Cytokines News and Research

Latest Cytokines News and Research

Identification of common genes in COVID-19 and COPD

Based on protein-protein interactions, the paper shows the presence of ten genes that overlap between the two illnesses, also shared by several other deadly and debilitating diseases.

2 Nov 2021

Investigation of Budesonide's mechanism of action against SARS-CoV-2

Researchers look to gain an understanding of the mechanism of action of budesonide in improving the prognosis of patients with SARS-CoV-2 infection.

1 Nov 2021

Study finds inhaled microspheres reduce SARS-CoV-2 infective effectiveness

A new study develops an inhaled microfluidic microsphere with a genetically engineered membrane from the ACE2 receptor-overexpressing cells and macrophages.

1 Nov 2021

Alteration in gut microbiome may lead to hyperinflammation in severe COVID-19

A team of international scientists has recently identified a distinct set of proinflammatory mediators and metabolites associated with the fatal consequences of severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection. Moreover, they have established a link between gut microbiome alteration and hyper-inflammatory response in patients with severe COVID-19. The study is currently available on the bioRxiv* preprint server.

1 Nov 2021

Researchers decipher when and why T cells become non-responsive to immunotherapy

Non-small cell lung cancer is the most common type of lung cancer in humans. Some patients with NSCLC receive a therapy called immune checkpoint blockade (ICB) that helps kill cancer cells by reinvigorating a subset of immune cells called T cells, which are "exhausted" and have stopped working.

30 Oct 2021

UAB researchers show how to identify non-responding tumors and improve immunotherapy response

Immunotherapy using checkpoint inhibitors can work well to treat cancer, but only a minority of patients respond to therapy.

28 Oct 2021

How long does natural or vaccine-induced immunity to COVID last?

Researchers present a comprehensive assessment on SARS-CoV-2 induced immunity.

28 Oct 2021

Using fluvoxamine to treat COVID-19 patients reduces the need for prolonged hospitalization, trial shows

The results of a new randomized clinical trial, published in The Lancet Global Health, have demonstrated that using fluvoxamine to treat high-risk outpatients with early-diagnosed COVID-19 reduced the need for prolonged observation in an emergency setting or hospitalization, compared to a control group who received a placebo.

28 Oct 2021

Brain fog in long COVID

A new study explores one troubling manifestation of long COVID, which is the cognitive impairment that follows clinical resolution of COVID-19.

26 Oct 2021

Fermented soy product suppresses airway inflammation in animal models of asthma

Bronchial asthma causes symptoms such as wheezing and cough due to chronic airway inflammation, but there is no fundamental treatment for it, leaving a desire for new prevention and treatment methods.

26 Oct 2021

Sexually dimorphic placental antibody transfer during SARS-CoV-2 infection

In a paper recently published in the journal Science Translational Medicine by Bordt et al. (October 19th, 2021), maternal SARS-CoV-2 infections are studied with particular regard to maternal-fetal antibody transfer and virus-induced placental interferon responses, finding a sexually dimorphic response that results in lesser antibody transfer to the male fetus.

26 Oct 2021

Targeting SARS-CoV-2 with Chaga mushroom – a natural antiviral compound

A new study examines the potential binding interaction of the beneficial components of Chaga mushroom with that of the SARS-CoV-2 RBD.

24 Oct 2021

Study reveals key role of fat cells in cognitive decline and neurodegeneration

Findings published this week reveal new insights into the role of fat cells in cognitive decline and neurodegeneration, according to a study that involves the oxidant amplification loop led by Marshall University scientists.

22 Oct 2021

Chemical substance may specifically inhibit both SARS-CoV-2 proteases and human protease

Researchers tested analogs of disulfiram on SARS-CoV-2 Mpro and PLpro to find more efficient and effective inhibitors that take advantage of disulfiram’s mechanism of binding to the cysteine residue.

22 Oct 2021

Using saliva to predict COVID-19 severity in children

News-Medical speaks to Dr. Usha Sethuraman about her research into COVID-19 and how saliva could be used to help predict COVID-19 severity in children.

22 Oct 2021

Scientists search for cause of mysterious covid-related inflammation in children

Like most other kids with covid, Dante and Michael DeMaino seemed to have no serious symptoms.

20 Oct 2021

Novel approach to predict outcomes in COVID-19 patients

In a recent study, researchers have used the predictive power of chest CT scans and plasma cytokines to predict death and severity in COVID-19 patients.

19 Oct 2021

Nasal delivery of single-domain antibodies improves SARS-CoV-2 symptoms in animal model

In a recent study published in the journal PLOS Pathogens, scientists showed that nasal administration of a single-domain antibody (VHH), named K-874A, brought about inhibition of SARS-CoV-2 titers in infected lungs of Syrian hamsters.

19 Oct 2021

SARS-CoV-2 antibodies detected in breast milk of vaccinated mothers

Now, a new medRxiv* preprint study finds mothers vaccinated either one of the messenger RNA (mRNA) vaccines transferred neutralizing antibodies and cytokines, including interferon-gamma (IFNγ), to a breastfeeding child. Additionally, the humoral response in breastmilk was effective in neutralizing four variants of concern.

18 Oct 2021

Phase 2 study shows safety and immunogenicity of SARS-CoV-2 recombinant protein vaccine

The results of a phase 2 clinical trial featuring a SARS-CoV-2 recombinant protein vaccine developed by GlaxoSmithKline are reported, demonstrating a favorable immune response amongst both naïve and non-naïve adults with an acceptable safety profile.

15 Oct 2021