Molecular & Structural Biology

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High Throughput Biophysical Screening for Development and Formulation of Biologics

In this interview, John Champagne, Ph.D. Senior Applications Scientist and Northeast Regional Manager for Wyatt Technology, talks to News-Medical about

From Waters | Wyatt Technology 1 Aug 2018

Computational platform predicts how to convert one cell type into another

Researchers have developed a computational platform that predicts how one subtype of cells can be converted into another subtype.

30 Jul 2018

New approach shows important role of microRNAs in papillomavirus life cycle

The discovery of microRNAs encoded by papillomaviruses supports the important role of these small molecules in persistent infection, according to a study published July 26 in the open-access journal PLOS Pathogens.

27 Jul 2018

Desert bush spider toxin helps researchers to better understand human and insect biology

A toxin from the desert bush spider is helping researchers understand more about human and insect biology, which could lead to new treatments for health conditions and bee-friendly insecticides.

27 Jul 2018

Study shows how organs acquire very complex yet stable shapes

Researchers from the Department of Cellular Biology at the University of Seville and Seville Institute of Biomedicine have shown that epithelial cells, which are those that cover the surfaces of many organs, adopt a new, previously undescribed geometric shape, the scutoid, so that tissue can curve.

27 Jul 2018

Fucose-based food supplement could be used to stop the spread of norovirus in children's hospitals

Norovirus is the most common cause of gastroenteritis worldwide; it causes tens hundreds of thousands of deaths each year and is particularly risky for children under 3 years old.

27 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

Scientists use new drug discovery system to target Huntington’s Disease

Scientists have used a new drug discovery system to specifically target phosphatases in Huntington's, which were previously thought to be undruggable.

27 Jul 2018

New drug discovery system allows scientists to target ‘undruggable’ enzymes

A new drug discovery system allows scientists to specifically target members of an important family of enzymes, called phosphatases, which were previously considered mostly "undruggable".

27 Jul 2018

Scientists discover gene that predicts arthritis severity

Scientists have discovered a new gene that is associated with disease severity in rheumatoid arthritis. HIP1 produces an inflammatory molecule which drives RA.

26 Jul 2018

Small RNA in sperm shown to be essential for embryonic development

New research has shown that small RNA in sperm is essential for embryo implantation and embryonic development. The findings will be used to optimize IVF.

26 Jul 2018

Study reveals key role of actin cytoskeletal dynamics in supporting immune cell function

In order to move, a body needs a strong scaffold. This is not only true on a macroscopic level, where animals rely on skeletons to support their muscles.

26 Jul 2018

Researchers find that IgM antibody could protect against HIV-1

A team of scientists from Texas Biomedical Research Institute have homed in on an antibody that could protect against infection with HIV-1.

24 Jul 2018

Bioengineers build 3D model of human heart ventricle

Harvard University researchers have bioengineered a three-dimensional model of a human left heart ventricle that could be used to study diseases, test drugs and develop patient-specific treatments for heart conditions such as arrhythmia.

24 Jul 2018

Discovery about how malaria moves could lead to new therapies

Researchers have made an important discovery about how Plasmodium falciparum (the parasite that causes malaria) is able to evade capture by the immune system.

23 Jul 2018

Researchers design proteins that can self-assemble into complex structures

A collaborative research team based in Japan has designed new proteins that can self-assemble into the complex structures underlying biological organisms, laying the groundwork for leading-edge applications in biotechnology.

20 Jul 2018

Scientists discover protein regulator of myelin production

Scientists have made an important discovery about the role of a protein called PRMT5 in the production of myelin.

19 Jul 2018

Study identifies RNA molecules that regulate male hormones in prostate cancer

In most cases of prostate cancer, tumor cell growth is stimulated by the action of male hormones, or androgens, such as testosterone and dihydrotestosterone.

19 Jul 2018