Molecular & Structural Biology

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Research reveals new mechanism which could lead to premature aging in mother cells

Researchers from the University of Seville and the Andalusian Center of Molecular Biology and Regenerative Medicine, have discovered a new mechanism that makes it possible to understand premature aging in cells with asymmetrical cell division, as is the case with mother cells.

30 Sep 2019

Cellular aging associated with structural changes in the brain

Telomeres are protective caps at the ends of chromosomes that become shorter with each cell division. If they become so short that the genes they protect could be damaged, the cell stops dividing and renewing.

27 Sep 2019

Functional three-organoid stem cell system could lead to unprecedented advances for precision medicine

Using iPS cells, a Japanese research group has successfully grown a connected set of organs at the same time, including a liver and a pancreas connected by a bile duct.

27 Sep 2019

Scientists use ultrasound to detect active genes in live cells

A startling new study shows that ultrasound can help scientists to understand whether specific genes are in the active or inactive state in live cells.

27 Sep 2019

Closely spaced habitats are more likely to be used by mosquitoes to lay eggs

Patches of standing water that are close together are more likely to be used by mosquitoes to lay eggs in than patches that are farther apart, according to a new study from the University of Georgia. The findings, recently published in Oecologia, have implications for human and animal health.

26 Sep 2019

Mechanisms behind antibiotic resistance captured on video for the first time

Scientists have established the cause of antibiotic-resistance in bacteria on video, and the findings contradict previous beliefs.

26 Sep 2019

Temporal fluctuations in protein concentrations can determine fate of stem cells

How do temporal variations in protein concentrations affect biology? It's a question that biologists have only recently begun to address, and the findings are increasingly showing that random temporal changes in the amount of certain proteins play a direct and significant role on biological processes.

26 Sep 2019

Researchers identify novel genetic variants linked to plasma lipid levels and cardiovascular risk

An international research team has identified several novel genetic variants associated with plasma levels of lipid species and cardiovascular disease risk in humans.

26 Sep 2019

New technique can rapidly image synaptic proteins at high resolution

Our brains contain millions of synapses -- the connections that transmit messages from neuron to neuron. Within these synapses are hundreds of different proteins, and dysfunction of these proteins can lead to conditions such as schizophrenia and autism.

26 Sep 2019

Researchers investigate relationship between immune defenses and body size

What species is better at fighting an infection, a mouse or an elephant? Body size is one of the most noticeable differences among species, but relationships between immune defenses and body size have largely been unstudied.

25 Sep 2019

Scientists use new single-cell genetic technique to tackle potential drug resistance

Using a new technique that can identify genetic profiles of individual cells, University of Notre Dame researchers modeled a breast cancer tumor's potential resistance to a drug, and then identified a drug combination that reversed that resistance.

25 Sep 2019

Monitoring the Human Proteome using diaPASEF

In this interview, Dr. Hannes Röst describes how his lab are using diaPASEF to monitor the human proteome throughout a person's lifetime, and how machine learning could be used to analyze the data.

From Bruker Life Sciences Mass Spectrometry 25 Sep 2019

Reactivating ‘tumor suppressor’ genes could offer new therapeutic approach for cancer

Scientists have developed a method which is able to switch ‘tumor suppressor’ genes back on after they have been silenced by cancer cells.

25 Sep 2019

Improved mapping of genomes from 1,000 Swedish individuals

In so-called whole genome sequencing, surveys are made of the total genome of an individual. It is still relatively rare in healthcare today, but it occurs at an increasing rate, for example in order to make an accurate diagnosis in the case of a rare disease.

25 Sep 2019