Chromosome News and Research

Latest Chromosome News and Research

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

All living things--from dandelions to reindeer--evolve over time. Cancer cells are no exception, and are subject to the two overarching mechanisms described by Charles Darwin: chance mutation and natural selection.

3 Apr 2015

Study: 'Open' stem cell chromosomes hold great promise for treating liver, pancreas diseases

Stem cells hold great promise for treating a number of diseases, in part because they have the unique ability to differentiate, specializing into any one of the hundreds of cell types that comprise the human body.

2 Apr 2015

New prenatal test introduced for detecting Down’s Syndrome

A new prenatal test for Down’s Syndrome may be more effective at diagnosing the condition than the standard screening that is currently used, suggests a study published in the New England Journal of Medicine.

2 Apr 2015

Novel molecule inhibits cancer-causing transcription factors

A novel molecule designed by scientists at the University of Massachusetts Medical School and the University of Virginia inhibits progression of a hard-to-treat form of recurring acute myeloid leukemia (AML) in patient tissue.

2 Apr 2015

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

Lung diseases like emphysema and pulmonary fibrosis are common among people with malfunctioning telomeres, the “caps” or ends of chromosomes. Now, researchers from Johns Hopkins say they have discovered what goes wrong and why.

1 Apr 2015

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

1 Apr 2015

Big data helps discover gephyrin protein's connection in human history

Big data: It's a term we read and hear about often, but is hard to grasp. Computer scientists at Washington University in St. Louis' School of Engineering & Applied Science tackled some big data about an important protein and discovered its connection in human history as well as clues about its role in complex neurological diseases.

30 Mar 2015

Research: Common bacteria poised to become antibiotic-resistant superbugs

Antibiotic resistance is poised to spread globally among bacteria frequently implicated in respiratory and urinary infections in hospital settings, according to new research at Washington University School of Medicine in St. Louis.

30 Mar 2015

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

A blood test may shed new light on Fragile X syndrome related disorders in women, according to a new study published in the March 25, 2015, online issue of Neurology, the medical journal of the American Academy of Neurology. Fragile X is the most common inherited form of intellectual disability and the most frequent genetic cause of autism.

30 Mar 2015

Iceland paint a genomic picture for an entire nation

Researchers in Iceland have published the largest ever studies of whole-genome data and effectively deduced the genetic code of “an entire nation.”

26 Mar 2015

Position statement on promise, challenges of non-invasive prenatal testing

Two of the world's largest professional societies of human geneticists have issued a joint position statement on the promise and challenges of non-invasive prenatal testing (NIPT), a new procedure to test blood drawn from pregnant mothers for Down syndrome and other chromosomal disorders in the fetus.

26 Mar 2015

Mount Sinai researchers reprogram blood cells into iPSCs to study genetic origins of MDS

Induced pluripotent stem cells (iPSCs) -- adult cells reprogrammed back to an embryonic stem cell-like state--may better model the genetic contributions to each patient's particular disease. In a process called cellular reprogramming, researchers at Icahn School of Medicine at Mount Sinai have taken mature blood cells from patients with myelodysplastic syndrome (MDS) and reprogrammed them back into iPSCs to study the genetic origins of this rare blood cancer.

26 Mar 2015

Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

Kidney transplantation outcomes from deceased African-American donors may improve through rapid testing for apolipoprotein L1 gene (APOL1) renal risk variants at the time of organ recovery, according to a new study led by researchers at Wake Forest Baptist Medical Center.

25 Mar 2015

Fourth-line bosutinib ‘appropriate’ after prior CML treatment failure, intolerance

A Spanish study suggests that bosutinib can help improve or maintain response in patients with chronic myeloid leukaemia after treatment failure of three previous tyrosine kinase inhibitors.

24 Mar 2015

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

The DNA you inherit from your parents contributes to the physical make-up of your body -- whether you have blue eyes or brown, black hair or red, or are male or female.

23 Mar 2015

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

Pharmacyclics, Inc. today announced that new pre-clinical and clinical data for ibrutinib (IMBRUVICA) will be highlighted at the 2015 American Association for Cancer Research Annual Meeting to be held April 18 – 22, 2015, in Philadelphia, PA.

19 Mar 2015

RMANJ acquires IVF New Jersey

Reproductive Medicine Associates of New Jersey, a world-renowned leader in the field of infertility, today announced the strategic acquisition of IVF New Jersey Fertility and Gynecology Center, one of the largest fertility centers in New Jersey.

18 Mar 2015

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

An Indiana University cancer researcher and her colleagues have identified genetic markers that may help determine who benefits from regular use of aspirin and other nonsteroidal anti-inflammatory drugs for lowering one's risk of developing colorectal cancer.

18 Mar 2015

DNA sequence determines flexibility, stability of DNA package inside microscopic cell

To pack two meters of DNA into a microscopic cell, the string of genetic information must be wound extremely carefully into chromosomes. Surprisingly the DNA's sequence causes it to be coiled and uncoiled much like a yoyo, scientists reported in Cell.

18 Mar 2015

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

In 1953 Watson and Crick first published the discovery of the double helix structure of the DNA. They were able to visualize the DNA structure by means of X-Ray diffraction. Techniques, such as electron microscopy, allowed scientists to identify nucleosomes, the first and most basic level of chromosome organisation

13 Mar 2015

Chromosome News and Research

Latest Chromosome News and Research

Research may point to new paradigms in diagnosis, treatment of aggressive cancers

Study: 'Open' stem cell chromosomes hold great promise for treating liver, pancreas diseases

New prenatal test introduced for detecting Down’s Syndrome

Novel molecule inhibits cancer-causing transcription factors

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

Johns Hopkins researchers find link between premature aging of telomere and lung diseases

Big data helps discover gephyrin protein's connection in human history

Research: Common bacteria poised to become antibiotic-resistant superbugs

Study: Blood test may help diagnose Fragile X syndrome related disorders in women

Iceland paint a genomic picture for an entire nation

Position statement on promise, challenges of non-invasive prenatal testing

Mount Sinai researchers reprogram blood cells into iPSCs to study genetic origins of MDS

Testing APOL1 gene variants in deceased kidney donors may improve transplant outcomes

Fourth-line bosutinib ‘appropriate’ after prior CML treatment failure, intolerance

Male genetic diversity declined due to wealth, power rather than `survival of fittest`

New pre-clinical, clinical data for IMBRUVICA to be highlighted at AACR Annual Meeting

RMANJ acquires IVF New Jersey

Genetic markers may help decide who benefits from aspirin, NSAIDs in lowering risk of colorectal cancer

DNA sequence determines flexibility, stability of DNA package inside microscopic cell

Super-resolution microscopes reveal the link between genome packaging and cell pluripotency

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Chromosome News and Research

Latest Chromosome News and Research

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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