CRISPR News and Research

Latest CRISPR News and Research

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

In a methodologically trailblazing paper published in the journal Nature Genetics, a team of Belgian scientists uncovered an assembly of coronavirus host factors that may be exploited to develop drugs against the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), but also potentially forthcoming zoonotic coronaviruses.

14 Mar 2021

Optimizing The Genome Editing Workflow With Microfluidic Technology

A recent grant collaboration, funded by Innovate UK, between Sphere Fluidics, University of Edinburgh, Horizon Discovery, OXGENE, and Twist Bioscience has culminated in a prototype automated microfluidic genome editing platform.

From Sphere Bio 12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

The research group of Deputy Principal Research Scientist Dr. Satoshi Uchida (Associate Professor, Kyoto Prefectural University of Medicine) at the Innovation Center of NanoMedicine (Director General: Prof. Kazunori Kataoka, Location: Kawasaki-Japan, Abbreviation: iCONM) reported that optimized nano-micelles can induce efficient genome editing in the mouse brain.

12 Mar 2021

Optimized nano-micelles can induce efficient genome editing in the mouse brain

12 Mar 2021

NIAID awards $2.5 million in grants to support research on bacteriophage therapy

The National Institute of Allergy and Infectious Diseases, part of the National Institutes of Health, has awarded $2.5 million in grants to 12 institutes around the world to support research on bacteriophage therapy.

11 Mar 2021

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

A team of researchers from the Agency for Science, Technology and Research's (A*STAR) Genome Institute of Singapore have developed a CRISPR-based gene editor, C-to-G Base Editor (CGBE), to correct mutations that cause genetic disorders.

11 Mar 2021

Study opens the door to new possibilities targeting telomeres to help treat cancer

The Telomeres and Telomerase Group led by Maria A. Blasco at the Spanish National Cancer Research Centre continues to make progress in unraveling the role that telomeres -the ends of chromosomes that are responsible for cellular aging as they shorten- play in cancer.

10 Mar 2021

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

In a recent bioRxiv* preprint paper, researchers isolated anti-RBD nanobodies from llamas and “nanomice” (they engineered to produce VHHs cloned from alpacas, dromedaries and camels).

10 Mar 2021

Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

Researchers in the US recently infected a series of human lung and head/neck cancer cell lines with SARS-CoV-2 that expressed varying levels of ACE2 and the TMPRSS2 protease to reassess their role in viral entrance.

8 Mar 2021

New method provides more control over gene drive releases

Powerful new genetic engineering methods have given scientists the potential to revolutionize several sectors of global urgency.

8 Mar 2021

New, efficient method facilitates antibody development

In recent years, therapeutic antibodies have transformed the treatment of cancer and autoimmune diseases.

5 Mar 2021

Insight into how plants sense zinc could help cultivate more nutritious crops

Over 2 billion people worldwide are malnourished due to zinc deficiency. Led by the University of Copenhagen, an international team of researchers has discovered how plants sense zinc and use this knowledge to enhance plant zinc uptake, leading to an increase in seed zinc content by 50 percent.

5 Mar 2021

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

With a relatively minor genetic change, a new treatment developed by researchers at the Georgia Institute of Technology and Emory University appears to stop replication of both flu viruses and the virus that causes Covid-19.

4 Mar 2021

PICI awards $3 million to support early career cancer researchers

From improving immunotherapy response in childhood cancer patients, to better understanding how cancer's spread to the liver affects the body's immune system, to helping T cells stay energized to fight cancer, The Parker Institute for Cancer Immunotherapy (PICI)'s 2021 class of early career researchers award recipients are pursuing ideas that have the potential to change the face of oncology.

3 Mar 2021

Unique nanoparticles can package and deliver gene-editing machinery to the liver

The genome editing technology CRISPR has emerged as a powerful new tool that can change the way we treat disease. The challenge when altering the genetics of our cells, however, is how to do it safely, effectively, and specifically targeted to the gene, tissue and organ that needs treatment.

2 Mar 2021

New technique uncovers the tricks used by cancer cells to evade immunotherapies

By harnessing the immune system against cancer, immunotherapies have revolutionized the way some types of cancer are treated. But most patients--across cancer types--do not respond, and in most cases, scientists are at a loss as to why.

1 Mar 2021

A region within GLI1 gene could potentially be targeted as cancer treatment

Scientists from the Stanley Manne Children's Research Institute at Ann & Robert H. Lurie Children's Hospital of Chicago found that a region within the DNA of the cancer-promoting GLI1 gene is directly responsible for regulating this gene's expression.

1 Mar 2021

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A novel targeted immunotherapy approach developed by researchers at the Ludwig Center, the Lustgarten Laboratory, and Bloomberg~Kimmel Institute for Cancer Immunotherapy at the Johns Hopkins Kimmel Cancer Center employs new antibodies against genetically altered proteins to target cancers.

1 Mar 2021

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Researchers from the Andalusian Centre for Molecular Biology and Regenerative Medicine (CABIMER), in collaboration with the Swiss Institute for Experimental Cancer Research (ISREC) have studied the mechanisms behind the higher tendency of people with Mulibrey syndrome to develop tumors.

26 Feb 2021

Immunologists map unknown biological machinery to produce memory T cells

Immunologists at St. Jude Children's Research Hospital have mapped the previously unknown biological machinery by which the immune system generates T cells that kill bacteria, viruses and tumor cells.

26 Feb 2021

CRISPR News and Research

Latest CRISPR News and Research

Genome-wide CRISPR screening used to identify factors essential for SARS-CoV-2 infection in humans

Optimizing The Genome Editing Workflow With Microfluidic Technology

Optimized nano-micelles can induce efficient genome editing in the mouse brain

Optimized nano-micelles can induce efficient genome editing in the mouse brain

NIAID awards $2.5 million in grants to support research on bacteriophage therapy

Novel CRISPR-based gene editor developed to correct mutations that cause genetic disorders

Study opens the door to new possibilities targeting telomeres to help treat cancer

Research demonstrates multivalent nanobodies overcome SARS-CoV-2 variant mutations

Study rethinks the role of ACE2 in SARS-CoV-2 viral entry

New method provides more control over gene drive releases

New, efficient method facilitates antibody development

Insight into how plants sense zinc could help cultivate more nutritious crops

New mRNA treatment appears to stop replication of flu and Covid-19 viruses

PICI awards $3 million to support early career cancer researchers

Unique nanoparticles can package and deliver gene-editing machinery to the liver

New technique uncovers the tricks used by cancer cells to evade immunotherapies

A region within GLI1 gene could potentially be targeted as cancer treatment

Researchers develop mutant gene-targeted immunotherapy approach to fight cancers

A missing protein explains the appearance of tumor cells in people with Mulibrey syndrome

Immunologists map unknown biological machinery to produce memory T cells

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