CRISPR News and Research

Latest CRISPR News and Research

Researchers map sugar structures in 'library of sugars'

Most of us tend to think of sugar as a temptation that threatens our health. The reality is, however, that sugar is an essential component of the human body; it covers the surface of our cells and proteins, and tunes the behaviour and function of our tissues in both health and disease.

14 Aug 2018

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Genome editing using the CRISPR-Cas9 system has tremendous promise for therapeutic correction of genetic errors in human cells. Prior to adoption as a medical therapeutic, safety concerns relating to off-target effects must be minimized to mitigate risks that may arise from the unintended action of this system at sites similar, but not identical, to the desired gene target site.

From Integrated DNA Technologies 10 Aug 2018

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Ashleigh Schaffer, PhD, assistant professor of genetics at Case Western Reserve University School of Medicine, and a team of global genetics experts have discovered a genetic mutation and the faulty development process it triggers, causing a debilitating brain-based disorder in children.

9 Aug 2018

Researchers identify new regulator in breast cancer cells

Triple-negative breast cancer is a particularly aggressive form of breast cancer. Here, important receptors are missing, which often serve as targets for treatments.

6 Aug 2018

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

A Massachusetts General Hospital research team has used epigenome editing tools to investigate how the genetic abnormality that drives Ewing sarcoma - the second most common bone cancer in children and young adults - unleashes tumor growth.

2 Aug 2018

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

A group of researchers at the University of São Paulo in Brazil used a DNA editing tool called CRISPR/Cas9 to manipulate on of the genes associated to the autoaggressive T lymphocytes responsible for inducing autoimmune diseases such as autoimmune polyglandular syndrome type 1 and type 1 diabetes.

2 Aug 2018

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Scientists at the Innovative Genomics Institute have concocted a transformative new way to harness the power of evolution.

2 Aug 2018

Two new studies could improve treatment for patients with diabetes

Researchers have developed a novel test that rapidly distinguishes between type 1 and type 2 diabetes. This new method and a second study revealing gaps in care for women with gestational diabetes were presented today at the 70th AACC Annual Scientific Meeting & Clinical Lab Expo, and could improve treatment for patients with all diabetes types across the board.

1 Aug 2018

Vitamin D supplementation could significantly improve quality of life for RA patients

Scientists have discovered that in rheumatoid arthritis patients, lower levels of vitamin D are associated with increased disease severity.

1 Aug 2018

Research: Two out of three at-home ovulation tests do not provide accurate results

Research announced today at the 70th AACC Annual Scientific Meeting & Clinical Lab Expo reveals that two out of three of the digital home ovulation tests sold by U.S. retailers do not accurately predict when a woman is ovulating.

31 Jul 2018

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Despite high hopes and high investment in CRISPR-Cas9 gene editing, scientists still have a lot to learn about how it works in humans.

31 Jul 2018

Researchers discover various mechanisms of resistance to cancer therapy

An international research team under the co-direction of the University of Bern and the Netherlands Cancer Institute has discovered various mechanisms of resistance to cancer therapy. The findings help researchers to understand the self-repair of cancer cells after a therapy and thus help to fight resistant tumours more efficiently.

30 Jul 2018

Most Americans skeptical about gene editing

A new survey from Pew Research Center has found that nearly half of the surveyed Americans believe that in the coming 50 years, nearly all genetic birth defects could be eliminated due to advances in gene editing.

26 Jul 2018

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

A team of researchers at the University of Cambridge has identified a protein complex that might explain why some cancer patients treated with the revolutionary new anti-cancer drugs known as PARP inhibitors develop resistance to their medication.

25 Jul 2018

MODEL-AD Center releases eight new mouse models for Alzheimer's research

The MODEL-AD Center, an ambitious project to develop and distribute precise mouse models of late-onset Alzheimer's disease (AD), has released eight new models carrying genetic mutations found in patients.

23 Jul 2018

Mysterious molecule Yin Yang may fuel tumor growth in breast cancer

Scientists have unveiled clues about a mysterious molecule called Yin Yang1 - and revealed it may fuel tumor growth in breast cancer.

23 Jul 2018

New breeding technologies could enhance shape, size, color, and health benefits of produce

Forget vegetables with dull colors and fuzzy skin or fruits that lack of flavor--the produce aisle of the future could offer plant products that are designed for creative cooks and fussy eaters.

20 Jul 2018

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers at the University of Oulu in Finland have discovered novel genes and mechanisms that can explain how a genomic variant in a single nucleotide polymorphism rs11672691 influences prostate cancer aggressiveness.

20 Jul 2018

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

CRISPR, or clustered regularly interspaced short palindromic repeats, are an essential part of bacterial immunity designed to defend against foreign DNA. In bacteria, CRISPR acts just like it does in human cells as a pair of scissors, in their case with the goal of cutting strands of infecting DNA.

20 Jul 2018

Researchers identify enzyme as potential new drug target for blood disorders

Medical researchers have identified a key signaling protein that regulates hemoglobin production in red blood cells, offering a possible target for a future innovative drug to treat sickle cell disease.

20 Jul 2018

CRISPR News and Research

Latest CRISPR News and Research

Researchers map sugar structures in 'library of sugars'

Using CRISPR-Cas9 genome editing to correct mutation responsible for sickle cell disease

Researchers discover genetic mutation underlying debilitating childhood brain disorder

Researchers identify new regulator in breast cancer cells

MGH researchers explore how genetic abnormality in Ewing sarcoma unleashes tumor growth

Researchers use DNA editing tool to reveal mechanisms behind autoimmune diseases

Innovative 'EvolvR' system lets scientists shuffle genes until they get right variation

Two new studies could improve treatment for patients with diabetes

Vitamin D supplementation could significantly improve quality of life for RA patients

Research: Two out of three at-home ovulation tests do not provide accurate results

Scientists find people's assumptions about DNA repair after CRISPR editing to be wrong

Researchers discover various mechanisms of resistance to cancer therapy

Most Americans skeptical about gene editing

New protein complex may explain why patients develop resistance to novel anti-cancer drugs

MODEL-AD Center releases eight new mouse models for Alzheimer's research

Mysterious molecule Yin Yang may fuel tumor growth in breast cancer

New breeding technologies could enhance shape, size, color, and health benefits of produce

Researchers uncover cause for progression of prostate cancer to incurable stage

Researchers present evidence of phage cooperation when attacking CRISPR-containing bacteria

Researchers identify enzyme as potential new drug target for blood disorders

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production