Molecular & Structural Biology

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Atlas of the nervous system provides new clues about origin of neurological diseases

Researchers at Karolinska Institutet have created a systematic and detailed map of the cell types of the mouse nervous system.

9 Aug 2018

Research findings open door to promising HIV treatments

New research provides details of how the structure of the HIV-1 virus is assembled, findings that offer potential new targets for treatment.

9 Aug 2018

Structure of a long-chain lipid that keeps our tears clear revealed

As anyone who has experienced an annoying alternation between dry and watery eyes can confirm, tears alone aren't enough to keep the eye from drying out. A microscopically thin film of oils known as the tear film lipid layer is key to preventing the tear film from evaporating.

9 Aug 2018

Nobel laureate Dr. Fraser Stoddart to deliver Wallace H. Coulter Lecture at Pittcon 2019

The Pittcon Program Committee is extremely pleased to announce that Fraser Stoddart, a Nobel Prize in Chemistry 2016 recipient, will deliver the 2019 Wallace H. Coulter Lecture.

7 Aug 2018

Social environment influences individuality of mice

Individuality is not exclusive to humans. Though this idea was previously rebutted by biologists, today it is accepted that individuality is found in all animal species. It is defined as all the behavior differences between individuals of a single species that are relatively stable over time.

6 Aug 2018

Discovery of new epithelial lung cell type may affect cystic fibrosis therapy

Scientists have discovered a new type of cell in the human respiratory tract called the pulmonary ionocyte, and linked it to cystic fibrosis.

3 Aug 2018

Genome-wide association study identifies 151 genes for atrial fibrillation

Drawing on genomic data from more than one million individuals, researchers from the University of Michigan have led a large collaborative effort to discover as-yet unknown genetic risk factors for atrial fibrillation: an irregular, often rapid heart rate affecting millions of Americans and more than 30 million people worldwide.

3 Aug 2018

Scientists map regulatory landscape of mouse genome at single-cell resolution

Scientists have completed a major effort to map the regulatory landscape of the mouse genome at a single-cell resolution.

2 Aug 2018

New probe allows identification of cancer stem cells in situ

A fluorescent molecular probe that targets cancer stem cells has been developed at the University of Illinois at Urbana-Champaign.

2 Aug 2018

Scientists uncover molecular 'switch' that may control the benefits of exercise

Some people respond well to both aerobic exercise and strength training, while others don't. And some of us respond well to only one of those things, but not both. Scientists at Joslin Diabetes Center now have uncovered a surprising molecular "switch" that may help to explain why this happens.

2 Aug 2018

Breakthrough in stem cell research could lead to cure for cystic fibrosis

Researchers have successfully proved that gene therapy can be used to convert adult stem cells into functioning lung cells for the treatment of cystic fibrosis

2 Aug 2018

Researchers use guide RNAs to improve base editing system

Researchers have used guide RNAs to improve the adenine base editing (ABE) system, used by scientists to alter genetic codes in animal models of disease.

1 Aug 2018

High Throughput Biophysical Screening for Development and Formulation of Biologics

In this interview, John Champagne, Ph.D. Senior Applications Scientist and Northeast Regional Manager for Wyatt Technology, talks to News-Medical about

From Waters | Wyatt Technology 1 Aug 2018

Computational platform predicts how to convert one cell type into another

Researchers have developed a computational platform that predicts how one subtype of cells can be converted into another subtype.

30 Jul 2018

New approach shows important role of microRNAs in papillomavirus life cycle

The discovery of microRNAs encoded by papillomaviruses supports the important role of these small molecules in persistent infection, according to a study published July 26 in the open-access journal PLOS Pathogens.

27 Jul 2018

Desert bush spider toxin helps researchers to better understand human and insect biology

A toxin from the desert bush spider is helping researchers understand more about human and insect biology, which could lead to new treatments for health conditions and bee-friendly insecticides.

27 Jul 2018

Study shows how organs acquire very complex yet stable shapes

Researchers from the Department of Cellular Biology at the University of Seville and Seville Institute of Biomedicine have shown that epithelial cells, which are those that cover the surfaces of many organs, adopt a new, previously undescribed geometric shape, the scutoid, so that tissue can curve.

27 Jul 2018