England and Wales after the body which provides independent advice on treatments said that it is unlikely to be cost-effective.

8 Mar 2010

Global Genes Project: World Rare Disease Day 2010, a tremendous success

The Global Genes Project, a worldwide rare disease awareness initiative, today announced the success from its World Rare Disease Day 2010 efforts and laid out plans for future rare disease awareness campaigns.

8 Mar 2010

Sigma Life Science extends portfolio of knockout rat models with the release of ADME/Tox applications

Sigma® Life Science, an innovative brand of Sigma-Aldrich®, today extended its portfolio of knockout rat models with the announcement of a new suite of models designed to facilitate more predictive absorption, distribution, metabolism, excretion and toxicity (ADME/Tox) studies.

8 Mar 2010

Improvements needed in communicating cancer recurrence risks and treatment decisions with patients

A new study has found that one in three early-stage breast cancer patients who received genomic testing when deciding about treatment options felt they did not fully understand their discussions with physicians about their test results and their risk of recurrence. About one in four experienced distress when receiving their test results.

8 Mar 2010

Men employed in occupations with potential exposure to sunlight have reduced risk of kidney cancer

According to a new study, men employed in occupations with potential exposure to high levels of sunlight have a reduced risk of kidney cancer compared with men who were less likely to be exposed to sunlight at work.

8 Mar 2010

Scientists identify EoE-associated region in human chromosome

Scientists have identified a region of a human chromosome that is associated with eosinophilic esophagitis (EoE), a recently recognized allergic disease. People with EoE frequently have difficulty eating or may be allergic to one or more foods. This study further suggests that a suspected so-called master allergy gene may play a role in the development of this rare but debilitating disorder.

8 Mar 2010

Scientists show Ritalin boosts cognitive abilities by enhancing brain plasticity

Doctors treat millions of children with Ritalin every year to improve their ability to focus on tasks, but scientists now report that Ritalin also directly enhances the speed of learning.

8 Mar 2010

Scientists identify the role of vitamin D in activation of T cells

Scientists at the University of Copenhagen have discovered that Vitamin D is crucial to activating our immune defenses and that without sufficient intake of the vitamin, the killer cells of the immune system - T cells - will not be able to react to and fight off serious infections in the body.

8 Mar 2010

Engineers built sensor array that can detect single molecules of hydrogen peroxide

MIT chemical engineers have built a sensor array that, for the first time, can detect single molecules of hydrogen peroxide emanating from a single living cell.

7 Mar 2010

Pediatrics researchers identify major gene location responsible for EoE

Pediatrics researchers have identified the first major gene location responsible for a severe, often painful type of food allergy called eosinophilic esophagitis (EoE). In this disease, which may cause weight loss, vomiting, heartburn and swallowing difficulties, a patient may be unable to eat a wide variety of foods.

7 Mar 2010

Antibacterial activity of clay minerals raises hope for natural approaches to antibacterial cures

Alternative approaches to medicine are stock-in-trade in the ASU laboratory of microbiologist Shelley Haydel.

6 Mar 2010

Researchers discuss possibility of using food to prevent individual's genes from expressing disease

Personal health recommendations and diets tailored to better prevent diseases may be in our future, just by focusing on genetics.

6 Mar 2010

Scientists succeed in mapping entire network of DNA-binding transcription factors

In a significant leap forward in the understanding of how specific types of tissue are determined to develop in mammals, an international team of scientists has succeeded in mapping the entire network of DNA-binding transcription factors and their interactions. This global network, indicating which factors can combine to determine cell fate, will be published in the March 5 issue of the journal Cell.

6 Mar 2010

Research group performs randomized study to evaluate efficacy of ICCBco in treatment of lung lesions

To evaluate efficacy of Calculus Bovis compound preparation (ICCBco) in the treatment of lung lesions in portal hypertensive rabbits with schistosomiasis as the experimental animal model, a research group in China performed a randomized, double-blind, controlled trial to observe pathological changes and pathological effect mechanism of expression of fibronectin and laminin in the lung tissue of portal hypertensive rabbits with schistosomiasis.

6 Mar 2010

Medical Science News

Obesity - Body's effort to protect organs from lipids' toxic effects

New reservoir for hidden HIV-infected cells identified

Three researchers to be honored with SBS Award for achievement in biomolecular sciences and lead discovery

Exposure to BPA during pregnancy causes permanent abnormalities in uterus of offspring

Repeated anaesthesia in children linked to memory impairment

Moderating treatment response in depression: Role of personality factors

NICE rejects azacitidine for treatment of MDS in patients ineligible for stem cell transplants

Global Genes Project: World Rare Disease Day 2010, a tremendous success

Sigma Life Science extends portfolio of knockout rat models with the release of ADME/Tox applications

Improvements needed in communicating cancer recurrence risks and treatment decisions with patients

Men employed in occupations with potential exposure to sunlight have reduced risk of kidney cancer

Scientists identify EoE-associated region in human chromosome

Scientists show Ritalin boosts cognitive abilities by enhancing brain plasticity

Scientists identify the role of vitamin D in activation of T cells

Engineers built sensor array that can detect single molecules of hydrogen peroxide

Pediatrics researchers identify major gene location responsible for EoE

Antibacterial activity of clay minerals raises hope for natural approaches to antibacterial cures

Researchers discuss possibility of using food to prevent individual's genes from expressing disease

Scientists succeed in mapping entire network of DNA-binding transcription factors

Research group performs randomized study to evaluate efficacy of ICCBco in treatment of lung lesions

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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