Molecular & Structural Biology

RSS

CRISPR technology shows potential as a “molecular recorder” through DNA encoded movie

The researchers from Harvard University, Seth L. Shipman, Jeff Nivala, Jeffrey D. Macklis and George M. Church, believe that their study is a major step forward to a "molecular recorder" that may someday make it possible to get read-outs, has published online their proof-of-concept on July 12, 2017, in the journal Nature.

14 Jul 2017

New technique reveals detailed structure of sweat glands

The basic structure of human sweat glands consists of a coiled secretory region deep in the skin and then a tube or duct that conveys the sweat to a pore at the skin surface.

10 Jul 2017

Novel technique analyzes sperm morphology and motility in embryo formation process

The research, presented at the European Society of Human Reproduction and Embryology annual conference, which ends today in Geneva, Switzerland, describes for the first time the use of an experimental technique that has made it possible to analyze the functioning of human sperm in contact with the cytoplasmic content of the eggs in vitro.

7 Jul 2017

Researchers discover how new molecular scissors unzip and cleave DNA with high accuracy

Researchers from the University of Copenhagen (Denmark), led by the Spanish researcher Guillermo Montoya, have discovered how Cpf1, new molecular scissors unzip and cleave DNA.

6 Jul 2017

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

New research by scientists at the MRC Laboratory of Molecular Biology in the United Kingdom and Indiana University School of Medicine gives the most detailed view yet of tau protein structures found in Alzheimer's disease.

6 Jul 2017

Study indicates new element involved in genome instability

Genome instability is the main risk factor in the development of tumours in humans. Understanding how, where, when and why these mutations are produced in DNA is one of the great objectives of the global scientific community.

30 Jun 2017

Research provides new insights into how telomeres regulate cellular senescence

Researchers at the Institute of Molecular Biology and Johannes Gutenberg University Mainz have further uncovered the secrets of telomeres, the caps that protect the ends of our chromosomes.

30 Jun 2017

Research presents crystal structure of enzyme implicated in cancer, neurodegenerative diseases

A Stony Brook University-led team of researchers has determined the structure of a key enzyme involved with cell growth regulation in cancer and neurodegenerative diseases, including Alzheimer's disease.

28 Jun 2017

Morgridge researchers reveal complex viral replication process in unprecedented detail

In the fight against the viruses that invade everyday life, seeing and understanding the battleground is essential. Scientists at the Morgridge Institute for Research have, for the first time, imaged molecular structures vital to how a major class of viruses replicates within infected cells.

27 Jun 2017

Researchers develop new technique to capture neuron activity

Many cognitive processes, such as decision-making, take place within seconds or minutes. Neuroscientists have longed to capture neuron activity during such tasks, but that dream has remained elusive -- until now.

27 Jun 2017

Researchers uncover three-dimensional structure of tetanus toxin protein

"Our discovery could be used to design new medicines", says Pål Stenmark, Associate Professor at the Department of Biochemistry and Biophysics, Stockholm University.

27 Jun 2017

Combined effect of genetic change and ozone exposure could increase risk for autism

A new analysis shows that individuals with high levels of genetic variation and elevated exposure to ozone in the environment are at an even higher risk for developing autism than would be expected by adding the two risk factors together.

23 Jun 2017

Two-test combination accurately identifies benign pancreatic lesions

When performed in tandem, two molecular biology laboratory tests distinguish, with near certainty, pancreatic lesions that mimic early signs of cancer but are completely benign.

23 Jun 2017

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

The leading cause of acute gastroenteritis linked to eating raw seafood disarms a key host defense system in a novel way: It paralyzes a cell's skeleton, or cytoskeleton.

23 Jun 2017

Could the mTOR pathway be used to protect against cancer?

The mTOR pathway is probably the main pathway in humans and other animals that drives growth. That is, the accumulation of mass and adding mass to make an organism bigger by both making more cells, and making cells grow and become bigger.

22 Jun 2017

Researchers create new camera that can register fast processes in transparent specimens

Researchers from ITMO University have built a setup for recording holograms of tiny objects like living cells with a femtosecond speed. The new method allows one to reconstruct phase topography of a studied sample according to deformations that emerge in a laser pulse when it passes through the specimen.

22 Jun 2017

Researchers examine formation of functional amyloids by bacteria in real time

A team of scientists from the VIB lab of Han Remaut and the lab of Yves Dufrêne at UCL Louvain-La-Neuve collaborated on a study of functional amyloids -protein aggregates with the typical amyloid structure that do not lead to disease but rather serve a dedicated biological function.

21 Jun 2017

Cells key to blood vessel formation can also produce tumors and enable their spread

While it's widely held that tumors can produce blood vessels to support their growth, scientists now have evidence that cells key to blood vessel formation can also produce tumors and enable their spread.

20 Jun 2017

Exposure to light at night suppresses biting, manipulates flight behavior in mosquitoes

Scientists at the University of Notre Dame have found that exposure to just 10 minutes of light at night suppresses biting and manipulates flight behavior in the Anopheles gambiae mosquito, the major vector for transmission of malaria in Africa, according to new research published in the journal Parasites and Vectors.

16 Jun 2017

Findings may contribute to better understanding of aging and cancer development

A team of researchers led by Dr. Dennis Kappei, a Special Fellow from the Cancer Science Institute of Singapore at the National University of Singapore, has discovered the role of the protein ZBTB48 in regulating both telomeres and mitochondria, which are key players involved in cellular aging.

14 Jun 2017

Molecular & Structural Biology

CRISPR technology shows potential as a “molecular recorder” through DNA encoded movie

New technique reveals detailed structure of sweat glands

Novel technique analyzes sperm morphology and motility in embryo formation process

Researchers discover how new molecular scissors unzip and cleave DNA with high accuracy

Scientists provide detailed view of tau protein structures found in Alzheimer's disease

Study indicates new element involved in genome instability

Research provides new insights into how telomeres regulate cellular senescence

Research presents crystal structure of enzyme implicated in cancer, neurodegenerative diseases

Morgridge researchers reveal complex viral replication process in unprecedented detail

Researchers develop new technique to capture neuron activity

Researchers uncover three-dimensional structure of tetanus toxin protein

Combined effect of genetic change and ozone exposure could increase risk for autism

Two-test combination accurately identifies benign pancreatic lesions

Pathogen linked to seafood poisoning disarms key host defense system by paralyzing cell's skeleton

Could the mTOR pathway be used to protect against cancer?

Researchers create new camera that can register fast processes in transparent specimens

Researchers examine formation of functional amyloids by bacteria in real time

Cells key to blood vessel formation can also produce tumors and enable their spread

Exposure to light at night suppresses biting, manipulates flight behavior in mosquitoes

Findings may contribute to better understanding of aging and cancer development

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Latest Life Science News