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Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Researchers investigate whether the SARS-CoV-2 Omicron variant is more likely to infect vaccinated individuals than the SARS-CoV-2 Delta variant.

30 Jan 2022

Treating COVID with antibiotics could be a much simpler way of making people better

A recent study conducted in an Egyptian hospital showed that treating moderate-to-severe COVID patients with either one of two antibiotics (ceftazidime or cefepime, in combination with a steroid) resulted in similar recovery times compared to patients given standard treatment.

29 Jan 2022

New study offers valuable information on ocular drug metabolism and pharmacokinetics

Severe visual illnesses are increasing in our society, and effective treatments are missing for diseases as age-related macular degeneration, diabetic retinopathy, and glaucoma. Both industry and academia are highly interested to advance ocular drug discovery and development.

29 Jan 2022

Hospitalized COVID-19 patients more likely to experience heavy bleeding when prescribed full-dose blood thinners

Patients with COVID-19 in the intensive care unit (ICU) prescribed full-dose blood thinners are significantly more likely to experience heavy bleeding than patients prescribed a smaller yet equally effective dose, according to a recent University at Buffalo-led study.

28 Jan 2022

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

Researchers compare the humoral immune response in adolescents and adults after being completely immunized with the Pfizer BNT162b2 vaccine.

28 Jan 2022

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Researchers look to better understand the molecular basis of E406W-mediated escape from the REGEN-COV cocktail and cilgavimab.

28 Jan 2022

Psychedelic analogs show antidepressant-like activity in mice without causing hallucination

Analogs of drugs like psilocybin and LSD show antidepressant-like activity in mice without causing hallucination, researchers report.

27 Jan 2022

Aceto consolidates acquisition of six manufacturers, strengthening its unique hybrid model that provides major supply chain benefits to customers

Aceto, a leading global provider of specialty materials for life sciences and advanced technology end markets, today reported it has consolidated and integrated its six manufacturing-related acquisitions to achieve a hybrid manufacturing/distribution model providing key benefits to its customers in high-growth end markets including pharmaceuticals, biopharmaceuticals, vaccines, nutraceuticals, agriculture, cosmetics and specialty chemicals.

27 Jan 2022

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

In the recently published study in The Lancet, first-authored by Dr. Sue Ann Costa Clemens from the University of Oxford in the United Kingdom and the University of Siena in Italy, a comprehensive analysis has been pursued on the immunogenicity and safety of both homologous and heterologous boosting after receiving the inactivated vaccine CoronaVac.

26 Jan 2022

Breast cancer drug shows promise in treating young infants with PIK3CA-related overgrowth spectrum

PIK3CA-related overgrowth spectrum (PROS) is a group of rare, incurable disorders caused by mutations in the PIK3CA gene that result in the malformation and overgrowth of various parts of the body.

26 Jan 2022

Ancillary costs associated with use of Alzheimer's drug aducanumab could add pressure on Medicare

A UCLA-led cost analysis of the controversial new Alzheimer's disease drug aducanumab shows that ancillary care services, such as additional MRIs and neurologist visits to monitor the potential brain swelling and bleeding associated with the medication, account for nearly 20% of total Medicare costs related to the drug, or $6,564 per patient per year.

25 Jan 2022

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

A new study assesses the effectiveness of two and three doses of the BNT162b2 vaccine against Omicron-related hospitalizations.

25 Jan 2022

Pharmacies are turning away immunocompromised patients seeking 4th covid shot

Patients with weakened immune systems — who are at high risk from covid-19 — say pharmacies are turning them away when they seek additional vaccine doses recommended by federal health officials.

25 Jan 2022

I write about America’s absurd health care system. Then I got caught up in it.

I got a hurried voicemail from my pharmacist in Wisconsin the day before Thanksgiving letting me know my insurance was refusing to cover my insulin.

25 Jan 2022

Lower risk of vaccine-breakthrough infections for mRNA-1273 recipients

Recently, a team of researchers examined breakthrough infections, hospitalizations, and mortality rates in double-dose messenger RNA (mRNA) vaccine recipients in a research letter published in the Journal of American Medical Association (JAMA).

24 Jan 2022

Most DMARDs not linked with the risk of Parkinson's disease in people with rheumatoid arthritis

The autoimmune disorder rheumatoid arthritis has been associated with a lower risk of Parkinson's disease (PD) in previous studies, with antirheumatic drugs as one possible explanatio

24 Jan 2022

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

In a recent study posted to the bioRxiv* preprint server, researchers test three severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) antivirals authorized for emergency use by the United States Food and Drug Administration (FDA) for their in vitro potency against several SARS-CoV-2 variants, including the currently dominant Omicron train.

23 Jan 2022

Robust BNT162b2 vaccine-induced B and T-cell immunity against early SARS-CoV-2 variants

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Pharmaceutical News

Escape from vaccine-induced immunity likely contributed to rapid rise of SARS-CoV-2 Omicron

Treating COVID with antibiotics could be a much simpler way of making people better

New study offers valuable information on ocular drug metabolism and pharmacokinetics

Hospitalized COVID-19 patients more likely to experience heavy bleeding when prescribed full-dose blood thinners

Reduced neutralization against Omicron variant in fully immunized adolescents with BNT162b2 vaccine

E406W mutation on SARS-CoV-2 RBD escapes monoclonal antibody cocktail-mediated neutralization

Psychedelic analogs show antidepressant-like activity in mice without causing hallucination

Aceto consolidates acquisition of six manufacturers, strengthening its unique hybrid model that provides major supply chain benefits to customers

Recipients of inactivated COVID-19 vaccine (CoronaVac) can be successfully boosted with different vaccines

Breast cancer drug shows promise in treating young infants with PIK3CA-related overgrowth spectrum

Ancillary costs associated with use of Alzheimer's drug aducanumab could add pressure on Medicare

Third dose of BNT162b2 vaccine protects against Omicron hospitalizations

Pharmacies are turning away immunocompromised patients seeking 4th covid shot

I write about America’s absurd health care system. Then I got caught up in it.

Lower risk of vaccine-breakthrough infections for mRNA-1273 recipients

Most DMARDs not linked with the risk of Parkinson's disease in people with rheumatoid arthritis

Nirmatrelvir, Molnupiravir, and Remdesivir hold-up against SARS-CoV-2 Omicron variant in vitro

Robust BNT162b2 vaccine-induced B and T-cell immunity against early SARS-CoV-2 variants

CoronaVac provides herd immunity in region of the Colombian Amazon

Paxlovid provides a glimpse into the future against SARS-CoV-2

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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