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Many cancer drugs approved without clear evidence of benefit, study shows

New cancer drugs are being launched at a rapid pace, before their long-term effectiveness for patients can be evaluated.

15 Aug 2023

Epigenetic manipulation may improve breast cancer treatment responses

Researchers explore the possibility of increasing TROP2 ADC activity by enhancing the expression of TROP2 on cancer cells.

15 Aug 2023

Novel multi-epitope subunit vaccine induces robust immune response against Epstein-Barr virus

Scientists have developed a lymph node-targeted multi-epitope subunit vaccine that induces strong humoral and cellular immune responses against EBV in mice.

14 Aug 2023

$Study suggests Vitamin D prescription lowers hip fracture incidence$

Study suggests Vitamin D prescription lowers hip fracture incidence

Researchers examined the relationship between vitamin D supplementation and osteoporosis-related fracture incidence.

14 Aug 2023

New Alzheimer’s drug raises hopes — along with questions

The FDA has approved Leqembi, the first disease-modifying treatment for early-stage Alzheimer's and a precursor condition, mild cognitive impairment.

11 Aug 2023

Illustrating the safety of a new drug treatment designed for spinal cord injury

New orally available drug for spinal cord injury found to be safe and tolerable in healthy participants.

11 Aug 2023

A third dose boosted cross-protection against SARS-CoV-2 viral variants, finds study

Transplant recipients must take life-long immunosuppressive medications to prevent rejection, but these drugs can compromise the effectiveness of vaccines.

11 Aug 2023

Study explores the use of existing medicines to revolutionize cancer treatment

In a recent study published in the journal of Genes & Diseases, Research team led by Lu explores the potential for the use of FDA-approved hypertension and EMA-approved cough medicines to revolutionize cancer treatment.

10 Aug 2023

$Patients prescribed corticosteroids less likely to receive fracture preventive care$

Patients prescribed corticosteroids less likely to receive fracture preventive care

Prolonged use of corticosteroids, such as prednisolone, has been shown to cause osteoporosis and therefore increases the risk of breaking a bone.

10 Aug 2023

Revolutionizing type 2 diabetes treatment: personalized approach shows promise in matching patients with optimal glucose-lowering therapies

A personalized therapy selection algorithm for two diabetes type 2 (T2D) treatment drug classes.

10 Aug 2023

Dementia risk may increase with long-term use of acid reflux drugs

People who take acid reflux medications called proton pump inhibitors for four-and-a-half years or more may have a higher risk of dementia compared to people who do not take these medications, according to new research published in the August 9, 2023, online issue of Neurology®, the medical journal of the American Academy of Neurology.

9 Aug 2023

Researchers develop antibody drugs from tobacco plants for cancer treatment

For the first time in Thailand, lecturers at Chulalongkorn University's Faculty of Pharmaceutical Sciences have successfully developed antibody from tobacco plants with inhibitory effects on the growth of cancer cells in laboratory animals.

9 Aug 2023

The immune-modulatory effect of lenvatinib investigated in new study

Researchers explore the effect of lenvatinib treatment on patients with advanced thyroid cancer.

9 Aug 2023

New guidance provides clear advice to reduce medication errors in anesthesia care

New guidance published in Anaesthesia (the journal of the Association of Anaesthetists) provides clear advice to reduce avoidable errors on all steps of the pathway involving injectable medications used routinely in anesthesia care.

8 Aug 2023

Seeking Medicare coverage for weight loss drugs, pharma giant courts Black influencers

Pharmaceutical giant Novo Nordisk has turned to influential Black Americans in pursuit of what would be a lucrative victory: having Medicare cover a new class of weight loss drugs, including the company's highly sought Wegovy, which can cost patients more than $1,000 a month.

8 Aug 2023

University of Michigan and Zingerman's launch pilot program to train employees in use of naloxone

In an effort to expand the use of lifesaving opioid overdose reversal medication, the University of Michigan and Ann Arbor’s Zingerman’s Community of Businesses are launching a restaurant-based pilot program in Michigan to train employees in the use and administration of naloxone.

7 Aug 2023

Exploring the safety of COVID-19 mRNA vaccines in the elderly

Researchers evaluate the risks of possible adverse events following COVID-19 mRNA vaccination in the elderly.

7 Aug 2023

Survey: Americans want weight loss drugs despite high cost

Many Americans really want to lose weight — and a new poll shows nearly half of adults would be interested in taking a prescription drug to help them do so.

5 Aug 2023

Penn State researchers develop new method for creating cyclopropanes

Chemical structures called cyclopropanes can increase the potency and fine-tune the properties of many drugs, but traditional methods to create this structure only work with certain molecules and require highly reactive-;potentially explosive-;ingredients. Now, a team of researchers from Penn State has identified and demonstrated a safe, efficient and practical way to create cyclopropanes on a wide variety of molecules using a previously undescribed chemical process.

4 Aug 2023

New study provides promising results for metformin in periodontitis

Periodontitis, a prevalent global health concern, results in the gradual destruction of tooth-supporting tissues and is often exacerbated by oxidative stress conditions and bacterial changes. Current treatment methodologies include mechanical debridement, anti-inflammatory drugs, and regenerative surgery.

4 Aug 2023