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Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

The effectiveness of herbs and alternative medicines in preventing liver injury induced by anti-tuberculosis (anti-TB) drugs.

16 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Biden administration’s limit on drug industry middlemen backfires, pharmacists say

The Biden administration's first major step toward imposing limits on the pharmacy benefit managers who act as the drug industry's price negotiators is backfiring, pharmacists say.

15 Nov 2023

Existing drug that targets sleeping cells could hold the key to treating lower back pain

An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.

14 Nov 2023

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

The study in JAMA Network Open evaluates the effectiveness of simultaneously administering the Pfizer-BioNTech BNT162b2 BA.4/5 COVID-19 vaccine and seasonal influenza vaccines versus separate administration. Results suggest similar or slightly increased COVID-19 outcomes and lower influenza-related outcomes with coadministration, particularly in those aged 65 and above.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins-;a medicine used to lower "bad" cholesterol levels-; increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

UK regulator approves a diabetes drug for weight management in obese and overweight patients

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (8 November 2023) authorised via a national application route, a new indication for the diabetes medicine, Mounjaro (tirzepatide), for weight loss and weight management in adults aged 18 and over.

13 Nov 2023

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

As a founding member and former chair of the International Coalition of Medicines Regulatory Authorities (ICMRA), the Medicines and Healthcare products Regulatory Agency (MHRA) is joining global partners in celebrating ten years of strategic leadership and cooperation.

13 Nov 2023

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

In this study, researchers harnessed crowdsourcing and open science to develop new antivirals against SARS-CoV-2, focusing on its main protease, Mpro. Their approach led to the discovery of potent compounds, including one with high efficacy in cell lines and cross-reactivity against various COVID-19 variants, demonstrating the potential of collaborative and transparent drug discovery in tackling global health crises.

12 Nov 2023

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

A recent study in the journal BMC Medicine evaluates the real-world impact of combining antidepressants with statins in UK adults, revealing lower discontinuation rates but similar efficacy compared to antidepressant-only treatment.

12 Nov 2023

Developing a synthetic pathology framework: A step towards replacing animal testing

Researchers establish AnimalGAN as a reliable alternative for generating synthetic pathology data.

10 Nov 2023

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

In this groundbreaking study, researchers developed a mucosal adenoviral-vector vaccine, ChAd-SARS-CoV-2-S, which demonstrated sustained and robust immunity against a challenging Omicron variant in nonhuman primates, indicating a promising direction for durable COVID-19 protection strategies. Unlike traditional intramuscular vaccines, this mucosal vaccine elicited a comprehensive immune response, potentially paving the way for more effective and long-lasting COVID-19 vaccines.

9 Nov 2023

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

The International Vaccine Institute (IVI), an international organization with a mission to discover, develop, and deliver safe, effective, and affordable vaccines for global health, and Bio Farma, a biotechnology company based in West Java, Indonesia, announced today that Bio Farma's Bio-TCV typhoid conjugate vaccine (TCV) was licensed in Indonesia following marketing approval from Badan Pengawas Obat dan Makanan (BPOM), the national regulatory authority.

9 Nov 2023

How do sex hormones and birth control affect brain fear circuits?

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Pharmaceutical News

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Biden administration’s limit on drug industry middlemen backfires, pharmacists say

Existing drug that targets sleeping cells could hold the key to treating lower back pain

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

Revolutionizing critical care: the potential of gut microbiota therapeutics

UK regulator approves a diabetes drug for weight management in obese and overweight patients

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

Study suggests concomitant antidepressant and statin use could prevent treatment discontinuation

Developing a synthetic pathology framework: A step towards replacing animal testing

Mucosal vaccine shows lasting defense against SARS-CoV-2 Omicron in primate study

Bio Farma's Bio-TCV typhoid conjugate vaccine licensed in Indonesia following marketing approval

How do sex hormones and birth control affect brain fear circuits?

New prodrug approach enhances drug delivery to brain cells

US to cover HIV prevention drugs for older Americans to stem spread of the virus

Pharmacogenomics holds promise for personalized dementia therapies

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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