Pharmacology News and Research

Latest Pharmacology News and Research

Long-term use of testosterone therapy in hypogonadal men may reduce risk of death from CV disease

Despite the continued controversy surrounding the use of testosterone in men who have testosterone deficiency (hypogonadism), a new study has found that long-term use of testosterone therapy not only improves vigor and vitality, but may reduce the risk of death due to cardiovascular (CV) disease.

13 Feb 2017

Researchers use liquid biopsies, tiny experimental device to predict cancer spread and hasten diagnosis

A team of investigators from Cedars-Sinai and UCLA is using a new blood-analysis technique and tiny experimental device to help physicians predict which cancers are likely to spread by identifying and characterizing tumor cells circulating through the blood.

13 Feb 2017

Duke Health researchers identify potential new drug target for Huntington's disease

The loss of motor function and mental acuity associated with Huntington's disease might be treatable by restoring a cellular quality control process, which Duke Health researchers have identified as a key factor in the degenerative illness.

13 Feb 2017

Study reveals new role for cancer drug in tumor immunology

A drug first designed to prevent cancer cells from multiplying has a second effect: it switches immune cells that turn down the body's attack on tumors back into the kind that amplify it. This is the finding of a study led by researchers from NYU Langone Medical Center and published recently in Cancer Immunology Research.

13 Feb 2017

Research suggests new type of congenital muscular dystrophy

A newly discovered mutation in the INPP5K gene, which leads to short stature, muscle weakness, intellectual disability, and cataracts, suggests a new type of congenital muscular dystrophy.

10 Feb 2017

VA scientists reveal new theory on how aspirin may ward off cancer

Studies abound that point to a role for plain old aspirin in keeping deadly cancers at bay. While aspirin is not yet part of mainstream treatment for any cancer, it is recommended by the U.S. Preventive Services Task Force for certain adults to help prevent colorectal cancer.

8 Feb 2017

Study sheds light on role of brain region in social behavior and pathology in autism

Researchers at Rosalind Franklin University of Medicine and Science have induced empathy-like behavior by identifying then manipulating a brain circuit in an experimental model, an indication that new strategies may help people with autism spectrum disorder gain social abilities.

8 Feb 2017

Researchers find drugs that could replicate effects of gastric bypass surgery

Gastric bypass surgery is one of the most successful treatments for obesity and related disorders; however, some patients may not want to undergo surgery.

8 Feb 2017

Smokers more likely to die from colon cancer than non-smokers, study shows

In an analysis of more than 18,000 patients treated for colon cancer, current smokers were 14 percent more likely to die from their colon cancer within five years than patients who had never smoked.

8 Feb 2017

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

For many newborn babies, an enzyme that breaks down the molecule bilirubin doesn't activate right away. The resulting bilirubin buildup can lead to jaundice, a typically harmless condition that causes a baby's skin to temporarily appear yellow.

6 Feb 2017

Study provides insights into functions of astrocytes following brain injury or disease

Astrocytes have long been implicated in the pathology of a range of human neurodegenerative diseases or injuries including Alzheimer's, Huntington's Parkinson's disease, brain trauma and spinal cord injury.

3 Feb 2017

‘Love hormone’ from insects could be used as drug lead to prevent uterine contractility in preterm labour

In a recent study published in "Scientific Reports", an international team of researchers led by MedUni Vienna report that an oxytocin-like neuropeptide ("inotocin") exhibited a specific pharmacological profile for the human receptors of oxytocin (known as the "love hormone") and vasopressin.

1 Feb 2017

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Although one of the most serious complications of cirrhosis is liver cancer, or hepatocellular carcinoma (HCC), an analysis of health records revealed that the 10-year incidence of HCC in UK patients with cirrhosis is four percent or lower.

1 Feb 2017

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

One of the earliest signs of Alzheimer's disease is a decline in glucose levels in the brain. It appears in the early stages of mild cognitive impairment -- before symptoms of memory problems begin to surface.

31 Jan 2017

Delays in availability of new treatments and incomprehensible price rises disadvantage cancer patients

Cancer patients are living longer and in many cases the disease is becoming chronic rather than acute. Access to drugs that help extend life and improve quality of life, and fair prices for those drugs are therefore essential for more and more people.

28 Jan 2017

LSD influences perception by stimulating serotonin receptors in the brain

Researchers from UZH have discovered how the perception of meaning changes in the brain under the influence of LSD. The serotonin 2A receptors are responsible for altered perception.

27 Jan 2017

Scientists discover new way to inhibit growth of glioblastoma

Scientists have found a way to inhibit the growth of glioblastoma, a type of brain cancer with low survival rates, by targeting a protein that drives growth of brain tumors, according to research from the Peter O'Donnell Jr. Brain Institute and Harold C. Simmons Comprehensive Cancer Center.

25 Jan 2017

Cervicovaginal microbial communities in pregnant woman may be key to preventing preterm birth

A team of researchers that has confirmed the presence of bacteria in a woman's vagina and cervix may either increase the risk of premature birth or have a protective effect against it, has won the March of Dimes Award for Best Abstract on Prematurity at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting. The findings will be presented Thursday, January 26, at 1:15 p.m. PST at Caesars Palace Augustus Ballroom in Las Vegas.

24 Jan 2017

Researchers uncover mechanism of resistance used by triple negative breast cancer

Breast cancer cells are evasive, finding ways to bypass drugs designed to stop their unchecked growth.

20 Jan 2017

Pre-operative enteral nutrition linked to reduced rates of complications after Crohn's disease surgery

Despite improvements in medical care, about two-thirds of patients with Crohn's disease develop complications requiring intestinal surgery at some time, and post-operative healing can be complicated.

20 Jan 2017

Pharmacology News and Research

Latest Pharmacology News and Research

Long-term use of testosterone therapy in hypogonadal men may reduce risk of death from CV disease

Researchers use liquid biopsies, tiny experimental device to predict cancer spread and hasten diagnosis

Duke Health researchers identify potential new drug target for Huntington's disease

Study reveals new role for cancer drug in tumor immunology

Research suggests new type of congenital muscular dystrophy

VA scientists reveal new theory on how aspirin may ward off cancer

Study sheds light on role of brain region in social behavior and pathology in autism

Researchers find drugs that could replicate effects of gastric bypass surgery

Smokers more likely to die from colon cancer than non-smokers, study shows

Study could provide novel therapeutic approach for preventing severe jaundice in newborn babies

Study provides insights into functions of astrocytes following brain injury or disease

‘Love hormone’ from insects could be used as drug lead to prevent uterine contractility in preterm labour

New analysis reveals low incidence of liver cancer in patients with cirrhosis

Glucose deprivation in the brain triggers onset of cognitive decline, research shows

Delays in availability of new treatments and incomprehensible price rises disadvantage cancer patients

LSD influences perception by stimulating serotonin receptors in the brain

Scientists discover new way to inhibit growth of glioblastoma

Cervicovaginal microbial communities in pregnant woman may be key to preventing preterm birth

Researchers uncover mechanism of resistance used by triple negative breast cancer

Pre-operative enteral nutrition linked to reduced rates of complications after Crohn's disease surgery

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Pharmacology News and Research

Latest Pharmacology News and Research

Pittcon Highlights: Pharmaceutical & Biologic eBook

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Automating research - solutions and best practices

How can microdialysis benefit drug development

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