Metabolism News and Research

Latest Metabolism News and Research

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

A new Cleveland Clinic study has identified diet-derived molecules called metabolites as main drivers of young-onset colorectal cancer risk, especially those associated with red and processed meat.

14 Aug 2024

Very-low-calorie keto diet slashes fat and oxidative stress, boosting metabolic health in obesity

Study reveals that an 11-week, very-low-calorie ketogenic diet significantly reduces body fat and improves glucose metabolism in obese individuals, while also lowering oxidative stress markers, indicating better overall metabolic health.

14 Aug 2024

Midlife and early senior years marked by dramatic molecular shifts

If it's ever felt like everything in your body is breaking down at once, that might not be your imagination. A new Stanford Medicine study shows that many of our molecules and microorganisms dramatically rise or fall in number during our 40s and 60s.

14 Aug 2024

Ketogenic diet can boost efficacy of pancreatic cancer therapy

A study of fasting and the ketogenic diet reveals a new vulnerability of pancreatic tumors to an existing cancer drug.

14 Aug 2024

Finnish study links autumn and winter births to higher rates of asthma and allergic rhinitis

Being born in autumn or winter is associated with asthma and allergic rhinitis in Finland, a new registry-based study shows.

14 Aug 2024

Study finds no clinically useful biomarkers for long COVID in routine lab tests

Whether tests in current use were adequate to identify post-acute sequelae of SARS-CoV-2 (PASC).

14 Aug 2024

Personalized treatment strategies based on calcification status in breast cancer

Mammographic calcifications, a common feature of breast cancer, have remained enigmatic in terms of their molecular underpinnings and clinical implications, particularly in the hormone receptor-positive, HER2-negative subtype.

13 Aug 2024

IU research sheds light on urea cycle defects and fatty liver disease

An Indiana University School of Medicine physician scientist is making strides in understanding the molecular origins of fatty liver disease, a leading cause of liver failure in the United States.

13 Aug 2024

Higher heme iron intake linked to increased risk of type 2 diabetes

Higher intake of heme iron, the type found in red meat and other animal products-;as opposed to non-heme iron, found mostly in plant-based foods-;was associated with a higher risk of developing type 2 diabetes (T2D) in a new study led by researchers at Harvard T.H. Chan School of Public Health.

13 Aug 2024

Study uncovers OLAH as key driver of fatal respiratory disease

Respiratory infections can be severe, even deadly, in some individuals, but not in others.

12 Aug 2024

Study shows decline in sugar consumption among youth but levels remain above WHO guidelines

A high-sugar diet is seen as a risk factor for obesity and chronic illness.

12 Aug 2024

Inflammation during pregnancy impacts child neurodevelopment

When a person experiences an injury or infection, the body's immune system responds with inflammation to start the healing process. However, inflammation can occur in much less helpful circumstances – for example, when a person experiences psychological stress or consistently eats a poor diet high in sugars, fats, and processed foods.

9 Aug 2024

Study identifies brain circuit that balances hunger-driven and pleasure-driven eating

People eat either because they are hungry or for pleasure, even in the absence of hunger. While hunger-driven eating is fundamental for survival, pleasure-driven feeding may accelerate the onset of obesity and associated metabolic disorders.

9 Aug 2024

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Insilico Medicine ("Insilico"), a clinical-stage generative artificial intelligence (AI)-driven biotechnology company, today announced ISM6331, potential best-in-class pan-TEAD inhibitor, has received the U.S. Food and Drug Administration (FDA) Investigational New Drug (IND) clearance for the treatment of mesothelioma, following the grant of Orphan Drug Designation (ODD) in June 2024. It brings the total number of IND-approved molecules of Insilico to nine.

8 Aug 2024

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Nationally, falls remain the leading cause of both fatal and non-fatal injuries in older adults and are the leading cause of traumatic brain injury.

8 Aug 2024

Low-acid diets with fruits and vegetables significantly improve kidney and heart health in hypertension patients

Study found that low-acid diets, particularly those rich in fruits and vegetables, offer significant kidney and cardiovascular protection in patients with primary hypertension, outperforming traditional medical care.

8 Aug 2024

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Researchers at Columbia University Mailman School of Public Health, the University of North Carolina at Chapel Hill and at the National Academy of Sciences of Ukraine used the setting of the man-made Ukrainian Holodomor famine of 1932-1933 to examine the relation between prenatal famine and adult Type 2 diabetes mellitus (T2DM).

8 Aug 2024

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Women with the common reproductive and metabolic condition polycystic ovary syndrome (PCOS) face a greater risk of developing bulimia, binge eating disorder and disordered eating, according to new research published in The Journal of Clinical Endocrinology & Metabolism.

8 Aug 2024

Review of fasting-mimicking diets in cancer treatment

Researchers present the role of cyclic fasting and fasting-mimicking diets (FMD) in cancer therapy.

8 Aug 2024

Consuming foods with erythritol increases risk of cardiovascular events, study shows

New Cleveland Clinic research shows that consuming foods with erythritol, a popular artificial sweetener, increases risk of cardiovascular events such as heart attack and stroke.

8 Aug 2024

Metabolism News and Research

Latest Metabolism News and Research

Diet-derived molecules identified as main drivers of young-onset colorectal cancer risk

Very-low-calorie keto diet slashes fat and oxidative stress, boosting metabolic health in obesity

Midlife and early senior years marked by dramatic molecular shifts

Ketogenic diet can boost efficacy of pancreatic cancer therapy

Finnish study links autumn and winter births to higher rates of asthma and allergic rhinitis

Study finds no clinically useful biomarkers for long COVID in routine lab tests

Personalized treatment strategies based on calcification status in breast cancer

IU research sheds light on urea cycle defects and fatty liver disease

Higher heme iron intake linked to increased risk of type 2 diabetes

Study uncovers OLAH as key driver of fatal respiratory disease

Study shows decline in sugar consumption among youth but levels remain above WHO guidelines

Inflammation during pregnancy impacts child neurodevelopment

Study identifies brain circuit that balances hunger-driven and pleasure-driven eating

Insilico Medicine's pan-TEAD inhibitor ISM6331 receives FDA IND clearance for mesothelioma treatment

Alcohol use in older adults linked to increased risk of severe head trauma after falls

Low-acid diets with fruits and vegetables significantly improve kidney and heart health in hypertension patients

Prenatal famine exposure tied to higher risk of Type 2 diabetes

Polycystic ovary syndrome linked to greater risk of disordered eating in women

Review of fasting-mimicking diets in cancer treatment

Consuming foods with erythritol increases risk of cardiovascular events, study shows

Small solutions for big problems in drug discovery and delivery

Professor Nancy Ip: Pioneering New Paths in Neurodegenerative Therapy

Utilizing process Raman in optimizing cultivated meat production