Metabolism News and Research

Latest Metabolism News and Research

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Sepsis continues to be a leading cause of mortality in ICUs worldwide. Despite advances in early detection and treatment, standardized antibiotic dosing frequently ignores patient-level variability-especially that associated with sex-related physiology and gender-influenced care disparities.

31 Oct 2025

Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis

A researcher at the University of Houston finds management of diabetic ketoacidosis may center around reducing ketone levels in diabetic patients and increasing exercise capacity for better health outcomes.

30 Oct 2025

Two microbial metabolites compete to control the cells' protein building machinery

The microbiome-the trillions of bacteria, viruses, and fungi that live quietly in our body-plays a crucial role in shaping human health by providing a variety of micronutrients necessary for vital functions.

30 Oct 2025

Does fasting earlier in the day improve metabolism? This study says no

In a randomized crossover trial of 31 women with overweight, early and late time-restricted eating (TRE) produced no improvement in insulin sensitivity or cardiometabolic markers under isocaloric conditions. Both schedules, however, shifted internal circadian clocks, highlighting that meal timing affects biological rhythms more than metabolic outcomes.

30 Oct 2025

Aligning your body clock may protect your heart and metabolism, says AHA

A new American Heart Association scientific statement highlights how maintaining circadian health through regular sleep, light exposure, meal timing, and exercise may reduce cardiometabolic disease risk. Disrupting these daily rhythms can impair glucose regulation, blood pressure, and cardiovascular function.

29 Oct 2025

AI indelibly transforms solid tumor drug development

Artificial intelligence (AI) is fundamentally reshaping the landscape of solid tumor (ST) drug development.

29 Oct 2025

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

An experimental compound reduced the cell death, inflammation, and organ damage seen with diabetes.

29 Oct 2025

Hydroxytyrosol from olives shows new promise as a brain-protective compound

This review highlights hydroxytyrosol's role as a neuroprotective agent, activating key pathways for mental and vascular health through olive-derived compounds.

29 Oct 2025

Circadian rhythm disruptions may increase the risk of cardiovascular disease

As modern lifestyles increasingly challenge the body's natural circadian rhythm, the American Heart Association is spotlighting the potential health consequences of regular disruptions to our body's internal clock with a new scientific statement published today in its flagship journal Circulation.

28 Oct 2025

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

A new UCLA study reveals that breast milk from women living with HIV contains significantly lower levels of tryptophan, an essential amino acid likely important for infant immune function, growth, and brain development.

28 Oct 2025

Researchers discover a previously unknown genetic cause for microcephaly

Microcephaly is a congenital malformation that leads to a significantly reduced brain size and is often accompanied by developmental delay.

28 Oct 2025

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

Maternal peanut and peanut butter consumption during pregnancy and breastfeeding shaped DNA methylation patterns in children, particularly in genes regulating neurodevelopment and inflammation. These findings suggest maternal diet can prime offspring epigenetic sensitivity to breastfeeding duration.

27 Oct 2025

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

Study reveals that group B [FeFe]-hydrogenase is the primary enzyme driving fermentative hydrogen production in the healthy human gut, mainly through Bacteroides species. These genes are significantly depleted in Crohn’s disease, indicating a metabolic shift and altered hydrogen cycling dominated by respiratory bacteria

27 Oct 2025

New study reveals how the glucocorticoid receptor forms complex structures inside cells

Drugs to treat inflammatory and autoimmune diseases - such as asthma, psoriasis, rheumatoid arthritis or Chrousos syndrome - act mainly through the glucocorticoid receptor (GR).

27 Oct 2025

TRF1 protein depletion linked to leaner mice and altered metabolism

A new research paper was published in Volume 17, Issue 9 of Aging-US on September 17, 2025, titled "Depletion of the TRF1 telomere-binding protein leads to leaner mice with altered metabolic profiles."

27 Oct 2025

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

New research from the Champalimaud Foundation (CF) reveals how missing just one essential amino acid can change gene expression and the brain's sensory systems, prompting animals to seek out protein-rich yeast and gut bacteria that help them restore nutritional balance and survive in times of need.

27 Oct 2025

Prenatal air pollution exposure tied to higher autism risk in children

A population-based study of over two million births in Ontario found that prenatal exposure to the sulfate and ammonium components of fine particulate matter (PM₂.₅) was associated with a higher risk of autism spectrum disorder. The risk was greatest during mid to late pregnancy and among infants in urban, lower-income neighborhoods.

26 Oct 2025

Metabolism News and Research

Latest Metabolism News and Research

Understanding how biological sex and gender inequities contribute to suboptimal sepsis treatment

Reducing ketone levels and increasing exercise capacity could help manage diabetic ketoacidosis

Two microbial metabolites compete to control the cells' protein building machinery

Does fasting earlier in the day improve metabolism? This study says no

Aligning your body clock may protect your heart and metabolism, says AHA

AI indelibly transforms solid tumor drug development

Experimental compound reduces cell death, inflammation, and organ damage in diabetes

Hydroxytyrosol from olives shows new promise as a brain-protective compound

Circadian rhythm disruptions may increase the risk of cardiovascular disease

Tryptophan deficiency in breast milk may explain health challenges in children born to mothers with HIV

Researchers discover a previously unknown genetic cause for microcephaly

Eating peanuts while pregnant may influence how a child’s genes respond to breastfeeding

Scientists uncover the gut’s hidden hydrogen engine and how it falters in Crohn’s disease

New study reveals how the glucocorticoid receptor forms complex structures inside cells

TRF1 protein depletion linked to leaner mice and altered metabolism

Lack of essential amino acid prompts animals to seek out protein-rich yeast and gut bacteria

Prenatal air pollution exposure tied to higher autism risk in children

Mitochondria and lysosomes work together to control regulatory T cell activation

Study reveals how brain activity, energy use, and blood flow interact during sleep

Dietary fat dictates seasonal eating rhythms, study finds

Advancing brain microphysiological systems (bMPS)

PhD researcher at LifeArc

Unveiling Hidden Potential: Organoids for Disease Modeling in Neuroscience Research