Huntington's Disease News and Research

Latest Huntington's Disease News and Research

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Scientists for the first time have assembled a "disease in a dish" model that pinpoints how a defect in the blood-brain barrier can produce an incurable psychomotor disorder, Allan-Herndon-Dudley syndrome.

17 May 2017

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

By using induced pluripotent stem cells to create endothelial cells that line blood vessels in the brain for the first time for a neurodegenerative disease, University of California, Irvine neurobiologists and colleagues have learned why Huntington's disease patients have defects in the blood-brain barrier that contribute to the symptoms of this fatal disorder.

17 May 2017

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

The blood-brain barrier is biology's proverbial double-edged sword. An impermeable shield of endothelial cells that protects our brains from toxins and other threats that may lurk in circulating blood, the barrier can also exclude therapeutic drugs and, at times, essential biomolecules required for healthy brain development.

17 May 2017

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Sangamo Therapeutics, Inc. and Pfizer Inc. today announced an exclusive, global collaboration and license agreement for the development and commercialization of gene therapy programs for Hemophilia A, including SB-525, one of Sangamo's four lead product candidates, which Sangamo expects will enter the clinic this quarter.

11 May 2017

Easing cellular traffic jams in Huntington’s disease may save brain cells

Working with mouse, fly and human cells and tissue, Johns Hopkins researchers report new evidence that disruptions in the movement of cellular materials in and out of a cell's control center - the nucleus- appear to be a direct cause of brain cell death in Huntington's disease, an inherited adult neurodegenerative disorder.

5 May 2017

New study finds link between neural tube defects in infants and neurodegenerative diseases

A new study has found a link between neurological birth defects in infants commonly found in pregnant women with diabetes and several neurodegenerative diseases, including Alzheimer's, Parkinson's and Huntington's diseases.

10 Apr 2017

EPFL scientists develop synthetic methods to crack code of Huntington's disease

Huntington's disease is a neurodegenerative disorder that causes patients to lose their ability to move, speak, and even think. It is caused by a gene mutation that produces an abnormal form of the protein huntingtin, which aggregates and builds up inside neurons of the cortex and striatum.

23 Mar 2017

UCLA study traces Pavlovian response to small cluster of brain cells

In his famous experiment, Russian scientist Ivan Pavlov rang a bell each time he fed his dogs. Soon, the dogs began drooling in anticipation when they heard the bell, even before food appeared.

22 Mar 2017

Stem cells strictly abide by innate developmental clocks, study shows

The mystery of what controls the range of developmental clocks in mammals — from 22 months for an elephant to 12 days for an opossum — may lie in the strict time-keeping of pluripotent stem cells for each unique species.

28 Feb 2017

Study finding suggests new ways in which genetic mutations may cause brain disorders

Many kids say they love their mom and dad equally, but there are times when even the best prefers one parent over the other. The same can be said for how the body's cells treat our DNA instructions. It has long been thought that each copy - one inherited from mom and one from dad - is treated the same. A new study from scientists at the University of Utah School of Medicine shows that it is not uncommon for cells in the brain to preferentially activate one copy over the other.

25 Feb 2017

Discovery of early biomarkers paves way for new insight into Huntington's disease

Early warning signs of Huntington's disease have been uncovered in a sheep carrying the human HD mutation, leading the way for new insight into this devastating illness, a new study in Scientific Reports has found.

22 Feb 2017

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

Biologists have known for decades that enduring a short period of mild stress makes simple organisms and human cells better able to survive additional stress later in life.

15 Feb 2017

Duke Health researchers identify potential new drug target for Huntington's disease

The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

13 Feb 2017

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Rutgers scientists say neurodegenerative diseases like Alzheimer's and Parkinson's may be linked to defective brain cells disposing toxic proteins that make neighboring cells sick.

10 Feb 2017

Designer compound may be effective tool for tackling tau-related disorders

In a study of mice and monkeys, National Institutes of Health funded researchers showed that they could prevent and reverse some of the brain injury caused by the toxic form of a protein called tau.

8 Feb 2017

Both accelerator and brake in the brain control all types of movements, research shows

In order to drive a car, you need a good balance between accelerator and brake. The same applies to a part of the brain - the striatum - that controls our movements.

28 Jan 2017

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Under ordinary circumstances, the protein tau contributes to the normal, healthy functioning of brain neurons. In some people, though, it collects into toxic tangles that damage brain cells.

25 Jan 2017

Survey reports symptoms and treatments that impact lives of HD patients and caregivers

Huntington's disease (HD) has no cure and no therapies to slow the course of this fatal disease. HD patients can experience a wide range of cognitive, physical, and psychiatric symptoms.

24 Jan 2017

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

The brain is home to two kinds of cells: neurons and glia, with the latter protecting the former. Glia, the stuff between neurons, are important also because they regulate and define neuron-neuron communication.

9 Jan 2017

UNC Catalyst aims to provide knowledge and research tools to tackle rare diseases

Freely giving researchers the tools and knowledge to tackle rare and orphaned diseases is the mission of UNC Catalyst, a new endeavor the University of North Carolina at Chapel Hill has launched with a $2 million grant from the Eshelman Institute for Innovation.

5 Jan 2017

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

‘Disease in a dish’ model pinpoints how defects in blood-brain barrier can cause psychomotor disorder

Neurobiologists uncover reason for defects in the blood-brain barrier of Huntington's disease patients

Scientists use AHDS patients’ cells to recreate disease and mimic blood-brain barrier

Sangamo Therapeutics and Pfizer team up for development of Hemophilia A gene therapy

Easing cellular traffic jams in Huntington’s disease may save brain cells

New study finds link between neural tube defects in infants and neurodegenerative diseases

EPFL scientists develop synthetic methods to crack code of Huntington's disease

UCLA study traces Pavlovian response to small cluster of brain cells

Stem cells strictly abide by innate developmental clocks, study shows

Study finding suggests new ways in which genetic mutations may cause brain disorders

Discovery of early biomarkers paves way for new insight into Huntington's disease

SBP scientists identify autophagy linked to beneficial effects of enduring temporary stress

Duke Health researchers identify potential new drug target for Huntington's disease

Defective brain cells disposing toxic proteins may be linked to neurodegenerative diseases

Designer compound may be effective tool for tackling tau-related disorders

Both accelerator and brake in the brain control all types of movements, research shows

Synthetic molecule appears to reverse Alzheimer's-related neurological damage

Survey reports symptoms and treatments that impact lives of HD patients and caregivers

The 10th annual symposium at UC Riverside focuses on glial-neuronal interactions in health and disease

UNC Catalyst aims to provide knowledge and research tools to tackle rare diseases

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

Huntington's Disease News and Research

Latest Huntington's Disease News and Research

Human iPSCs: A Full Guide to Advanced in Vitro Models and Applications eBook

CellVoyant's AI-Powered Vision for the Future of Cell Therapy

Scalable, Smart, and Accessible: The Future of Lab Automation

Healthy Beginnings, Hopeful Futures: A Conversation with WHO’s Dr. Allotey

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