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ACE inhibitors show no benefit in reducing chemotherapy-induced heart damage

Patients who took an angiotensin-converting enzyme (ACE) inhibitor while undergoing cancer treatment with high-dose anthracycline chemotherapy did not show any difference in troponin T levels, a biomarker associated with heart damage, at one month after their last chemotherapy dose compared with those who did not take an ACE inhibitor, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Study shows reduced bleeding risk with ticagrelor monotherapy after percutaneous coronary intervention

People who have had a heart attack or who are at risk for a heart attack and who stopped taking aspirin alongside the P2Y12 inhibitor ticagrelor one month after undergoing percutaneous coronary intervention (PCI) saw a significantly reduced risk of clinically meaningful bleeding with no increased risk of clotting-related adverse events at 12 months compared with patients who continued taking aspirin and ticagrelor for a full year, in a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Lerodalcibep reduces LDL cholesterol by over 50% in high-risk patients

Among patients at high or very high risk for a heart attack or stroke, the addition of the investigational drug lerodalcibep to standard cholesterol-lowering medication for one year reduced LDL, or "bad" cholesterol, levels by more than half on average, compared with a placebo.

8 Apr 2024

Study: Empagliflozin shows mixed results in heart attack patients

Use of the sodium glucose cotransporter-2 (SGLT-2) inhibitor empagliflozin following a heart attack did not show a significant benefit in reducing overall heart failure hospitalizations or death from any cause, according to a study presented at the American College of Cardiology's Annual Scientific Session.

8 Apr 2024

Pioneering vaccine strategy promises to outmaneuver antimicrobial resistance

Study introduces Reverse Vaccine Development as a strategic approach to identify correlates of protection early in vaccine development against antimicrobial-resistant pathogens, aiming to mitigate risks such as significant phase-III clinical trial failures.

7 Apr 2024

Study questions routine use of beta blockers after heart attack

Taking beta blockers after a heart attack did not significantly reduce the risk of death or a second heart attack among people with normal heart pumping ability, as indicated by an ejection fraction of 50% or higher, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Study shows promise of zilebesiran injection in reducing systolic blood pressure

A single subcutaneous injection of the investigational drug zilebesiran, when added to existing treatment with a standard antihypertensive medication, reduced systolic blood pressure by between 4 to 12 mmHg on average at three months in patients whose blood pressure had remained uncontrolled despite compliance with their medication regimen, according to a study presented at the American College of Cardiology's Annual Scientific Session.

7 Apr 2024

Oral spray-based vaccine is a potential alternative to antibiotic treatments for recurrent UTIs

Recurrent Urinary Tract Infections (UTIs) can be prevented for up to nine years in more than half of people given an oral spray-based vaccine and is a potential alternative to antibiotic treatments, finds research.

7 Apr 2024

Acetaminophen at moderate doses may alter heart function

The common painkiller acetaminophen was found to alter proteins in the heart tissue when used regularly at moderate doses, according to a new study conducted in mice.

7 Apr 2024

World Health Day 2024: Championing Universal Health Rights with AZoNetwork

World Health Day 2024.

5 Apr 2024

Biden is right about $35 insulin cap but exaggerates prior costs for Medicare enrollees

The cost of insulin in the United States has risen considerably in recent years, with some estimates finding that Americans have paid around 10 times as much for the drug as people in other developed countries.

5 Apr 2024

New model predicts kidney injury risk in cancer patients on cisplatin

Researchers have developed a new model predicting severe acute kidney injury in patients treated with cisplatin, incorporating factors like hypomagnesemia to improve patient care and outcomes.

3 Apr 2024

Certain progestogens linked to higher brain tumor risk in women, study suggests

Study finds long-term use of specific progestogens increases the risk of benign brain tumors in women, while short-term use and other progestogens do not.

3 Apr 2024

Statins slightly up diabetes risk but cardiovascular benefits remain, finds study

Statin therapy modestly increases diabetes diagnoses but offers substantial cardiovascular benefits, outweighing the slight rise in glycemia, especially in those near diabetes diagnostic thresholds.

2 Apr 2024

New report on HIV drug resistance: Challenges and recommendations

The World Health Organization's (WHO) latest HIV Drug Resistance (HIVDR) Report tells us where drug resistance is growing and offers recommendations for countries to monitor and respond to the potential challenges.

1 Apr 2024

Polypills prove effective in reducing cardiovascular disease and mortality

A new study from researchers at Washington University Medical School in St. Louis bolsters previous findings that polypills are beneficial in preventing heart attacks and strokes and reducing deaths among people with cardiovascular risk factors, including high blood pressure and high cholesterol.

29 Mar 2024

Statins linked to slight diabetes risk but benefits outweigh the concerns

Statin use is associated with a moderate, dose-dependent increase in the risk of new-onset diabetes, particularly in individuals close to the diabetes threshold, yet the cardiovascular benefits of statin therapy remain substantial.

28 Mar 2024

Researchers discover a safer and more efficient technique for testing new drugs

McGill researchers have discovered a safer and more efficient technique for testing new drugs while they are in development.

28 Mar 2024

KFF Health News' 'What the Health?': The Supreme Court and the abortion pill

In its first abortion case since the overturning of Roe v. Wade in 2022, the Supreme Court this week looked unlikely to uphold an appeals court ruling that would dramatically restrict the availability of the abortion pill mifepristone.

28 Mar 2024

Benchmarking lifestyle medicine's effectiveness with new performance measures

An expert panel has published the first performance measures to identify remission and evaluate the effectiveness of lifestyle medicine treatments, which will allow more objective comparisons between lifestyle behavior interventions and other non-lifestyle treatments.

28 Mar 2024