CRISPR News and Research

Latest CRISPR News and Research

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

A recent study shows how a novel and integrated lab-on-a-chip platform can represent a rapid, affordable, and exact molecular diagnostic tool for detecting severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2). The paper is currently available for free on the medRxiv* preprint server while it undergoes peer review.

9 Jan 2022

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

When a patient receives a kidney transplant, doctors carefully monitor them for signs of rejection in several ways, including biopsy. However, this procedure is invasive and can only detect issues at a late stage.

5 Jan 2022

Unique nanoparticle can deliver genome editing technology to endothelial cells

The lab of Youyang Zhao, PhD, from Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago developed a unique nanoparticle to deliver genome editing technology, including CRISPR/Cas9, to endothelial cells, which are cells that line blood vessel walls.

4 Jan 2022

SARS-CoV-2 differs from other betacoronaviruses in a key IRE1α/XBP1 pathway

SARS-CoV-2 differs from other viruses in the beta coronavirus family in the activation of a key pathway associated with endoplasmic reticulum stress.

3 Jan 2022

Study casts light on how to combine antibiotics and phage therapy to fight bacterial infection

New research has moved a step closer to harnessing viruses to fight bacterial infection, reducing the threat of antibiotic resistance.

20 Dec 2021

CRISPR-based microfluidic platform detects respiratory viruses and SARS-CoV-2 variants

Researchers in the US have developed a novel multiplexed diagnostic platform based on CRISPR-based approaches and microfluidics - enabling robust and simultaneous surveillance of multiple viruses and viral variants. Currently, the paper is available on the medRxiv* preprint server pending peer review.

19 Dec 2021

Services to accelerate genome editing research

AMSBIO has expanded its range of custom gene editing services to complement its extensive portfolio of off-the-shelf CRISPR/Cas9 products.

From AMS Biotechnology 17 Dec 2021

Eating before saliva collection may interfere with detection of SARS-CoV-2

A new study, published on the medRxiv* preprint server, has aimed to determine if children's diet impacts the detection of SARS-CoV-2 virus in saliva. Scientists performed diagnostic tests to detect this virus using real-time self-collected specimens provided by five healthy children. The samples were collected before and after eating selected foods. The specific time of collection of samples after eating were 0 minutes, 20 minutes, and 60 minutes after eating.

15 Dec 2021

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

A recent study recently demonstrates the endosomal transport of nanoparticle-based formulations for the effective delivery of mRNA-based therapeutics.

14 Dec 2021

Flawed genetic switches could be at the origin of malformations or developmental diseases

Embryonic development follows delicate stages: for everything to go well, many genes must coordinate their activity according to a very meticulous scheme and tempo. This precision mechanism sometimes fails, leading to more or less disabling malformations.

14 Dec 2021

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

A recent review in the journal Life provided a detailed description of CRISPR-Cas-based diagnostic techniques to identify severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, but also emphasized the potential use of this technology towards developing effective molecular diagnostic platforms for any future pandemic.

13 Dec 2021

CRISPR/Cas9 gene editing enables sonodynamic therapy to effectively shrink tumors

Sonodynamic therapy uses ultrasound in combination with drugs to release harmful reactive oxygen species (ROS) at the site of a tumor.

8 Dec 2021

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

A recent review looks at the molecular design of pH-sensitive cationic lipids and their applications for various tissues and cell types.

7 Dec 2021

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

Scientists develop an improved biosensor with Cas12a-based CRISPR on-site rapid detection system and discuss its ability to detect SARS-CoV-2 VOCs.

7 Dec 2021

Research offers pathway for manufacturing cell cultured meat and breeding enhanced livestock

Scientists have for the first time obtained stem cells from livestock that grow under chemically defined conditions, paving the way for manufacturing cell cultured meat and breeding enhanced livestock.

7 Dec 2021

Researchers use gene-editing to create single sex mice litters

Scientists at the Francis Crick Institute, in collaboration with University of Kent, have used gene editing technology to create female-only and male-only mice litters with 100% efficiency.

6 Dec 2021

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

This work has emphasized the clinical and translational potential of paper-based biosensors.

6 Dec 2021

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

Each year The Scientist seeks to highlight the latest and greatest tools, technologies, and techniques to hit the life science landscape.

From Resolve Biosciences 6 Dec 2021

CRISPR-based DETECTR® assay for faster SARS-CoV-2 surveillance

Researchers from the USA discuss the development and validation of CRISPR-Cas12-based COVID-19 variant DETECTR® assay for the detection of SARS-CoV-2.

3 Dec 2021

Researchers introduce new method for observing cell interactions

Researchers created a system that allows scientists to ‘log’ a cell’s reactions to external stimuli within the cell’s genetic material.

2 Dec 2021

CRISPR News and Research

Latest CRISPR News and Research

New lab-on-a-chip platform for detecting SARS-CoV-2 in resource-limited settings

New CRISPR-based assay can non-invasively detect a biomarker of acute kidney rejection in urine

Unique nanoparticle can deliver genome editing technology to endothelial cells

SARS-CoV-2 differs from other betacoronaviruses in a key IRE1α/XBP1 pathway

Study casts light on how to combine antibiotics and phage therapy to fight bacterial infection

CRISPR-based microfluidic platform detects respiratory viruses and SARS-CoV-2 variants

Services to accelerate genome editing research

Eating before saliva collection may interfere with detection of SARS-CoV-2

Recycling tubular endosomes are associated with effective delivery of mRNA-based therapeutics, study finds

Flawed genetic switches could be at the origin of malformations or developmental diseases

CRISPR-Cas enzyme-based diagnostics to detect SARS-CoV-2 infection

CRISPR/Cas9 gene editing enables sonodynamic therapy to effectively shrink tumors

An assessment of pH-sensitive cationic lipid nanoparticles for drug delivery

Cas12a-based bio-sensor for detecting SARS-CoV-2 mutations

Research offers pathway for manufacturing cell cultured meat and breeding enhanced livestock

Researchers use gene-editing to create single sex mice litters

Colorimetric detection of SARS-CoV-2 viral RNA by an in vitro transcription/translation assay

Announcing the Winners of The Scientist’s Top 10 Innovations of 2021

CRISPR-based DETECTR® assay for faster SARS-CoV-2 surveillance

Researchers introduce new method for observing cell interactions

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

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