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MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (15 November 2023) extended the licence of the cystic fibrosis medicines Kaftrio (ivacaftor, tezacaftor and elexacaftor) and Kalydeco (ivacaftor) for children aged two to five years old.

20 Nov 2023

Breakthrough in tuberculosis treatment: TB-PRACTECAL trial reveals efficacy of new oral regimen

The TB-PRACTECAL clinical trial outcomes, which evaluated the efficacy and safety of oral bedaquiline.

20 Nov 2023

Norwegian study looks at which medicines best prevent migraine

Migraine is more than just a headache. Often the pain is accompanied by nausea, vomiting, light sensitivity, and sound sensitivity.

17 Nov 2023

RIT scientist earns NIH award to support research on building the next generation of drugs

Rochester Institute of Technology's Emiliano Brini, assistant professor in the School of Chemistry and Materials Science, has received an award from the National Institutes of Health (NIH) to support his research on building the next generation of drugs.

17 Nov 2023

Unraveling the immune system's response to nanoparticle drug delivery

To reduce the side effects associated with chemotherapy treatments, researchers have investigated the use of delivery systems that can take more drugs directly to the tumor. Ninh (Irene) La-Beck, Pharm.D., from the Department of Immunotherapeutics and Biotechnology at the Texas Tech University Health Sciences Center (TTUHSC) Jerry H. Hodge School of Pharmacy is one of those researchers.

17 Nov 2023

Promising new cancer therapy appears to be extremely potent against tuberculosis

A promising new cancer therapy also appears extremely potent against one of the world's most devastating infectious diseases: tuberculosis (TB).

16 Nov 2023

Study highlights variable use and rising costs of antivirals in treating pediatric influenza in the U.S.

The Pediatrics study analyzes trends in antiviral usage among U.S. children and adolescents with influenza, revealing significant variations in dispensing rates and costs, and low usage among children under six years, emphasizing the need for improved treatment strategies.

16 Nov 2023

Insulin manufacturers extend market exclusivity through additional patents, study finds

Over the last four decades, insulin manufacturers have extended their periods of market exclusivity on brand-name insulin products by employing several strategies, including filing additional patents on their products after FDA approval and obtaining many patents on delivery devices for their insulin products.

16 Nov 2023

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

Review examines nirmatrelvir and bisphosphonates in treating COVID-19, revealing their impact on SARS-CoV-2-specific adaptive immunity and potential to mitigate severe infections, highlighting the need for balanced long-term immunity management.

16 Nov 2023

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

The effectiveness of herbs and alternative medicines in preventing liver injury induced by anti-tuberculosis (anti-TB) drugs.

16 Nov 2023

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Study shows curcumin enhances antiretroviral delivery and reduces inflammation and oxidative stress in HIV, offering potential improvements in treating HIV-associated neurocognitive disorders.

16 Nov 2023

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Study reveals that senolytics can reduce aging in human brain organoids and mitigate COVID-19 neuropathology, suggesting their potential as a therapeutic strategy against brain aging and coronavirus-related neurological complications.

15 Nov 2023

Biden administration’s limit on drug industry middlemen backfires, pharmacists say

The Biden administration's first major step toward imposing limits on the pharmacy benefit managers who act as the drug industry's price negotiators is backfiring, pharmacists say.

15 Nov 2023

Existing drug that targets sleeping cells could hold the key to treating lower back pain

An existing drug that targets senescent, or sleeping cells could provide the answer to treating lower back pain, according to a new study.

14 Nov 2023

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

The study in JAMA Network Open evaluates the effectiveness of simultaneously administering the Pfizer-BioNTech BNT162b2 BA.4/5 COVID-19 vaccine and seasonal influenza vaccines versus separate administration. Results suggest similar or slightly increased COVID-19 outcomes and lower influenza-related outcomes with coadministration, particularly in those aged 65 and above.

13 Nov 2023

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

The odds of prescribing the appropriate dose of statins - a medicine used to lower "bad" cholesterol levels - increased sixfold when automated referrals were made to pharmacy services, instead of relying on traditional prescribing methods, according to researchers at the Perelman School of Medicine at the University of Pennsylvania.

13 Nov 2023

Revolutionizing critical care: the potential of gut microbiota therapeutics

The curative potential and limitations of gut microbiome-based therapeutics in critical illnesses.

13 Nov 2023

UK regulator approves a diabetes drug for weight management in obese and overweight patients

The Medicines and Healthcare products Regulatory Agency (MHRA) has today (8 November 2023) authorised via a national application route, a new indication for the diabetes medicine, Mounjaro (tirzepatide), for weight loss and weight management in adults aged 18 and over.

13 Nov 2023

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

As a founding member and former chair of the International Coalition of Medicines Regulatory Authorities (ICMRA), the Medicines and Healthcare products Regulatory Agency (MHRA) is joining global partners in celebrating ten years of strategic leadership and cooperation.

13 Nov 2023

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

In this study, researchers harnessed crowdsourcing and open science to develop new antivirals against SARS-CoV-2, focusing on its main protease, Mpro. Their approach led to the discovery of potent compounds, including one with high efficacy in cell lines and cross-reactivity against various COVID-19 variants, demonstrating the potential of collaborative and transparent drug discovery in tackling global health crises.

12 Nov 2023

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Pharmaceutical News

MHRA extends the license of two cystic fibrosis drugs for children aged two to five years old

Breakthrough in tuberculosis treatment: TB-PRACTECAL trial reveals efficacy of new oral regimen

Norwegian study looks at which medicines best prevent migraine

RIT scientist earns NIH award to support research on building the next generation of drugs

Unraveling the immune system's response to nanoparticle drug delivery

Promising new cancer therapy appears to be extremely potent against tuberculosis

Study highlights variable use and rising costs of antivirals in treating pediatric influenza in the U.S.

Insulin manufacturers extend market exclusivity through additional patents, study finds

Exploring the dual role of nirmatrelvir and bisphosphonates in COVID-19 treatment and immunity

New study reveals turmeric and Tinospora Cordifolia reduce liver injury risk in TB patients

Curcumin boosts brain delivery of HIV drug, curbing inflammation and oxidative stress

Senolytics show promise in combating brain aging and COVID-19 neuropathology

Biden administration’s limit on drug industry middlemen backfires, pharmacists say

Existing drug that targets sleeping cells could hold the key to treating lower back pain

Study reveals coadministered COVID-19 and flu vaccines effective, especially in seniors

Automated referrals to pharmacy services dramatically increase appropriate statin prescription rates

Revolutionizing critical care: the potential of gut microbiota therapeutics

UK regulator approves a diabetes drug for weight management in obese and overweight patients

MHRA and partners celebrate 10th anniversary of the International Coalition of Medicines Regulatory Authorities

Open-science triumph: Crowdsourced initiative yields potent SARS-CoV-2 antivirals

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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