Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Researchers from the Institute of Neurosciences of the UB and from IDIBAPS together with a team from the University Pierre and Marie Curie and the Institute du Fer à Moulin, published a study in Nature Communications, which demonstrates that the regulation in Pyk2, a protein-tyrosine kinase, causes alterations of the synaptic plasticity involved in memory tasks, associated with the hippocampus in mouse models of neurodegenerative diseases, such as Huntington's.

13 Jun 2017

Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature

A Loyola University Chicago study has found that abnormal proteins found in Alzheimer's disease, Parkinson's disease, and Huntington's disease all share a similar ability to cause damage when they invade brain cells.

23 May 2017

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Scientists at the University of Sussex have started work on a multi-million pound project to develop drugs to treat the debilitating loss of cognitive function associated with Huntington's disease.

19 May 2017

Researchers discover how tau disrupts functioning of nerve cells even before forming tangles

Tau proteins are involved in more than twenty neurodegenerative diseases, including various forms of dementia.

19 May 2017

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome.

17 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

The blood-brain barrier is biology's proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.

17 May 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

UCLA study traces Pavlovian response to small cluster of brain cells

In his famous experiment, Russian scientist Ivan Pavlov rang a bell each time he fed his dogs. Soon, the dogs began drooling in anticipation when they heard the bell, even before food appeared.

22 Mar 2017

Stem cells strictly abide by innate developmental clocks, study shows

The mystery of what controls the range of developmental clocks in mammals — from 22 months for an elephant to 12 days for an opossum — may lie in the strict time-keeping of pluripotent stem cells for each unique species.

28 Feb 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Pyk2 deficits contribute to memory problems in Huntington’s disease mouse model

Study: Abnormal proteins in Alzheimer's, Parkinson's, and Huntington's diseases share similar feature

Scientists to develop drugs for treating cognitive deficits in Huntington's disease sufferers

Researchers discover how tau disrupts functioning of nerve cells even before forming tangles

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Easing cellular traffic jams in Huntington’s disease may save brain cells

New study finds link between neural tube defects in infants and neurodegenerative diseases

EPFL scientists develop synthetic methods to crack code of Huntington's disease

UCLA study traces Pavlovian response to small cluster of brain cells

Stem cells strictly abide by innate developmental clocks, study shows

Study finding suggests new ways in which genetic mutations may cause brain disorders

Discovery of early biomarkers paves way for new insight into Huntington's disease

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

Duke Health researchers identify potential new drug target for Huntington's disease

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Designer compound may be effective tool for tackling tau-related disorders

Both accelerator and brake in the brain control all types of movements, research shows

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

eBook: Advancing neurodegenerative research with iPSC-derived microglia models eBook

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production

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