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Humacyte, Xcellerex collaborate to develop novel vascular graft for transplantation technologies

Humacyte, Inc. and Xcellerex, Inc. have entered into an initial strategic collaboration for Xcellerex to develop a novel manufacturing process that will enable the production of Humacyte’s lead regenerative medicine product using Xcellerex’s XDR single use bioreactor system in its FlexFactory®. Humacyte’s product is a large diameter vascular graft that is based on its innovative and proprietary platform technology for engineering human, extracellular matrix-based tissues that have properties that are similar to native tissues.

5 Mar 2010

Argos Therapeutics' AGS-004 immunotherapy for HIV demonstrates clinical and commercial potential

Argos Therapeutics today announced the publication of a manuscript in the February edition of Clinical Immunology, detailing positive immune response, safety and manufacturing data for its AGS-004 immunotherapy for HIV. AGS-004 is a product of the Company’s Arcelis™ technology, and is a personalized, RNA-loaded dendritic cell-based immunotherapy that is perfectly matched to each patient’s unique HIV viral burden. The manuscript details a clinical study in which AGS-004 was evaluated in type-1 HIV-infected adults who were being treated with antiretroviral therapy (ART).

5 Mar 2010

Study shows link between Vitamin D levels and basal cell carcinoma

A Henry Ford Hospital study has shown a link between Vitamin D levels and basal cell carcinoma, a finding that could lead researchers to better understand the development of the most common form of skin cancer.

5 Mar 2010

Scientists discover genetic cause of Quebec Platelet Disorder

For some Canadians, any cut such as from dental work or surgery can cause days or more of bleeding. Although they are not hemophiliacs, for some an ordinary bruise can balloon into the size of an orange.

4 Mar 2010

Evaluating bone defect repairs using human stem cells: NeoStem, University of Michigan enter into SRA

NeoStem, Inc., an international biopharmaceutical company with operations in the U.S. and China, announced today that it has entered into a sponsored research agreement (SRA) with the University of Michigan to evaluate bone defect repairs using human stem cells. The one-year project, beginning in March, will be funded through the proceeds of a $108,746 grant from the National Institutes of Health (NIH) under the Small Business Innovative Research Program (SBIR).

4 Mar 2010

New generation of marketing experts may be able to test products' appeal with neuromarketing

Using advanced tools to see the human brain at work, a new generation of marketing experts may be able to test a product's appeal while it is still being designed, according to a new analysis by two researchers at Duke University and Emory University.

4 Mar 2010

AB SCIEX collaborates with Mass Spectrometry Centre to improve drug discovery and development

AB SCIEX, a global leader in life science analytical technologies, today announced that it is collaborating with the University of Geneva’s Mass Spectrometry Centre to create new workflows and analytical strategies intended to significantly improve drug discovery and development.

4 Mar 2010

Study shows inhibiting critical genes may halt leukaemia cell growth

An international team of scientists studying acute forms of Leukaemia have identified a new drug target to inhibit the genes which are vital for the growth of diseased cells.

4 Mar 2010

Scientists explore household bacteria to produce top-quality cheese

The Norwegian dairy company TINE is now planning an in-depth study that will find out whether household bacteria can be used for their own sake.

4 Mar 2010

Nanoparticle growing in popularity as bactericidal agent shown to be toxic to fish: Study

A nanoparticle growing in popularity as a bactericidal agent has been shown to be toxic to fish, according to a Purdue University study.

4 Mar 2010

Brain study may lead to new forms of treatment for Alzheimer's disease

A study from EPFL's (Ecole Polytechnique F-d-rale de Lausanne) Laboratory of Neuroenergetics and Cellular Dynamics in Lausanne Switzerland, published today in the Journal of Neuroscience, may lead to new forms of treatment following a better understanding of how Amyloid-Beta found in cerebral plaques, typically present in the brain of Alzheimer's patients, may lead to neurodegeneration.

4 Mar 2010

Severe inflammatory diseases: Blocking "death messenger" might be a promising treatment

The signaling molecule CD95L, known as "death messenger," causes an inflammatory process in injured tissue after spinal cord injuries and prevents its healing. This discovery was published by scientists of the German Cancer Research Center. In mice, the researchers found out that if they switch off CD95L, the injured spinal cord heals and the animals regain better ability to move. Therefore, substances which block the death messenger might offer a new approach in the treatment of severe inflammatory diseases.

4 Mar 2010

University of Calgary chemist finds potential tool to measure impact of nanoparticles on human health

University of Calgary chemistry professor David Cramb is a step closer to helping solve a complex problem in nanotechnology: the impact nanoparticles have on human health and the environment.

4 Mar 2010

Researchers reveal new details of the mechanisms of ion channel inactivation

Two studies by researchers at The Johns Hopkins University School of Medicine reveal new details of the mechanisms of ion channel inactivation. The papers appear in the March issue of The Journal of General Physiology (www.jgp.org).

4 Mar 2010

Boosting immune response to vaccinations: Role of aluminium adjuvants

An imminent publication in Trends in Immunology by a leading researcher in the bioinorganic chemistry of aluminium, Dr Christopher Exley, Reader in Bioinorganic Chemistry at The Birchall Centre, Keele University in Staffordshire, has now gone some way to giving the fullest possible explanation of how aluminium adjuvants work in boosting the immune response to vaccination.

4 Mar 2010

Exposure to blue-violet light may enhance cell growth in wound sites

Today, during the 39th Annual Meeting of the American Association for Dental Research, convening at the Walter E. Washington Convention Center in Washington, DC, lead researcher C. Millan (U.S. Army Dental Corps, Martinez, Georgia) will present a poster of a study titled "A Novel In Vitro Model for Light-Induced Wound Healing."

4 Mar 2010

TNFerade's suppression of cancer metastases: Mechanisms revealed

GenVec, Inc. announced the publication of new preclinical research revealing mechanisms by which TNFerade(TM) suppresses cancer metastases through activation of the immune system.

4 Mar 2010

Study: Bacteria, fungi and other microbes live in our gut are essential contributors to good health

The thousands of bacteria, fungi and other microbes that live in our gut are essential contributors to our good health. They break down toxins, manufacture some vitamins and essential amino acids, and form a barrier against invaders. A study published today in Nature shows that, at 3.3 million, microbial genes in our gut outnumber previous estimates for the whole of the human body.

4 Mar 2010

Cryoablation kills breast tumors in mice

Freezing a cancer kills it in its place, and also appears to generate an immune response that helps stop the cancer's spread, leading to improved survival rates over surgery, according to a new study in mice from researchers at the University of Michigan Comprehensive Cancer Center.

4 Mar 2010

Cornell researchers find new protein that may help control mosquitoes from spreading diseases

Cornell researchers have found a protein that may lead to a new way to control mosquitoes that spread dengue fever, yellow fever and other diseases when they feed on humans: Prevent them from urinating as they feed on blood.

4 Mar 2010

Medical Science News

Humacyte, Xcellerex collaborate to develop novel vascular graft for transplantation technologies

Argos Therapeutics' AGS-004 immunotherapy for HIV demonstrates clinical and commercial potential

Study shows link between Vitamin D levels and basal cell carcinoma

Scientists discover genetic cause of Quebec Platelet Disorder

Evaluating bone defect repairs using human stem cells: NeoStem, University of Michigan enter into SRA

New generation of marketing experts may be able to test products' appeal with neuromarketing

AB SCIEX collaborates with Mass Spectrometry Centre to improve drug discovery and development

Study shows inhibiting critical genes may halt leukaemia cell growth

Scientists explore household bacteria to produce top-quality cheese

Nanoparticle growing in popularity as bactericidal agent shown to be toxic to fish: Study

Brain study may lead to new forms of treatment for Alzheimer's disease

Severe inflammatory diseases: Blocking "death messenger" might be a promising treatment

University of Calgary chemist finds potential tool to measure impact of nanoparticles on human health

Researchers reveal new details of the mechanisms of ion channel inactivation

Boosting immune response to vaccinations: Role of aluminium adjuvants

Exposure to blue-violet light may enhance cell growth in wound sites

TNFerade's suppression of cancer metastases: Mechanisms revealed

Study: Bacteria, fungi and other microbes live in our gut are essential contributors to good health

Cryoablation kills breast tumors in mice

Cornell researchers find new protein that may help control mosquitoes from spreading diseases

How can microdialysis benefit drug development

Global and Local Efforts to Take Action Against Hepatitis

Addressing Important Cardiac Biology Questions with Shotgun Top-Down Proteomics

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