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COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

A study published in the journal Frontiers in Immunology describes that the third booster dose of coronavirus disease 2019 (COVID-19) effectively induces an immune response against immunologically more fit variants of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). However, the immunity induced by the booster vaccination is transient and gradually declines over time.

15 Nov 2022

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

In a recent study published in the journal npj Vaccines, researchers in China designed, produced, and evaluated the neutralization efficacy of a recombinant coronavirus disease 2019 (COVID-19) vaccine containing four hot-spot substitution mutations based on a prefusion-stabilized severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) spike protein (S) trimer.

15 Nov 2022

Medicare plan finder likely won’t note new $35 cap on out-of-pocket insulin costs

A big cut in prescription drug prices for some Medicare beneficiaries kicks in next year, but finding those savings isn't easy.

15 Nov 2022

Moderna's bivalent boosters trigger strong antibody response against latest subvariants

Moderna reports the efficacy of a bivalent COVID-19 vaccine booster dose.

14 Nov 2022

A novel mRNA-based vaccine candidate against the rabies virus

Scientists have developed a novel mRNA-based vaccine candidate against the rabies virus. The vaccine induces a strong antibody response and exhibits high protective efficacy against lethal rabies infection in mice and dogs. A full report about the vaccine has been published in the Virology Journal.

14 Nov 2022

New fentanyl vaccine could prevent deadly opioid from entering the brain

A research team led by the University of Houston has developed a vaccine targeting the dangerous synthetic opioid fentanyl that could block its ability to enter the brain, thus eliminating the drug's "high."

14 Nov 2022

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

A recent study posted to medRxiv* examined adverse reactions after administration of a bivalent BNT162b2 coronavirus disease 2019 (COVID-19) vaccine booster.

13 Nov 2022

Researchers trace the origin of Japan’s traditional Kampo medicines

Traditional Chinese medicine (TCM) has been around for centuries. With a history of almost 3000 years dating back to the early Zhou Dynasty, it has been incorporated into China's present medical system.

11 Nov 2022

Fentanyl in high school: A Texas community grapples with the reach of the deadly opioid

The hallways of Lehman High School looked like any other on a recent fall day. Its 2,100 students talked and laughed as they hurried to their next classes, moving past walls covered with flyers that advertised homecoming events, clubs, and football games.

10 Nov 2022

Biodegradable transport nanoparticle can make anti-inflammatory drug more effective and less toxic

A team from UNIGE and LMU developed a transport nanoparticle to make an anti-inflammatory drug much more effective and less toxic.

9 Nov 2022

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

In a recent study posted to the Research Square* preprint server and under review at the Nature Portfolio journal, researchers reported activation and maturation of antigen-presenting cells (APCs) by lipid nanoparticles (LNPs).

9 Nov 2022

Expanding the therapeutic toolbox for mood disorders with psychoactive drugs

There is a need for new, effective treatments for mental illnesses like depression and anxiety. Researchers are expanding the field's therapeutic toolbox by investigating the antidepressant and anxiolytic properties of drugs such as psilocybin and cannabis.

9 Nov 2022

Updated CDC guidelines for prescribing opioids

The United States Centers CDC updated their clinical practice guidelines for opioid prescription in pain management.

8 Nov 2022

Terasaki Innovation Summit to focus on improving technological, entrepreneurial translation of personalized medicines

The Terasaki Institute for Biomedical Innovation (TIBI) will be hosting the Terasaki Innovation Summit on March 8-10, 2023, at the UCLA Meyer & Renee Luskin Center in Los Angeles.

8 Nov 2022

Defense department health plan cuts its pharmacy network by nearly 15,000 outlets

Doris Spatz takes a once-a-day pill, Kisqali, to keep her metastatic breast cancer in check. As a patient in the Defense Department health system, she can fill routine prescriptions at a military pharmacy without a copay but also has the option of using a regular pharmacy through Tricare, the Defense Department's private health care program.

8 Nov 2022

Rosuvastatin vastly superior to six common heart health supplements

Six widely used dietary supplements often advertised to promote heart health are actually ineffective at lowering cholesterol levels.

7 Nov 2022

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

In a recent study posted to the medRxiv* preprint server, researchers in Canada evaluated nirmatrelvir and ritonavir (Paxlovid) effectiveness against severe coronavirus disease 2019 (COVID-19) during the dominance of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Omicron variant of concern (VOC) and Omicron sub-VOCs in Canada.

7 Nov 2022

Paxlovid antiviral therapy reduces risk of long COVID

In a recent study posted to the medRxiv* server, researchers in Saint Louis, Missouri, examined whether nirmatrelvir treatment reduced the risk of long COVID, the disease encompassing the post-acute sequelae of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) [PASC].

7 Nov 2022

Two heart failure therapies prove to be nearly identical in reducing death

In a head-to-head comparison of two so-called 'water pills' that keep fluid from building up in patients with heart failure, the therapies proved nearly identical in reducing deaths, according to a large study led by Duke Health researchers.

6 Nov 2022

Weekly weight loss drug reduces BMI in teens

Researchers report that a weekly dose of semaglutide led to a significant BMI reduction in adolescents.

3 Nov 2022

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Pharmaceutical News

COVID-19 mRNA boosters induce robust but non-durable immune response in the elderly

Development of a potent, broadly protective vaccine against all SARS-CoV-2 variants

Medicare plan finder likely won’t note new $35 cap on out-of-pocket insulin costs

Moderna's bivalent boosters trigger strong antibody response against latest subvariants

A novel mRNA-based vaccine candidate against the rabies virus

New fentanyl vaccine could prevent deadly opioid from entering the brain

More adverse reactions following bivalent COVID-19 mRNA booster vaccine

Researchers trace the origin of Japan’s traditional Kampo medicines

Fentanyl in high school: A Texas community grapples with the reach of the deadly opioid

Biodegradable transport nanoparticle can make anti-inflammatory drug more effective and less toxic

Empty lipid nanoparticles trigger maturation and activation of antigen-presenting cells

Expanding the therapeutic toolbox for mood disorders with psychoactive drugs

Updated CDC guidelines for prescribing opioids

Terasaki Innovation Summit to focus on improving technological, entrepreneurial translation of personalized medicines

Defense department health plan cuts its pharmacy network by nearly 15,000 outlets

Rosuvastatin vastly superior to six common heart health supplements

Study shows consistent efficacy of Paxlovid regardless of age, number of vaccinations, comorbidities

Paxlovid antiviral therapy reduces risk of long COVID

Two heart failure therapies prove to be nearly identical in reducing death

Weekly weight loss drug reduces BMI in teens

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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