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Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Direct oral anti-coagulant (anti-clotting) (DOAC) medications that target a single clotting factor work just as well to prevent future clots as the older, less-specific medication warfarin.

11 Feb 2022

Newer clot-busting drug may lengthen the window for additional stroke treatment to 24 hours

If patients with clot-caused strokes obtain medical care more than 4½ hours after their symptoms are noticed, it is too late to receive the standard clot-busting medication alteplase.

11 Feb 2022

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

A study published on the bioRxiv* preprint server evaluates molnupiravir against a panel of relevant VOCs using three efficacy models: primary human airway epithelium organoids, a ferret model of upper respiratory disease, and a Roborovski dwarf hamster model for severe COVID-19.

9 Feb 2022

Researchers identify a potent new combination of antiviral drugs to combat SARS-CoV-2

The recent success of Paxlovid has encouraged researchers to develop new anti-covid drugs. With this in mind, scientists from the University of Pennsylvania have been investigating a new synergistic treatment. Their research is released early as an unedited version of the manuscript to be published in the journal Nature.

9 Feb 2022

UCI case report: Antihistamines may provide relief for people suffering from long COVID-19 symptoms

Antihistamines may provide relief for the millions of people suffering from the painful, debilitating symptoms of long COVID-19 that impair daily functioning.

9 Feb 2022

Study highlights benefit of mRNA boosters for SARS-CoV-2 following different initial vaccine types

A study by researchers from the United Kingdom finds no difference in the protection offered by mRNA vaccine boosters against the severe acute respiratory syndrome coronavirus 2 (SARS‑CoV‑2) when comparing those that have received BioNTech/Pfizer vaccine as a primary course to those that have received Oxford/AstraZeneca.

8 Feb 2022

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

In a recent research paper published in the journal Infection, the scientists estimated the transmission and disease severity associated with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta variant and the effectiveness of the current coronavirus disease 2019 (COVID-19) vaccines against the same by conducting a literature review. Further, a meta-analysis was conducted to obtain a numeric estimate of the vaccine effectiveness against the Delta variant.

7 Feb 2022

"Drug checking" programs have unexpected benefits, study finds

A recent study has found that so-called "drug checking" programs have unexpected benefits, allowing public health programs to reach and work with people who use drugs who would otherwise not access services such as HIV testing.

7 Feb 2022

Paracetamol use increases blood pressure, study shows

Long-term paracetamol use could increase the risk of heart disease and strokes in people with high blood pressure, a study suggests.

7 Feb 2022

Booster dose of Pfizer-BioNTech COVID vaccine protects elderly against Omicron

Researchers discuss the impact of mRNA booster immunization on the neutralizing activity against the SARS-CoV-2 Omicron variant in the elderly.

6 Feb 2022

Nuvaxovid COVID-19 vaccine given regulatory approval By MHRA

Nuvaxovid, the COVID-19 vaccine developed by Novavax, has today been given regulatory approval by the Medicines and Healthcare products Regulatory Agency (MHRA).

3 Feb 2022

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Researchers evaluate the neutralization potential of sera samples from subjects boosted with the Covaxin against the SARS-CoV-2 Omicron variant.

2 Feb 2022

Developing post-vaccination SARS-CoV-2 standard reference sera

A new study reports the generation of reference sera reagents that were obtained from subjects vaccinated with one of four COVID-19 vaccines.

1 Feb 2022

High levels of neutralizing antibodies against Omicron after BNT162b2 booster vaccination

Researchers analyze the neutralizing antibody levels against SARS-CoV-2 VOCs in individuals after receiving their second and third doses.

1 Feb 2022

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

A new study has assessed the antibody responses to the mRNA-1273 Moderna vaccine over time.

31 Jan 2022

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Researchers from Moderna, the developers of one key vaccine, have been investigating its ability to protect against the Omicron variant.

31 Jan 2022

Study finds limited evidence for IL-1 blockers in treating COVID-19

Researchers assess the effectiveness and safety outcomes of interleukin-1 blocking agents in the treatment of COVID-19.

31 Jan 2022

Children and adolescents respond as well or better than adults to mRNA-1273 COVID vaccination

A recent study assesses the neutralization efficacy of the mRNA-1273 vaccine against the SARS-CoV-2 Omicron variant in children, adolescents, and adults.

30 Jan 2022

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

Researchers screen kidney transplant recipients to evaluate their serological responses following immunization with three doses of the COVID-19 vaccine.

30 Jan 2022

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Researchers study the interaction between immunity to endemic coronaviruses and SARS-CoV-2.

30 Jan 2022

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Pharmaceutical News

Direct oral anti-coagulants less likely to result in major bleeding after rare, fatal stroke

Newer clot-busting drug may lengthen the window for additional stroke treatment to 24 hours

Study tests efficacy of molnupiravir against SARS-CoV-2 VOCs in various animal models

Researchers identify a potent new combination of antiviral drugs to combat SARS-CoV-2

UCI case report: Antihistamines may provide relief for people suffering from long COVID-19 symptoms

Study highlights benefit of mRNA boosters for SARS-CoV-2 following different initial vaccine types

SARS-CoV-2 Delta variant's effect on COVID-19 vaccine efficacy

"Drug checking" programs have unexpected benefits, study finds

Paracetamol use increases blood pressure, study shows

Booster dose of Pfizer-BioNTech COVID vaccine protects elderly against Omicron

Nuvaxovid COVID-19 vaccine given regulatory approval By MHRA

Booster dose of Covaxin vaccine candidate neutralizes Omicron and Delta variants

Developing post-vaccination SARS-CoV-2 standard reference sera

High levels of neutralizing antibodies against Omicron after BNT162b2 booster vaccination

Study assesses anti-SARS-CoV-2 antibody response to mRNA-1273 vaccination over time

Preliminary study assesses durability of NAb titers against Omicron after mRNA-1273 booster

Study finds limited evidence for IL-1 blockers in treating COVID-19

Children and adolescents respond as well or better than adults to mRNA-1273 COVID vaccination

Study shows homologous COVID boosters better than heterologous in most kidney transplant recipients

COVID-19 vaccines elicit cross-reactive antibodies against endemic coronaviruses

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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