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Biden pick to lead NIH finally has her day, but still gets caught up in drug price debate

A Senate committee finally held a hearing Wednesday on President Joe Biden's pick to lead the National Institutes of Health. But the panel's chair, Sen. Bernie Sanders (I-Vt.), was focused on drug prices — an issue over which the NIH has very little control.

19 Oct 2023

Study finds strong link between genetic predisposition for blood clots and contraceptive pill use

Women with a high genetic predisposition for blood clots are six times more likely to develop a blood clot during the first two years of using contraceptive pills according to a new study from Uppsala University.

19 Oct 2023

Assessing COVID-19 vaccine effectiveness against long COVID

Researchers discuss SARS-CoV-2 vaccine effectiveness in preventing long COVID in fully vaccinated individuals.

19 Oct 2023

Study compares two widely used statins for treating patients with coronary artery disease

Two widely used statins, rosuvastatin and atorvastatin, are equally effective at preventing heart attacks, strokes and death in people with coronary artery disease.

18 Oct 2023

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Artificial intelligence has exploded in popularity and is being harnessed by some scientists to predict which molecules could treat illnesses, or to quickly screen existing medicines for new applications.

18 Oct 2023

Precision oncology therapies account for nearly half of new cancer drug approvals since 1998

Of the 198 new oncology drugs approved by the U.S. Food and Drug Administration (FDA) between 1998 and 2022, approximately 43% were precision oncology therapies, the use of which is guided by biomarker testing.

18 Oct 2023

More antibiotics not better for preventing infection after joint replacement surgery, study finds

Knee and hip replacements are increasing globally due to an aging population. In the United States, the number of patients needing a joint replacement will exceed 2.7 million in the next 7 years.

18 Oct 2023

Oral diabetes and obesity meds danuglipron and orforglipron show promise but have gastrointestinal drawbacks

New orally-administered GLP-1 receptor agonists danuglipron and orforglipron show promise in treating type 2 diabetes and obesity, according to a systematic review. While effective in glycemic control and weight reduction, these drugs come with gastrointestinal side effects that may lead to treatment discontinuation.

17 Oct 2023

Skyrocketing demand for weight-loss drugs prompts calls for informed prescribing

The study reveals a significant increase in the usage of GLP-1 receptor agonists, particularly Ozempic and Trulicity, for weight management and Type 2 diabetes in the U.S. from 2014 to 2022. Amidst rapid growth and shortages, the paper calls for evidence-based decision-making to ensure stable medication supply and effective treatment.

17 Oct 2023

Tirzepatide boosts weight loss in lifestyle intervention patients, but comes with a catch

In a groundbreaking 84-week-long study, researchers found that tirzepatide, a medication initially designed for treating type 2 diabetes, significantly bolstered weight loss in overweight and obese patients already on intensive lifestyle programs. While the drug showed promise in further reducing body weight and improving cardiometabolic factors, mild to moderate gastrointestinal side effects were the most common drawback.

16 Oct 2023

Save the environment and protect your skin while doing it – the 'cherry on top'

Researchers discover a sustainable way to repurpose tart cherry waste, harnessing its bioactive compounds for skin care applications. The study reveals that these extracts significantly protect human skin cells from oxidative stress, offering an eco-friendly solution to both food waste and skin health.

16 Oct 2023

Moffitt Cancer Center researchers identify hidden target of ROS1 inhibitor lorlatinib

Targeted cancer drugs are widely used because of their ability to inhibit specific proteins involved in cancer development with fewer side effects compared to chemotherapy drugs.

16 Oct 2023

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

The study evaluates the efficacy of a new quadrivalent mRNA influenza vaccine, finding it to be highly immunogenic and protective in a mouse model. Compared to traditional vaccines, the mRNA-based option offers advantages like reduced production time and elimination of the risk of growth-promoting mutations.

15 Oct 2023

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

The study explores the efficacy of variant-adapted COVID-19 booster vaccines, particularly against new strains like Omicron. It raises questions about the need for annual updates and the best technologies for long-term, durable immunity.

15 Oct 2023

Aureane-type sesquiterpene tetraketides hold great promise in treating IL-17A-mediated immune diseases

This new article publication from Acta Pharmaceutica Sinica B, discusses aureane-type sesquiterpene tetraketides as a novel class of immunomodulators with interleukin-17A inhibitory activity.

15 Oct 2023

New TB treatments tackle the disease without wrecking your microbiome

Researchers in a study published in The Lancet Microbe examined how various tuberculosis treatment regimens affect the respiratory microbiome. They found that certain treatments control tuberculosis effectively while minimally impacting the diversity and health of the respiratory microbiome.

15 Oct 2023

Pfizer Australia and BioNTech announce TGA approval for Omicron XBB.1.5-adapted monovalent COVID-19 vaccine

Pfizer Australia and BioNTech SE today announced that the Therapeutic Goods Administration (TGA) have authorised the companies’ XBB.1.5-adapted monovalent COVID-19 vaccine (COMIRNATY® Omicron XBB.1.5) in individuals 5 years and older.

14 Oct 2023

Opioid prescribing limits may not worsen patient experience after common surgeries

Worries that surgery patients would have a tougher recovery if their doctors had to abide by a five-day limit on opioid pain medication prescriptions didn't play out as expected, a new study finds.

13 Oct 2023

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

Moderna's updated mRNA-1273.815 COVID-19 vaccine shows promising results in reducing symptomatic cases, hospitalizations, and deaths in high-risk and older adults in Germany. The study finds the vaccine to be more cost-effective and clinically beneficial than both no vaccination and Pfizer's XBB.1.5 BNT162b2 vaccine.

12 Oct 2023

Ketamine shows complex influence on social cognition in schizophrenia, study reveals

Researchers from the University of Bonn delve into the complex relationship between ketamine and social cognition deficits in schizophrenia, revealing both promising and cautionary insights.

12 Oct 2023

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Pharmaceutical News

Biden pick to lead NIH finally has her day, but still gets caught up in drug price debate

Study finds strong link between genetic predisposition for blood clots and contraceptive pill use

Assessing COVID-19 vaccine effectiveness against long COVID

Study compares two widely used statins for treating patients with coronary artery disease

Deep learning algorithm identifies antimalarial drug as promising treatment for osteoporosis

Precision oncology therapies account for nearly half of new cancer drug approvals since 1998

More antibiotics not better for preventing infection after joint replacement surgery, study finds

Oral diabetes and obesity meds danuglipron and orforglipron show promise but have gastrointestinal drawbacks

Skyrocketing demand for weight-loss drugs prompts calls for informed prescribing

Tirzepatide boosts weight loss in lifestyle intervention patients, but comes with a catch

Save the environment and protect your skin while doing it – the 'cherry on top'

Moffitt Cancer Center researchers identify hidden target of ROS1 inhibitor lorlatinib

New mRNA flu vaccine shows promise: Faster to produce, highly effective in mice

Is it time to rethink COVID-19 boosters? New study dives into variant-specific vaccines

Aureane-type sesquiterpene tetraketides hold great promise in treating IL-17A-mediated immune diseases

New TB treatments tackle the disease without wrecking your microbiome

Pfizer Australia and BioNTech announce TGA approval for Omicron XBB.1.5-adapted monovalent COVID-19 vaccine

Opioid prescribing limits may not worsen patient experience after common surgeries

Moderna's updated COVID-19 vaccine for Autumn 2023 outperforms in cost and clinical impact

Ketamine shows complex influence on social cognition in schizophrenia, study reveals

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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