CRISPR News and Research

Latest CRISPR News and Research

Study implicates disruption in prenatal neurogenesis in the development of ASDs

A new study of autism risk genes by UC San Francisco and UC Berkeley scientists implicates disruption in prenatal neurogenesis - a process in which specialized "progenitor" cells give rise to new brain cells - in the development of autism spectrum disorders (ASDs).

8 Feb 2021

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

A new study by researchers at the University of Manchester, UK, reports on the compounds of interest that were identified as having potential for the treatment of COVID-19, from a library of almost 2,000 compounds from the APExBIO DiscoveryProbe library.

3 Feb 2021

New method identifies important mutations behind hereditary non-polyposis colorectal cancer

Colorectal cancer is the third most common form of cancer. While 90% of cases are in people older than 50, there is an as-yet unexplained rising incidence in younger people.

29 Jan 2021

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Researchers used single-molecule imaging to compare the genome-editing tools CRISPR-Cas9 and TALEN.

27 Jan 2021

Researchers identify foods that cause 90% of food allergies

The United States Department of Agriculture identifies a group of "big eight" foods that causes 90% of food allergies. Among these foods are wheat and peanuts.

27 Jan 2021

Suicide mosquitos may prevent the spread of Zika virus

In 2016, the World Health Organization called the Zika virus epidemic a "public health emergency of international concern" due to the virus causing birth defects for pregnant women in addition to neurological problems.

27 Jan 2021

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Astrocytes are the most abundant type of cells within the central nervous system (CNS), but they remain poorly characterized.

26 Jan 2021

Transcriptional regulator BRD2 as a potential therapeutic target for COVID-19

A team of international scientists has demonstrated that therapeutic inhibition of a transcriptional regulator BRD2, required for the endogenous expression of angiotensin-converting enzyme 2 (ACE2), can potentially suppress severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. The study is currently available on the bioRxiv* preprint server.

24 Jan 2021

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Popular in aquariums all over the world, the zebrafish is native to South Asia. But here in a Cincinnati Children's laboratory, the freshwater variant plays a vital role in scientific discovery.

22 Jan 2021

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Using SARS-CoV-2, a team of scientists from the United States has recently developed a bioengineered bacteriophage T4 nanoparticle structure using CRISPR technology that can be used as a universal platform to produce vaccines.

21 Jan 2021

Using gene therapy to mimic the effects of physical exercise

It sounds too good to be true - and it is. But Jose Bianco Moreira and the CERG research group at the Norwegian University of Science and Technology are convinced that some of the positive health effects of physical exercise can be achieved using gene therapy and medication.

21 Jan 2021

Eliminating key gene could revive exhausted immune cells to battle solid tumors

Eliminating a single gene can turn exhausted cancer-fighting immune cells known as CD8+ T cells back into refreshed soldiers that can continue to battle malignant tumors, a new study led by UT Southwestern researchers suggests.

20 Jan 2021

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Gene editing therapies, including CRISPR-Cas systems, offer the potential to correct mutations causing inherited retinal degenerations, a leading cause of blindness.

20 Jan 2021

Gene-cutting system may play second role as a genetic dimmer switch

In a series of experiments with laboratory-cultured bacteria, Johns Hopkins scientists have found evidence that there is a second role for the widely used gene-cutting system CRISPR-Cas9 -- as a genetic dimmer switch for CRISPR-Cas9 genes.

19 Jan 2021

Research finds new evidence about the mechanisms controlling skin repair and regeneration

As the air continues to dry and temperatures drop, the yearly battle against dry hands and skin has officially begun. New research from Northwestern University has found new evidence deep within the skin about the mechanisms controlling skin repair and renewal.

19 Jan 2021

Study reveals significant role of ADAMTS1 protein in uveal melanoma

Scientists from the University of Granada and GENYO (Pfizer-University of Granada-Andalusian Government Centre for Genomics and Oncological Research), in a study led by Juan Carlos Rodríguez-Manzaneque, have demonstrated the significant role of a protein called ADAMTS1 in uveal melanoma, one of the rarest and most aggressive cancers that exist, which develops in the eye.

15 Jan 2021

Researchers receive NIH grant to develop more effective flu vaccines

To build better vaccines, scientists want to know more about how our bodies make adequate numbers of effective, durable antibodies against the influenza virus.

11 Jan 2021

First steps toward uncovering CRISPR/Cas gene doping in plasma

All athletes want to be at the top of their game when they compete, but some resort to nefarious approaches to achieve peak muscle growth, speed and agility. Recent developments in gene editing technology could tempt athletes to change their DNA to get an edge.

6 Jan 2021

Truncating mutation locations tied to diversity, severity of autism symptoms

One of the most recognizable characteristics of autism is an amazing diversity of associated behavioral symptoms. Clinicians view autism as a broad spectrum of related disorders, and the origin of the disease's heterogeneity has puzzled scientists, doctors, and affected families for decades.

22 Dec 2020

Researchers use massive sequencing methods to identify rare genetic bone disorder

Researchers of the "Cell Biology and Physiology-LABRET" group of the University of Malaga (UMA), together with the Networking Biomedical Research Center in Bioengineering, Biomaterials and Nanomedicine (CIBER-BBN), have described a new genetic skeletal disorder based on a precision medicine strategy.

22 Dec 2020

CRISPR News and Research

Latest CRISPR News and Research

Study implicates disruption in prenatal neurogenesis in the development of ASDs

Researchers survey repurposed drugs that inhibit SARS-CoV-2 replication in vitro

New method identifies important mutations behind hereditary non-polyposis colorectal cancer

Study: TALEN is five times more efficient than CRISPR-Cas9 in tightly packed DNA

Researchers identify foods that cause 90% of food allergies

Suicide mosquitos may prevent the spread of Zika virus

Researchers find microbiome-controlled anti-inflammatory subsets of astrocytes

Transcriptional regulator BRD2 as a potential therapeutic target for COVID-19

UC research team uses zebrafish to study a gene mutation that causes congenital scoliosis

Researchers use SARS-CoV-2 to bioengineer universal vaccine platform

Using gene therapy to mimic the effects of physical exercise

Eliminating key gene could revive exhausted immune cells to battle solid tumors

Gene editing shows potential to correct mutations causing inherited retinal degeneration

Gene-cutting system may play second role as a genetic dimmer switch

Research finds new evidence about the mechanisms controlling skin repair and regeneration

Study reveals significant role of ADAMTS1 protein in uveal melanoma

Researchers receive NIH grant to develop more effective flu vaccines

First steps toward uncovering CRISPR/Cas gene doping in plasma

Truncating mutation locations tied to diversity, severity of autism symptoms

Researchers use massive sequencing methods to identify rare genetic bone disorder

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