Molecular & Structural Biology

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Study reveals RNA editing regulator involved in cancer development

Researchers have discovered a bidirectional regulator of adenosine-to-inosine (A-to-I) RNA editing that could serve as a new cancer drug target.

21 Aug 2018

Scientists create universal blood type using enzymes from gut bacteria

Scientists have discovered enzymes from species of the gut microbiome that can convert A and B blood types into the universal type O.

21 Aug 2018

Study uncover metabolic network controlled by the ‘circadian clock’ of muscle cells

How do muscle cells prepare for the particular metabolic challenges of the day? Scientists at Helmholtz Zentrum München and Ludwig-Maximilians-Universität München, members of the German Center for Diabetes Research, have investigated this question and published their results in 'PLOS Biology'.

21 Aug 2018

Micro-flow model reveals complex interactions between the brain’s blood vessels and nerve cells

Micro-flow models of the blood-brain barrier and the brain reveal for the first time complex metabolic interactions between the brain's blood vessels and nerve cells. The findings are published by an international team of researchers, including from Karolinska Institutet and the Royal Institute of Technology, in the journal Nature Biotechnology.

20 Aug 2018

Study reveals why individuals carrying identical gene mutations have varying disease severity

Researchers at the New York Genome Center and Columbia University have uncovered a molecular mechanism behind one of biology's long-standing mysteries: why individuals carrying identical gene mutations for a disease end up having varying severity or symptoms of the disease.

20 Aug 2018

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

ALS -- amyotrophic lateral sclerosis -- is a neurodegenerative disease that attacks motor neurons in the brain and spinal cord, slowly robbing its victims of their ability to walk, talk, breathe and swallow.

20 Aug 2018

Study unravels cellular and molecular mechanisms behind dermal condensate formation

Hair growth is regulated by a small cluster of hair-specific fibroblasts, the dermal papilla. But exactly how dermal papilla forms has remained elusive until now.

20 Aug 2018

Understanding How Antibodies Shape the Gut Microbiome

Dr. Keiichiro Suzuki discusses the importance of IgA in the human body, and his recent research study, which showed that IgA interacts with the gut microbiome and promotes the growth of healthy bacteria.

20 Aug 2018

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

A few little cells that are different from the rest can have a big effect. For example, individual cancer cells may be resistant to a specific chemotherapy--causing a relapse in a patient who would otherwise be cured. In the journal Angewandte Chemie, scientists have now introduced a microfluidics-based chip for the manipulation and subsequent nucleic-acid analysis of individual cells.

17 Aug 2018

New technique detects, measures, analyzes unevenly charged biomolecules

In clinical diagnostics, it is critical to monitor biomolecules in a simple, rapid and sensitive way. Clinicians most often monitor antibodies because these small proteins attach to antigens, or foreign substances, we face every day.

17 Aug 2018

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Excessive body fat is associated with negative effects on female fertility and pregnancy. In mice, maternal obesity impairs proper development of egg precursor cells called oocytes.

17 Aug 2018

Experts advise against universal genomic screening of newborns

In a new report, experts at The Hastings Center advise against genomic screening of newborns, despite it's potential for providing life long personalized care.

16 Aug 2018

Scientists uncover key control mechanism of DNA replication

Researchers from Osaka University in Japan have uncovered a key control mechanism of DNA replication with potential implications for better understanding how cells maintain genetic information to prevent diseases or cancer.

16 Aug 2018

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

A car accident leaves an aging patient with severe muscle injuries that won't heal. Treatment with muscle stem cells from a donor might restore damaged tissue, but doctors are unable to deliver them effectively. A new method may help change this.

16 Aug 2018

Study reveals role of RUNX proteins in DNA repair

A study by researchers from the Cancer Science Institute of Singapore at the National University of Singapore has revealed that RUNX proteins are integral to efficient DNA repair via the Fanconi Anemia pathway.

15 Aug 2018

Researchers discover new promising target point for cancer and diabetes therapies

If certain signaling cascades are misregulated, diseases like cancer, obesity and diabetes may occur. A mechanism recently discovered by scientists at the Leibniz-Forschungsinstitut für Molekulare Pharmakologie in Berlin and at the University of Geneva has a crucial influence on such signaling cascades and may be an important key for the future development of therapies against these diseases.

15 Aug 2018

Molecular & Structural Biology

Study reveals RNA editing regulator involved in cancer development

Scientists create universal blood type using enzymes from gut bacteria

Study uncover metabolic network controlled by the ‘circadian clock’ of muscle cells

Micro-flow model reveals complex interactions between the brain’s blood vessels and nerve cells

Study reveals why individuals carrying identical gene mutations have varying disease severity

Study shows that rogue proteins may underlie some ALS and frontotemporal dementia cases

Study unravels cellular and molecular mechanisms behind dermal condensate formation

Understanding How Antibodies Shape the Gut Microbiome

Scientists introduce microfluidics-based chip for manipulation and analysis of single cells

New technique detects, measures, analyzes unevenly charged biomolecules

Researchers describe link between poor oocyte development and oxidative stress in obese mice

Experts advise against universal genomic screening of newborns

Scientists uncover key control mechanism of DNA replication

Researchers develop molecular matrix that delivers healing stem cells to injured elderly muscles

Study reveals role of RUNX proteins in DNA repair

Researchers discover new promising target point for cancer and diabetes therapies

Cruciferous vegetables found to protect against colon cancer in mice

Researchers move closer to finding potential soft spot in drug-resistant tuberculosis

Study provides insight into link between sleep apnea and lipid metabolism

Scientists reveal role of 'junk DNA' in cancer dissemination

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