CRISPR News and Research

Latest CRISPR News and Research

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

In pediatric and young adult patients with acute lymphoblastic leukemia (ALL) treated with tisagenlecleucel (Kymriah), DNA sequencing-based detection of residual disease between three and 12 months accurately identified all patients who would eventually relapse, while other methods were less predictive.

1 Dec 2021

Novel anti-inflammatory drug target identified by CRISPR

In this interview, News-Medical speaks to Dr. Jeffrey Rathmell about his recent research into how metabolic pathways impact immune function.

1 Dec 2021

New method can precisely, rapidly correct genetic alterations in patient cells

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

Immunotherapies have shown striking clinical benefit in the treatment of many cancers, especially when used in combination with chemotherapy.

30 Nov 2021

New method helps correct genetic alterations in the cultured patient cells rapidly

Researchers in the University of Helsinki and University Hospital Helsinki have developed a method to precisely and rapidly correct genetic alterations in the cultured patient cells.

30 Nov 2021

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

In a recent study, published on the bioRxiv* preprint server, researchers identified human LRRC15 as an inhibitory receptor for SARS-CoV-2 entry, which directly binds to the receptor-binding domain (RBD) of the spike protein with a moderate affinity and inhibits spike-mediated entry.

29 Nov 2021

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

A recent research paper by scientists from Denmark reveals that circulating plasmacytoid dendritic cells may be a potential therapeutic target to maintain desired levels of an antiviral compound known as interferon, allowing for the mitigation of coronavirus disease (COVID-19) severity. The study is currently available on the bioRxiv* preprint server while it undergoes peer review.

28 Nov 2021

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

LMU immunologists have discovered how mutations in Roquin-1 trigger autoimmunity, but can also improve the body's fight against cancer cells.

25 Nov 2021

Paper-based innovations for COVID-19 diagnosis

A review discusses paper-based devices and platforms targeting SARS-CoV-2 for low-cost PoC diagnosis and serological antibody testing.

22 Nov 2021

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

Turkish researchers discuss their rapid electrochemical biosensing platform to detect the SARS-CoV-2 spike antibody.

22 Nov 2021

New insights on the link between CRISPR, p53 gene and mutated cancer cells

A protein that protects cells from DNA damage, p53, is activated during gene editing using the CRISPR technique.

18 Nov 2021

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Researchers recently conducted a study to identify host factors affecting cellular interactions of the SARS-CoV-2 spike protein.

16 Nov 2021

Study highlights the need for caution while using CRISPR-based gene therapies

A comprehensive study - conducted by researchers at Sanford Burnham Prebys, the National Cancer Institute (NCI) and other groups - has shown that gene editing, specifically gene knockout (KO), with CRISPR -Cas9 can favor cells with mutated forms of genes linked to cancer.

11 Nov 2021

New study offers genetic insight into why we look the way we do

Which genes control the defining features that make us look as we do? And how do they make it happen?

11 Nov 2021

New epigenetic editing technique may advance the treatment of many diseases

Type 1 diabetes, rheumatoid arthritis, and cancer are just some of the disorders associated with specific genes not "turning on" and "turning off" as they should.

9 Nov 2021

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

Blending experts from molecular genetics, chemistry and health sciences, researchers at the University of California San Diego have created a rapid diagnostic technology that detects SARS-CoV-2, the coronavirus that causes COVID-19.

6 Nov 2021

Experts gain insights into pathomechanisms of dilated cardiomyopathy

Titin is a "titanically large" protein – the largest in the human body – which enables elastic movements of our muscles, including the heart.

6 Nov 2021

Development of SARS-CoV-2 detection platform using surface-enhanced Raman spectroscopy

Researchers have tried to develop an innovative platform for ultrasensitive and rapid detection of SARS-CoV-2 by exploiting a variation of Raman Spectroscopy.

4 Nov 2021

Cas13 shines a light on SARS-CoV-2 variants

Now, a new study published on the medRxiv* preprint server describes and benchmarks SHINEv2, a Cas13-based nucleic acid diagnostic for SARS-CoV-2 detection. SHINEv2 combines temperature sample processing and lyophilized reagents to simplify the test procedure and assay distribution immensely.

4 Nov 2021

The role of CRISPR in viral diagnostics

A comprehensive review explains in depth how CRISPR can be utilized as a reliable tool to investigate the viral life cycles.

29 Oct 2021

CRISPR News and Research

Latest CRISPR News and Research

DNA sequencing of residual disease accurately identifies leukemia patients who would relapse

Novel anti-inflammatory drug target identified by CRISPR

New method can precisely, rapidly correct genetic alterations in patient cells

Study identifies two genes that play key role in protecting ovarian cancer from the immune system

New method helps correct genetic alterations in the cultured patient cells rapidly

Human LRRC15 protein is an inhibitory receptor for SARS-CoV-2 spike-mediated entry

Study shows plasmacytoid dendritic cells may be a viable target for protection against SARS-CoV-2

LMU immunologists reveal how Roquin-1 controls the activity of immune cells

Paper-based innovations for COVID-19 diagnosis

Detection of SARS-CoV-2 spike antibody using electrochemical biosensing based on hydrogen bonding

New insights on the link between CRISPR, p53 gene and mutated cancer cells

Discovery of new receptor that interacts with SARS-CoV-2 spike, suppresses infection

Study highlights the need for caution while using CRISPR-based gene therapies

New study offers genetic insight into why we look the way we do

New epigenetic editing technique may advance the treatment of many diseases

Scientists create a rapid diagnostic technology to detect SARS-CoV-2

Experts gain insights into pathomechanisms of dilated cardiomyopathy

Development of SARS-CoV-2 detection platform using surface-enhanced Raman spectroscopy

Cas13 shines a light on SARS-CoV-2 variants

The role of CRISPR in viral diagnostics

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