Molecular & Structural Biology

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UT Southwestern researchers uncover body's microreactors for innate immunity

A DNA-sensing enzyme forms droplets that act as tiny bioreactors creating molecules to stimulate innate immunity – the body's first response to infection, UT Southwestern researchers report. The work, reported today in the journal Science, could lead to novel treatments for infections, autoimmune disease, and cancer.

9 Jul 2018

Scientists develop novel method of producing pluripotent stem cells

Scientists have developed a modified CRISPR tool that can stimulate the de-differentiation of somatic cells into induced pluripotent stem cells,

6 Jul 2018

Gene therapy study shows promise for chronic kidney disease

A study has shown that a viral vector can deliver genetic material to damaged kidney cells, potentially providing a treatment that can slow or reverse chronic kidney disease.

6 Jul 2018

Effective molecular labeling to identify biomedical implants inside living being

A team of researchers at CNRS, Aix-Marseille Université and Université Paris 13 has demonstrated effective molecular labeling to unequivocally identify biomedical implants, even after a prolonged period inside the living being. These results were published in Angewandte Chemie International Edition on July 5, 2018.

6 Jul 2018

Researchers unravel molecular code that shapes complex networks in the brain

The brain is an enormously complex organ. Understanding how billions of brain cells succeed in making precise connections is a major challenge for neuroscientists.

6 Jul 2018

Drug combinations alter effectiveness of antibiotics

The effectiveness of antibiotics can be altered by combining them with each other, non-antibiotic drugs or even with food additives.

4 Jul 2018

Study sheds light on how good bacteria prevent gut inflammation

Researchers at the Baylor College of Medicine have identified the mechanism by which good bacteria (microbiota) help maintain a healthy intestine.

4 Jul 2018

Research elucidates maturation of cancer-causing miRNAs

An international research team led by Helmholtz Zentrum München, Technical University of Munich and the University of Edinburgh has used an integrated structural biological approach to elucidate the maturation of a cancer-causing microRNA in gene regulation.

4 Jul 2018

Seeing the Unexpected: Regulatory T Cells and Basophils

Dr. Jagadeesh Bayry from INSERM discusses his recent research in the field of immunology, and how T regulatory cells activate, rather than suppress, basophils.

4 Jul 2018

Specific type of satellite RNA induces breast cancer, shows study

Only some of us have satellite TV in our homes, but all of us have satellite DNA in cells in our bodies. Working copies of satellite DNA are high in certain types of cancer, such as breast and ovarian.

4 Jul 2018

Researchers develop switch that can control genome editing

Researchers have developed a biological switch that reliably triggers protein expression and enables the control of genome editing tools.

3 Jul 2018

Mayo researchers determine how DNA repair protein gets to the site of damage

Damage to DNA is a daily occurrence but one that human cells have evolved to manage. Now, in a new paper published in Nature Structural & Molecular Biology, Mayo researchers have determined how one DNA repair protein gets to the site of DNA damage. The authors say they hope this discovery research will help identify new therapies for ovarian cancer.

3 Jul 2018