Pharmacology News and Research

Latest Pharmacology News and Research

Taking antidepressants with painkillers dangerous

Taking antidepressants together with painkillers can substantially increase the risk of bleeding from the stomach, according to new research by the University of East Anglia.

9 Oct 2007

SSRIs may double risk of gastrointestinal bleeding

New research shows that selective serotonin reuptake inhibitors (SSRIs), a group of drugs commonly used to treat depression, may double the risk of gastrointestinal bleeding, according to researchers from Wake Forest University School of Medicine and colleagues.

9 Oct 2007

Researchers create modular, multi-functional drug delivery system

There are two aspects to creating an effective drug: finding a chemical compound that has the desired biological effect and minimal side-effects and then delivering it to the right place in the body for it to do its job.

8 Oct 2007

Individually tailored herbal concoctions possibly harmful

Scientists in Britain are warning that there is no evidence to suggest herbal medicines "tailored" to the individual do actually work; they also say such concoctions may even be harmful.

4 Oct 2007

More research needed on sex differences in lung cancer

The Society for Women's Health Research gathered three lung cancer experts on Capitol Hill on September 17, 2007 to inform Congress on the need for increased funding to research lung cancer and its impact on women.

1 Oct 2007

Stealth learning fosters science education

Rochelle Schwartz-Bloom, a Duke University pharmacology professor who left the lab bench to focus on science education, has developed a tactic for keeping students hands in the air at the end of class.

27 Sep 2007

New molecular target in blood clot formation

Researchers at the University of Illinois at Chicago College of Medicine have identified a new molecular target in blood clot formation, which seems to reduce clotting without excessive bleeding, the common side-effect of anti-clotting agents.

27 Sep 2007

Enzyme's second messenger contributes to cell overgrowth

Scientists at the University of California, San Diego (UCSD) School of Medicine have uncovered a novel pathway by which hormones elevated in inflammation, cancer and cell injury act on cells to stimulate their growth.

27 Sep 2007

New nanoprobe imaging station helps study the distribution of elements in cells

Scientists suspect that iron accumulation plays a role in neurodegenerative processes such as Parkinson's disease, but its distribution in neurons has never been observed because of the lack of techniques to do so. Until today.

26 Sep 2007

Use of energy drinks in conjunction with alcohol popular among Italian university students

Energy drinks - known for their stimulant effects on the central nervous system - have become more and more popular among young people in recent years.

25 Sep 2007

Study reveals the regulatory mechanism of protein kinase A

Research conducted at the University of California, San Diego (UCSD) School of Medicine has shed new light on the structure and function of one of the key proteins in all mammalian cells, protein kinase A (PKA), an enzyme which plays an essential role in memory formation, communication between nerve cells, and cardiac function.

21 Sep 2007

Circulating fats kill transplanted pancreas cells

New findings by UT Southwestern Medical Center researchers show that a byproduct of cholesterol metabolism interferes with the beneficial effects estrogen has on the cardiovascular system, providing a better understanding of the interplay between cholesterol and estrogen in heart disease.

18 Sep 2007

Byproduct of cholesterol metabolism blocks heart health benefits of estrogen

17 Sep 2007

World's longest-running study of the health effects of low levels of mercury exposure

The presence of mercury in dental amalgams, or fillings, is relatively common knowledge; however, whether its presence affects the neurological system is a debate that has been ongoing for 150 years.

13 Sep 2007

Analysis of aspartame

A report published in the September issue of Critical Reviews in Toxicology (Volume 37, Issue 8, pp. 629-727) systematically evaluates virtually all available scientific information about aspartame and concludes that the low calorie sweetener is safe.

12 Sep 2007

Scientists speed healing of bone damage

Blocking a naturally occurring inhibitor of bone formation accelerates healing of skull defects in mice, say researchers at the Stanford University School of Medicine and Lucile Packard Children's Hospital. The finding advances the understanding of how the skeleton develops and opens new therapeutic avenues for many of the disorders that are expected to afflict aging baby boomers.

5 Sep 2007

Radiation and drug combo helps boost efficacy of lung-cancer treatment

Combining radiation therapy with a drug that helps destroy blood vessels nourishing malignant tumors has been shown in mice to be significantly more effective in treating lung cancer than either approach alone, researchers at UT Southwestern Medical Center have found.

5 Sep 2007

Improved dosing formula for warfarin (Coumadin)

Doctors prescribing blood thinners have had to go through a lengthy trial-and-error process to arrive at the optimal dose for their patients.

5 Sep 2007

Red wine for prostate cancer

Researchers at the University of Alabama at Birmingham (UAB) have found that nutrients in red wine may help reduce the risk of developing prostate cancer. The study involved male mice that were fed a plant compound found in red wine called resveratrol, which has shown anti-oxidant and anti-cancer properties.

3 Sep 2007