Molecular & Structural Biology

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UZH scientists identify enzyme that controls cell division

When a cell divides, its constituents are usually evenly distributed among the daughter cells. UZH researchers have now identified an enzyme that guarantees that cell constituents that are concentrated in organelles without a membrane are properly distributed.

12 Jul 2018

Streck ARM-D Kits detect more antibiotic resistance than comparable tests

Streck, Inc., received great interest in Streck ARM-D Kits after its poster presentation on improved methodology for detection of antibiotic resistance in Gram-negative bacteria at ECCMID 2018 in Madrid.

12 Jul 2018

Research reveals new gears in the circadian clock

A long-studied factor controlling human sleep cycles actually has two forms, one that keeps a key protein stable and another that promotes its degradation.

12 Jul 2018

Researchers discover why CRISPR gene editing sometimes fails

A study has explained for the first time why the CRISPR gene editing tool fails to work in 15% cases, and has suggested methods to prevent this.

11 Jul 2018

Researchers uncover molecular drivers of a deadly pediatric cancer

Researchers have made important discoveries about the molecular mechanisms driving acute myeloid leukemia (AML), a deadly pediatric cancer.

11 Jul 2018

New approach sheds light on effects of drugs on cancer cells

A new approach established at the University of Zurich sheds light on the effects of anti-cancer drugs and the defense mechanisms of cancer cells.

11 Jul 2018

Researchers find ATM protein that can trigger production of antioxidants

One reason we're supposed to eat a variety of colorful fruits and vegetables is because they contain nutritious compounds called antioxidants.

11 Jul 2018

Mature kidney podocytes for developing cell therapies and drug discovery

Human stem cells are of great interest in the fields of regenerative medicine and medical research because they reproduce indefinitely and can differentiate into every other cell type found in the body.

11 Jul 2018

Stem cell study brings scientists closer to understanding schistosomiasis

Scientists have made an important discovery that could lead to the development of new treatments for schistosomiasis, a common parasitic disease.

10 Jul 2018

Newly discovered nanobody holds promise to advance targeted therapies for several diseases

Researchers from Case Western Reserve University School of Medicine have found a nanobody that holds promise to advance targeted therapies for a number of neurological diseases and cancer.

10 Jul 2018

Researchers discover mechanism that shuts down cell-to-cell communications pathway

Cellular functions rely on several communications networks that allow cells to rapidly respond to signals affecting the organism.

10 Jul 2018

Fluorescent zebrafish genes provide clues about neuroblastoma

Researchers have created transgenic zebrafish that could help them understand how neuroblastoma, a common pediatric cancer, develops.

10 Jul 2018

UT Southwestern researchers uncover body's microreactors for innate immunity

A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body's first response to infection, UT Southwestern researchers report. The work, reported today in the journal Science, could lead to novel treatments for infections, autoimmune disease, and cancer.

9 Jul 2018

Scientists develop novel method of producing pluripotent stem cells

Scientists have developed a modified CRISPR tool that can stimulate the de-differentiation of somatic cells into induced pluripotent stem cells,

6 Jul 2018

Gene therapy study shows promise for chronic kidney disease

A study has shown that a viral vector can deliver genetic material to damaged kidney cells, potentially providing a treatment that can slow or reverse chronic kidney disease.

6 Jul 2018

Effective molecular labeling to identify biomedical implants inside living being

A team of researchers at CNRS, Aix-Marseille Université and Université Paris 13 has demonstrated effective molecular labeling to unequivocally identify biomedical implants, even after a prolonged period inside the living being. These results were published in Angewandte Chemie International Edition on July 5, 2018.

6 Jul 2018

Researchers unravel molecular code that shapes complex networks in the brain

The brain is an enormously complex organ. Understanding how billions of brain cells succeed in making precise connections is a major challenge for neuroscientists.

6 Jul 2018

Drug combinations alter effectiveness of antibiotics

The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives.

4 Jul 2018

Study sheds light on how good bacteria prevent gut inflammation

Researchers at the Baylor College of Medicine have identified the mechanism by which good bacteria (microbiota) help maintain a healthy intestine.

4 Jul 2018

Research elucidates maturation of cancer-causing miRNAs

An international research team led by Helmholtz Zentrum München, Technical University of Munich and the University of Edinburgh has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation.

4 Jul 2018